POLR2G and MYOD1

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		POLR2G	MYOD1
Gene Name		polymerase (RNA) II (DNA directed) polypeptide G	myogenic differentiation 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasmic MRNA Processing Body Nucleus Nucleoplasm DNA-directed RNA Polymerase II, Core Complex Nucleolus	Nuclear Chromatin Nucleus Nucleoplasm Transcription Factor Complex Cytoplasm Myofibril
	Molecular Function	Single-stranded DNA Binding Single-stranded RNA Binding DNA-directed RNA Polymerase Activity Translation Initiation Factor Binding	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Core Promoter Binding RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Transcription Factor Activity Transcription Coactivator Activity Protein Binding Transcription Factor Binding Chromatin DNA Binding Ubiquitin Protein Ligase Binding Nuclear Hormone Receptor Binding Protein Heterodimerization Activity E-box Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic MRNA Splicing, Via Spliceosome DNA Repair Transcription-coupled Nucleotide-excision Repair Nucleotide-excision Repair Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Transcription Elongation From RNA Polymerase II Promoter 7-methylguanosine MRNA Capping Apoptotic Process RNA Splicing Gene Expression Viral Process PiRNA Metabolic Process Somatic Stem Cell Maintenance Positive Regulation Of Translational Initiation Positive Regulation Of Viral Transcription Positive Regulation Of Nuclear-transcribed MRNA Poly(A) Tail Shortening	Regulation Of Alternative MRNA Splicing, Via Spliceosome Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Protein Phosphorylation Muscle Organ Development Myoblast Fate Determination Skeletal Muscle Tissue Development Cellular Response To Starvation Myotube Cell Development Myotube Differentiation Involved In Skeletal Muscle Regeneration Skeletal Muscle Cell Differentiation Muscle Cell Differentiation Muscle Cell Fate Commitment Positive Regulation Of Skeletal Muscle Tissue Regeneration Regulation Of RNA Splicing Skeletal Muscle Fiber Adaptation Histone H3 Acetylation Histone H4 Acetylation Positive Regulation Of Myoblast Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Skeletal Muscle Fiber Development Positive Regulation Of Skeletal Muscle Fiber Development Positive Regulation Of Muscle Cell Differentiation Cellular Response To Glucocorticoid Stimulus Cellular Response To Estradiol Stimulus Cellular Response To Oxygen Levels Positive Regulation Of Myoblast Fusion
Pathways		RNA Polymerase II Promoter Escape mRNA Splicing Formation of HIV-1 elongation complex containing HIV-1 Tat PIWI-interacting RNA (piRNA) biogenesis Nucleotide Excision Repair RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription Abortive elongation of HIV-1 transcript in the absence of Tat HIV Infection Regulatory RNA pathways Formation of the Early Elongation Complex Tat-mediated elongation of the HIV-1 transcript Tat-mediated HIV elongation arrest and recovery Formation of transcription-coupled NER (TC-NER) repair complex RNA Pol II CTD phosphorylation and interaction with CE RNA Polymerase II Pre-transcription Events Dual incision reaction in TC-NER Influenza Life Cycle HIV elongation arrest and recovery HIV Life Cycle HIV Transcription Initiation Influenza Viral RNA Transcription and Replication RNA Pol II CTD phosphorylation and interaction with CE Transcriptional regulation of pluripotent stem cells RNA Polymerase II HIV Promoter Escape HIV Transcription Elongation POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation Transcriptional regulation by small RNAs Processing of Capped Intron-Containing Pre-mRNA mRNA Capping mRNA Splicing - Minor Pathway mRNA Splicing - Major Pathway MicroRNA (miRNA) biogenesis Influenza Infection Pausing and recovery of Tat-mediated HIV elongation Late Phase of HIV Life Cycle Formation of RNA Pol II elongation complex RNA Polymerase II Transcription Initiation And Promoter Clearance Pausing and recovery of HIV elongation Formation of HIV elongation complex in the absence of HIV Tat Transcription-coupled NER (TC-NER) Viral Messenger RNA Synthesis Formation of the HIV-1 Early Elongation Complex RNA Polymerase II Transcription Initiation Transcription of the HIV genome RNA Polymerase II Transcription Elongation	CDO in myogenesis Myogenesis
