POR and FANCC

Number of citations of the paper that reports this interaction (PMID 9787138)
23

Data Source:
BioGRID (affinity chromatography technology, biochemical, two hybrid)

		POR	FANCC
Gene Name		P450 (cytochrome) oxidoreductase	Fanconi anemia, complementation group C
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Mitochondrion Endoplasmic Reticulum Membrane Membrane Intracellular Membrane-bounded Organelle	Nucleus Nucleoplasm Cytoplasm Cytosol Fanconi Anaemia Nuclear Complex
	Molecular Function	NADPH-hemoprotein Reductase Activity Cytochrome-b5 Reductase Activity, Acting On NAD(P)H Iron Ion Binding Protein Binding Nitric Oxide Dioxygenase Activity Electron Carrier Activity FMN Binding Hydrolase Activity Enzyme Binding Iron-cytochrome-c Reductase Activity Flavin Adenine Dinucleotide Binding NADP Binding	Protein Binding
	Biological Process	Regulation Of Growth Plate Cartilage Chondrocyte Proliferation Response To Nutrient Carnitine Metabolic Process Flavonoid Metabolic Process Internal Peptidyl-lysine Acetylation Fatty Acid Oxidation Positive Regulation Of Chondrocyte Differentiation Positive Regulation Of Monooxygenase Activity Response To Drug Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Nitrate Catabolic Process Positive Regulation Of Cholesterol Biosynthetic Process Positive Regulation Of Smoothened Signaling Pathway Nitric Oxide Catabolic Process Oxidation-reduction Process Negative Regulation Of Lipase Activity Demethylation Cellular Response To Follicle-stimulating Hormone Stimulus Cellular Response To Peptide Hormone Stimulus Positive Regulation Of Steroid Hormone Biosynthetic Process Cellular Organofluorine Metabolic Process	Myeloid Cell Homeostasis DNA Repair Nucleotide-excision Repair Protein Complex Assembly Germ Cell Development Removal Of Superoxide Radicals
Pathways			Fanconi Anemia pathway
Drugs		Flavin-Adenine Dinucleotide Riboflavin Monophosphate 2\'-Monophosphoadenosine 5\'-Diphosphoribose
Diseases
GWAS
Protein-Protein Interactions		14 interactors: CYB5A CYP17A1 CYP1A2 CYP2A6 CYP2C19 CYP2C9 CYP2D6 CYP2E1 CYP3A4 FANCC HMOX1 RABEPK STAT1 XRCC6	27 interactors: ATP6 AZIN1 CAPN10 CDK1 DNAJB1 FANCA FANCD2 FANCE FANCF FANCG GSTP1 HSP90AA1 HSP90B1 HSPA1A HSPA4 HSPA8 IK KRT1 POR RPL18 RPS3A SPTA1 SPTAN1 STAT1 TCERG1 USP14 ZBTB32
Entrez ID		5447	2176
HPRD ID		00485	01967
Ensembl ID		ENSG00000127948	ENSG00000158169
Uniprot IDs		E7EVY7 F5H468 P16435	B4E3W2 Q00597
PDB IDs		1B1C 3FJO 3QE2 3QFC 3QFR 3QFS 3QFT
Enriched GO Terms of Interacting Partners?		Monoterpenoid Metabolic Process Exogenous Drug Catabolic Process Drug Catabolic Process Drug Metabolic Process Xenobiotic Metabolic Process Cellular Response To Xenobiotic Stimulus Response To Xenobiotic Stimulus Epoxygenase P450 Pathway Steroid Metabolic Process Arachidonic Acid Metabolic Process Response To Drug Icosanoid Metabolic Process Unsaturated Fatty Acid Metabolic Process Long-chain Fatty Acid Metabolic Process Isoprenoid Metabolic Process Oxidative Demethylation Oxidation-reduction Process Omega-hydroxylase P450 Pathway Fatty Acid Metabolic Process Alkaloid Metabolic Process Carboxylic Acid Metabolic Process Demethylation Small Molecule Metabolic Process Organic Acid Metabolic Process Response To Inorganic Substance Lipid Metabolic Process Monocarboxylic Acid Metabolic Process Cellular Lipid Metabolic Process Alkaloid Catabolic Process Catabolic Process Response To Reactive Oxygen Species Heterocycle Metabolic Process Response To Cadmium Ion Response To Stimulus Coumarin Metabolic Process Cellular Response To Stimulus Dibenzo-p-dioxin Metabolic Process Cellular Response To Cadmium Ion Response To Oxidative Stress Steroid Catabolic Process Cellular Metabolic Process Androgen Metabolic Process Porphyrin-containing Compound Metabolic Process Positive Regulation Of Smooth Muscle Cell Proliferation Negative Regulation Of Cellular Organofluorine Metabolic Process Negative Regulation Of Macrophage Fusion Oxidative Deethylation Response To Acetate Toxin Biosynthetic Process Response To Lipopolysaccharide	Protein Refolding Response To Unfolded Protein Cellular Response To Stress Regulation Of Cellular Response To Heat Response To Stress Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Cellular Response To Heat DNA Repair Response To Stimulus Protein Import Into Mitochondrial Outer Membrane Response To Heat Protein Folding Response To Abiotic Stimulus Cellular Response To DNA Damage Stimulus Membrane Organization Cellular Metabolic Process Response To Organic Substance Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Negative Regulation Of Inclusion Body Assembly Response To Temperature Stimulus Axon Guidance Response To Oxidative Stress Response To External Stimulus Chaperone-mediated Protein Complex Assembly DNA Metabolic Process Establishment Of Protein Localization To Membrane Nucleobase-containing Compound Metabolic Process Chaperone Mediated Protein Folding Requiring Cofactor Regulation Of Apoptotic Process Cellular Response To Organonitrogen Compound Regulation Of Inclusion Body Assembly Regulation Of Cell Death Protein Localization To Organelle Female Gonad Development Axonogenesis Development Of Primary Female Sexual Characteristics Cellular Macromolecule Catabolic Process Viral Process Cellular Response To Peptide Hormone Stimulus Axon Development Positive Regulation Of Immune System Process Negative Regulation Of Apoptotic Process Cellular Response To Peptide Nitric Oxide Metabolic Process Cell Morphogenesis Involved In Neuron Differentiation Regulation Of Immune System Process Negative Regulation Of Programmed Cell Death Metabolic Process
Tagcloud ?		5c 7h adjuvant aluminiumphosphate bactericidal class deoxycholate donors engineered extraction final formulated genetically meningococcal mixed omps omv outer p1 pora prepared represent safe serogroup served strains vaccine vaccines vesicles	1beta autoinhibitory bm characterizes creating cytokines fanca fanconi hypersensitive inactivated leukemic loop mapkapk mononuclear multipotent overproduced overproduction p38 phagocytes posttranscriptionally potently progenitor progenitors progressive reasoning tlr toll transcriptionally
Tagcloud (Difference) ?		5c 7h adjuvant aluminiumphosphate bactericidal class deoxycholate donors engineered extraction final formulated genetically meningococcal mixed omps omv outer p1 pora prepared represent safe serogroup served strains vaccine vaccines vesicles	1beta autoinhibitory bm characterizes creating cytokines fanca fanconi hypersensitive inactivated leukemic loop mapkapk mononuclear multipotent overproduced overproduction p38 phagocytes posttranscriptionally potently progenitor progenitors progressive reasoning tlr toll transcriptionally
Tagcloud (Intersection) ?