POLR2D and HOXC9

Number of citations of the paper that reports this interaction (PMID 20211142)
148

Data Source:
BioGRID (two hybrid)

		POLR2D	HOXC9
Gene Name		polymerase (RNA) II (DNA directed) polypeptide D	homeobox C9
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Gene Ontology Annotations	Cellular Component	Cytoplasmic MRNA Processing Body Nucleus Nucleoplasm DNA-directed RNA Polymerase II, Core Complex	Nucleus
	Molecular Function	Nucleotide Binding Single-stranded DNA Binding Single-stranded RNA Binding DNA-directed RNA Polymerase Activity Translation Initiation Factor Binding	Sequence-specific DNA Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay MRNA Splicing, Via Spliceosome DNA Repair Transcription-coupled Nucleotide-excision Repair Nucleotide-excision Repair Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Transcription Elongation From RNA Polymerase II Promoter 7-methylguanosine MRNA Capping RNA Splicing Gene Expression Viral Process MRNA Export From Nucleus In Response To Heat Stress Recruitment Of 3'-end Processing Factors To RNA Polymerase II Holoenzyme Complex PiRNA Metabolic Process Somatic Stem Cell Maintenance Positive Regulation Of Translational Initiation Positive Regulation Of Viral Transcription	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Anterior/posterior Pattern Specification Embryonic Skeletal System Morphogenesis
Pathways		RNA Polymerase II Promoter Escape mRNA Splicing Formation of HIV-1 elongation complex containing HIV-1 Tat PIWI-interacting RNA (piRNA) biogenesis Nucleotide Excision Repair RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription Abortive elongation of HIV-1 transcript in the absence of Tat HIV Infection Regulatory RNA pathways Formation of the Early Elongation Complex Tat-mediated elongation of the HIV-1 transcript Tat-mediated HIV elongation arrest and recovery Formation of transcription-coupled NER (TC-NER) repair complex RNA Pol II CTD phosphorylation and interaction with CE RNA Polymerase II Pre-transcription Events Dual incision reaction in TC-NER Influenza Life Cycle HIV elongation arrest and recovery HIV Life Cycle HIV Transcription Initiation Influenza Viral RNA Transcription and Replication RNA Pol II CTD phosphorylation and interaction with CE Transcriptional regulation of pluripotent stem cells RNA Polymerase II HIV Promoter Escape HIV Transcription Elongation POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation Transcriptional regulation by small RNAs Processing of Capped Intron-Containing Pre-mRNA mRNA Capping mRNA Splicing - Minor Pathway mRNA Splicing - Major Pathway MicroRNA (miRNA) biogenesis Influenza Infection Pausing and recovery of Tat-mediated HIV elongation Late Phase of HIV Life Cycle Formation of RNA Pol II elongation complex RNA Polymerase II Transcription Initiation And Promoter Clearance Pausing and recovery of HIV elongation Formation of HIV elongation complex in the absence of HIV Tat Transcription-coupled NER (TC-NER) Viral Messenger RNA Synthesis Formation of the HIV-1 Early Elongation Complex RNA Polymerase II Transcription Initiation Transcription of the HIV genome RNA Polymerase II Transcription Elongation
Drugs
Diseases
GWAS
Protein-Protein Interactions		16 interactors: ATF7IP EMX1 ESR1 HOXC9 IKBKG NR5A2 POLR2A POLR2B POLR2C POLR2E POLR2G POLR2H POLR2K POLR2L TRIM29 ZSCAN1	16 interactors: CBX6 ELAVL2 GMNN GTF2A1L HOXC13 HOXD1 HOXD9 IRF9 LPXN NMI PCGF2 POLR2D POLR3D POU2F1 ZFP36 ZNF384
Entrez ID		5433	3225
HPRD ID		16191	00857
Ensembl ID		ENSG00000144231	ENSG00000180806
Uniprot IDs		E9PB93 E9PHV4 O15514	P31274 Q8N561
PDB IDs		2C35	2LP0
Enriched GO Terms of Interacting Partners?		7-methylguanosine MRNA Capping PiRNA Metabolic Process 7-methylguanosine RNA Capping Positive Regulation Of Viral Process Transcription-coupled Nucleotide-excision Repair Positive Regulation Of Viral Transcription Transcription Initiation From RNA Polymerase II Promoter Transcription Elongation From RNA Polymerase II Promoter DNA-templated Transcription, Initiation Somatic Stem Cell Maintenance Regulation Of Viral Transcription Regulation Of Viral Process DNA-templated Transcription, Elongation Nucleotide-excision Repair Transcription From RNA Polymerase II Promoter Transcription, DNA-templated RNA Biosynthetic Process Stem Cell Maintenance Viral Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Metabolic Process Stem Cell Development Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Gene Expression Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Cellular Macromolecule Biosynthetic Process Stem Cell Differentiation Macromolecule Biosynthetic Process Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process RNA Splicing MRNA Processing Termination Of RNA Polymerase III Transcription Transcription Elongation From RNA Polymerase III Promoter Nucleobase-containing Compound Metabolic Process NcRNA Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process MRNA Metabolic Process Cellular Response To DNA Damage Stimulus Cellular Nitrogen Compound Metabolic Process RNA Processing Positive Regulation Of Type I Interferon Production DNA Repair Termination Of RNA Polymerase I Transcription	Transcription, DNA-templated RNA Biosynthetic Process RNA Metabolic Process Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Nucleic Acid-templated Transcription Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Regulation Of Gene Expression Cellular Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Transcription From RNA Polymerase II Promoter Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Embryonic Skeletal System Development Regulation Of Cellular Process Cellular Metabolic Process Positive Regulation Of Gene Expression Organ Morphogenesis Transcription From RNA Polymerase III Promoter Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Anterior/posterior Pattern Specification Recruitment Of 3'-end Processing Factors To RNA Polymerase II Holoenzyme Complex MRNA 3'-end Processing MRNA Export From Nucleus In Response To Heat Stress Negative Regulation Of Transcription From RNA Polymerase II Promoter DNA-templated Transcription, Elongation Negative Regulation Of Cellular Metabolic Process RNA 3'-end Processing Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Embryonic Skeletal System Morphogenesis Pattern Specification Process Negative Regulation Of B Cell Receptor Signaling Pathway Olfactory Placode Formation Positive Regulation Of Transcription From RNA Polymerase II Promoter Nuclear-transcribed MRNA Catabolic Process Positive Regulation Of Cellular Metabolic Process
Tagcloud ?			acquisition addressed attenuation chip coordinated coordinates differentiation diverse downregulation e2f6 exit global interacted mapping microarray neuroblastoma neuronal profiling promoters question recruited remarkably repressing repressor seq sets specialized upregulation wide
Tagcloud (Difference) ?			acquisition addressed attenuation chip coordinated coordinates differentiation diverse downregulation e2f6 exit global interacted mapping microarray neuroblastoma neuronal profiling promoters question recruited remarkably repressing repressor seq sets specialized upregulation wide
Tagcloud (Intersection) ?