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POLR2D and POLR2G
Number of citations of the paper that reports this interaction (PubMedID
35271311
)
106
Data Source:
BioGRID
(affinity chromatography technology, biochemical, cross-linking study)
HPRD
(in vivo, two hybrid, in vitro)
POLR2D
POLR2G
Description
RNA polymerase II subunit D
RNA polymerase II subunit G
Image
GO Annotations
Cellular Component
DNA-directed RNA Polymerase Complex
Nucleus
Nucleoplasm
RNA Polymerase II, Core Complex
Cytosol
Nuclear Speck
RNA Polymerase Complex
DNA-directed RNA Polymerase Complex
P-body
Nucleus
Nucleoplasm
RNA Polymerase II, Core Complex
Molecular Function
Nucleotide Binding
Protein Binding
Translation Initiation Factor Binding
Nucleic Acid Binding
Single-stranded DNA Binding
RNA Binding
Single-stranded RNA Binding
Protein Binding
Translation Initiation Factor Binding
Biological Process
DNA-templated Transcription Initiation
Transcription By RNA Polymerase II
Transcription Initiation At RNA Polymerase II Promoter
Nuclear-transcribed MRNA Catabolic Process
DNA-templated Transcription
DNA-templated Transcription Initiation
Transcription By RNA Polymerase II
Transcription Initiation At RNA Polymerase II Promoter
Positive Regulation Of Translational Initiation
Positive Regulation Of Nuclear-transcribed MRNA Poly(A) Tail Shortening
Pathways
Formation of RNA Pol II elongation complex
Formation of the Early Elongation Complex
Formation of HIV elongation complex in the absence of HIV Tat
Formation of the HIV-1 Early Elongation Complex
RNA Pol II CTD phosphorylation and interaction with CE during HIV infection
HIV Transcription Initiation
RNA Polymerase II HIV Promoter Escape
Transcription of the HIV genome
Formation of HIV-1 elongation complex containing HIV-1 Tat
Formation of HIV-1 elongation complex containing HIV-1 Tat
Pausing and recovery of Tat-mediated HIV elongation
Abortive elongation of HIV-1 transcript in the absence of Tat
Tat-mediated HIV elongation arrest and recovery
Tat-mediated elongation of the HIV-1 transcript
HIV elongation arrest and recovery
Pausing and recovery of HIV elongation
Viral Messenger RNA Synthesis
MicroRNA (miRNA) biogenesis
Transcriptional regulation by small RNAs
PIWI-interacting RNA (piRNA) biogenesis
Activation of anterior HOX genes in hindbrain development during early embryogenesis
RNA Polymerase II Pre-transcription Events
Formation of TC-NER Pre-Incision Complex
Transcription-Coupled Nucleotide Excision Repair (TC-NER)
Dual incision in TC-NER
Gap-filling DNA repair synthesis and ligation in TC-NER
TP53 Regulates Transcription of DNA Repair Genes
FGFR2 alternative splicing
RNA polymerase II transcribes snRNA genes
RNA polymerase II transcribes snRNA genes
mRNA Capping
mRNA Splicing - Major Pathway
mRNA Splicing - Minor Pathway
Processing of Capped Intron-Containing Pre-mRNA
RNA Polymerase II Promoter Escape
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
RNA Polymerase II Transcription Initiation
RNA Polymerase II Transcription Elongation
RNA Polymerase II Transcription Initiation And Promoter Clearance
RNA Pol II CTD phosphorylation and interaction with CE
Signaling by FGFR2 IIIa TM
Estrogen-dependent gene expression
Inhibition of DNA recombination at telomere
Formation of RNA Pol II elongation complex
Formation of the Early Elongation Complex
Formation of HIV elongation complex in the absence of HIV Tat
Formation of the HIV-1 Early Elongation Complex
RNA Pol II CTD phosphorylation and interaction with CE during HIV infection
HIV Transcription Initiation
RNA Polymerase II HIV Promoter Escape
Transcription of the HIV genome
Formation of HIV-1 elongation complex containing HIV-1 Tat
Formation of HIV-1 elongation complex containing HIV-1 Tat
Pausing and recovery of Tat-mediated HIV elongation
Abortive elongation of HIV-1 transcript in the absence of Tat
Tat-mediated HIV elongation arrest and recovery
Tat-mediated elongation of the HIV-1 transcript
HIV elongation arrest and recovery
Pausing and recovery of HIV elongation
Viral Messenger RNA Synthesis
MicroRNA (miRNA) biogenesis
Transcriptional regulation by small RNAs
PIWI-interacting RNA (piRNA) biogenesis
Activation of anterior HOX genes in hindbrain development during early embryogenesis
RNA Polymerase II Pre-transcription Events
Formation of TC-NER Pre-Incision Complex
Transcription-Coupled Nucleotide Excision Repair (TC-NER)
Dual incision in TC-NER
