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CENPO
Description
centromere protein O
Image
GO Annotations
Cellular Component
Chromosome, Centromeric Region
Kinetochore
Inner Kinetochore
Nucleus
Nucleoplasm
Chromosome
Cytosol
Nuclear Body
Mis6-Sim4 Complex
Molecular Function
Protein Binding
Biological Process
Chromosome Segregation
Centromere Complex Assembly
Pathways
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
RHO GTPases Activate Formins
Deposition of new CENPA-containing nucleosomes at the centromere
Mitotic Prometaphase
EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS
Body fat distribution (arm fat ratio) (
30664634
)
Body fat distribution (trunk fat ratio) (
30664634
)
Body fat mass (
28552196
)
Body mass index (
29273807
26426971
)
Body mass index (age <50) (
26426971
)
Body mass index (age>50) (
26426971
)
Body mass index x sex x age interaction (4df test) (
26426971
)
Cognitive function (
28093568
)
Coronary artery disease (
29212778
)
Height (
23563607
28552196
25282103
)
Multiple sclerosis (
24076602
)
Peginterferon alfa-2a treatment response in chronic hepatitis B infection (
30972912
)
Trunk fat mass (
28552196
)
Type 1 diabetes (
21980299
)
Waist circumference adjusted for body mass index (
34021172
)
Novel Interacting Genes
1 novel interacting genes:
DRC1
Interacting Genes
6 interacting genes:
CEP170P1
DCDC2
ERI3
FOS
FOSB
NECAB2
Entrez ID
79172
HPRD ID
14414
Ensembl ID
ENSG00000138092
Uniprot IDs
Q9BU64
PDB IDs
7PB8
7PKN
7QOO
7R5S
7R5V
7XHN
7XHO
7YWX
7YYH
Enriched GO Terms of Interacting Partners
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Response To Corticosterone
Response To Progesterone
Response To Mineralocorticoid
Response To Prolactin
Response To Ethanol
Double-stranded DNA Binding
Conditioned Taste Aversion
Female Pregnancy
Response To Calcium Ion
Response To CAMP
Medium-term Memory
Response To Glucocorticoid
Cellular Response To Prolactin
Cellular Response To Calcium Ion
Axoneme
Negative Regulation Of G Protein-coupled Receptor Internalization
Positive Regulation Of Adenosine Receptor Signaling Pathway
A2A Adenosine Receptor Binding
Response To Purine-containing Compound
Response To Corticosteroid
Type 5 Metabotropic Glutamate Receptor Binding
Cellular Response To Metal Ion
Transcription Factor AP-1 Complex
Cellular Response To Zinc Ion Starvation
Response To Mechanical Stimulus
Response To Gravity
Response To Ketone
Response To Steroid Hormone
Kinocilium
Skeletal Muscle Cell Proliferation
Cellular Response To Phorbol 13-acetate 12-myristate
Positive Regulation Of Glutamate Receptor Signaling Pathway
Mucociliary Clearance
Myoblast Proliferation
Cellular Response To Parathyroid Hormone Stimulus
Response To Phorbol 13-acetate 12-myristate
Response To Alcohol
Cilium Assembly
Regulation Of Glutamate Receptor Signaling Pathway
Axonemal Dynein Complex
Response To Xenobiotic Stimulus
Transcription By RNA Polymerase II
Cilium Organization
Response To Parathyroid Hormone
Response To Forskolin
Neural Retina Development
Response To Metal Ion
Behavioral Response To Cocaine
Response To Morphine
Negative Regulation Of Receptor Internalization
Tagcloud
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