Gap-filling DNA repair synthesis and ligation in TC-NER
TP53 Regulates Transcription of DNA Repair Genes
FGFR2 alternative splicing
RNA polymerase II transcribes snRNA genes
RNA polymerase II transcribes snRNA genes
mRNA Capping
mRNA Splicing - Major Pathway
mRNA Splicing - Minor Pathway
Processing of Capped Intron-Containing Pre-mRNA
RNA Polymerase II Promoter Escape
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
RNA Polymerase II Transcription Initiation
RNA Polymerase II Transcription Elongation
RNA Polymerase II Transcription Initiation And Promoter Clearance
RNA Pol II CTD phosphorylation and interaction with CE
Signaling by FGFR2 IIIa TM
Estrogen-dependent gene expression
Inhibition of DNA recombination at telomere
Drugs
Diseases
GWAS
Apolipoprotein A1 levels (
32203549
)
HDL cholesterol levels (
32203549
)
Waist-to-hip ratio adjusted for BMI (
26426971
)
Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) (
26426971
)
Interacting Genes
16 interacting genes:
ATF7IP
EMX1
ESR1
HOXC9
IKBKG
NR5A2
POLR2A
POLR2B
POLR2C
POLR2E
POLR2G
POLR2H
POLR2K
POLR2L
TRIM29
ZSCAN1
45 interacting genes:
ATF7IP
BCL2L15
C22orf15
CIB3
CNTNAP2
DDX54
DES
DUSP29
EIF3D
EIF4A3
EWSR1
FNDC4
FOSL2
GPKOW
HOXC5
KIF5B
LMO2
MAPK1
MCM3AP
MCPH1
MYOD1
NOTCH2NLA
NTRK2
OSGIN1
PARVG
POLR1C
POLR2A
POLR2C
POLR2D
POLR2E
POLR2F
POLR2H
PRKRA
PSMB8
RPAP1
TAF15
TNNC1
TRAPPC2L
TRIM14
TRIM68
TSEN15
UPRT
VHL
WHR1
ZNF410
Entrez ID
5433
5436
HPRD ID
16191
15995
Ensembl ID
ENSG00000144231
ENSG00000168002
Uniprot IDs
O15514
P62487
PDB IDs
2C35
5IY6
5IY7
5IY8
5IY9
5IYA
5IYB
5IYC
5IYD
6DRD
6O9L
6XRE
7LBM
9EHZ
9EI1
9EI3
9EI4
2C35
5IY6
5IY7
5IY8
5IY9
5IYA
5IYB
5IYC
5IYD
6DRD
6O9L
6XRE
7LBM
9EHZ
9EI1
9EI3
9EI4
Enriched GO Terms of Interacting Partners
?
RNA Polymerase II, Core Complex
DNA-directed RNA Polymerase Complex
DNA-directed RNA Polymerase Activity
DNA-templated Transcription
Transcription By RNA Polymerase II
RNA Polymerase I Complex
Nucleobase-containing Compound Biosynthetic Process
RNA Polymerase III Complex
DNA Binding
RNA Metabolic Process
Macromolecule Biosynthetic Process
Nucleoplasm
Nucleic Acid Metabolic Process
RNA-directed RNA Polymerase Activity
RNA-templated Transcription
Regulation Of RNA Metabolic Process
Nucleus
Transcription By RNA Polymerase III
Regulation Of Nucleobase-containing Compound Metabolic Process
Regulation Of DNA-templated Transcription
Regulation Of RNA Biosynthetic Process
Zinc Ion Binding
Nucleobase-containing Compound Metabolic Process
5'-3' RNA Polymerase Activity
TRNA Transcription By RNA Polymerase III
TRNA Transcription
Regulation Of Gene Expression
Regulation Of Macromolecule Biosynthetic Process
Nucleolus
Sequence-specific Double-stranded DNA Binding
Regulation Of Primary Metabolic Process
Regulation Of Macromolecule Metabolic Process
Ovulation Cycle Process
Transcription Coregulator Binding
Regulation Of Transcription By RNA Polymerase I
Regulation Of Transcription By RNA Polymerase II
Zygotic Genome Activation
Nuclear Receptor Activity
DNA-templated Transcription Elongation
Regulation Of Metabolic Process
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
Positive Regulation Of Glucocorticoid Biosynthetic Process
Positive Regulation Of Tendon Cell Differentiation
Primary Ovarian Follicle Growth
Metal Ion Binding
Chromatin
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
Prostate Epithelial Cord Elongation
Positive Regulation Of Nitric-oxide Synthase Activity
Morula Formation
DNA-directed RNA Polymerase Complex
RNA Polymerase II, Core Complex
DNA-directed RNA Polymerase Activity
RNA Polymerase I Complex
RNA Polymerase III Complex
Nucleoplasm
Transcription By RNA Polymerase II
DNA-templated Transcription
Nucleus
Cerebral Cortex Development
Nucleolus
RNA Metabolic Process
Nucleobase-containing Compound Biosynthetic Process
Nucleic Acid Binding
Cellular Response To Brain-derived Neurotrophic Factor Stimulus
Outer Ear Morphogenesis
Macromolecule Biosynthetic Process
Transcription Coregulator Activity
TRNA Transcription By RNA Polymerase III
TRNA Transcription
Contractile Muscle Fiber
Macromolecule Metabolic Process
Nucleic Acid Metabolic Process
Nucleobase-containing Compound Metabolic Process
Striatum Development
Transcription By RNA Polymerase I
DNA Binding
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Tagcloud (Difference)
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Tagcloud (Intersection)
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