Drugs
Diseases
GWAS
Protein-Protein Interactions		21 interactors: ATF7IP DDX54 EWSR1 FNDC4 MCM3AP MYOD1 NOTCH2NL NTRK2 POLR2A POLR2C POLR2D POLR2E POLR2F POLR2H POLR2K POLR2L PRKRA STK19 TAF15 TNNC1 VHL	61 interactors: ASCL3 BHLHA15 BHLHE40 BHLHE41 C2orf88 CALM1 CALM2 CALM3 CARM1 CDC34 CDK2 CDK4 CDKN1C CIB2 CREBBP CSRP3 ELSPBP1 EP300 HAND1 HDAC1 HEY1 HIST1H3A HSP90AA1 ID1 ID2 ID3 ID4 IFRD1 JUN KAT2B KAT5 KPNA3 MDFI MEF2A MEF2C MOS MYOCD NCOR1 NCOR2 NR2F2 PHB2 POLR2G PRKCA PRMT5 PSMD4 PSME2 RB1 RORA RUNX1 RXRA SETD3 SMAD3 SMAD4 SMAD7 SP1 SRF STAT3 SUV39H1 TCF3 TCF4 TWIST1
Entrez ID		5436	4654
HPRD ID		15995	01166
Ensembl ID		ENSG00000168002	ENSG00000129152
Uniprot IDs		P62487	P15172
PDB IDs		2C35
Enriched GO Terms of Interacting Partners?		7-methylguanosine MRNA Capping Transcription Elongation From RNA Polymerase II Promoter PiRNA Metabolic Process 7-methylguanosine RNA Capping Transcription-coupled Nucleotide-excision Repair DNA-templated Transcription, Elongation Positive Regulation Of Viral Transcription Somatic Stem Cell Maintenance Regulation Of Viral Transcription Positive Regulation Of Viral Process Nucleotide-excision Repair Transcription Initiation From RNA Polymerase II Promoter DNA-templated Transcription, Initiation Stem Cell Maintenance Regulation Of Viral Process Termination Of RNA Polymerase III Transcription Transcription Elongation From RNA Polymerase III Promoter Viral Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Processing Termination Of RNA Polymerase I Transcription Stem Cell Development Positive Regulation Of Gene Expression Transcription Elongation From RNA Polymerase I Promoter Transcription Initiation From RNA Polymerase I Promoter Positive Regulation Of Cellular Biosynthetic Process Transcription From RNA Polymerase I Promoter Stem Cell Differentiation RNA Splicing Regulation Of Gene Expression, Epigenetic Positive Regulation Of Macromolecule Biosynthetic Process Transcription From RNA Polymerase III Promoter Transcription From RNA Polymerase II Promoter MRNA Processing NcRNA Metabolic Process Transcription, DNA-templated DNA-templated Transcription, Termination DNA Metabolic Process RNA Biosynthetic Process Negative Regulation Of Gene Expression, Epigenetic Positive Regulation Of Type I Interferon Production MRNA Metabolic Process Cellular Response To Stress Regulation Of Cell Differentiation Positive Regulation Of Cellular Metabolic Process RNA Metabolic Process DNA Repair Regulation Of Gene Expression Regulation Of Type I Interferon Production	Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cellular Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Biosynthetic Process Transcription, DNA-templated Negative Regulation Of Gene Expression RNA Biosynthetic Process Gene Expression Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Metabolic Process Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription From RNA Polymerase II Promoter Nitrogen Compound Metabolic Process Regulation Of RNA Biosynthetic Process Cellular Macromolecule Biosynthetic Process Regulation Of Metabolic Process RNA Metabolic Process Regulation Of RNA Metabolic Process Macromolecule Biosynthetic Process Rhythmic Process Regulation Of Transcription, DNA-templated Regulation Of Gene Expression Regulation Of Nucleic Acid-templated Transcription Organ Development Cellular Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Anatomical Structure Morphogenesis Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Response To Organic Substance Organ Morphogenesis Anatomical Structure Development Cardiovascular System Development Regulation Of Cell Differentiation Heart Development Response To Growth Factor Biosynthetic Process Regulation Of Cell Cycle Developmental Process Cell Differentiation System Development Regulation Of Binding
Tagcloud ?			antitrypsin chn chondrosarcoma desmin desmoplastic ectomesenchymoma etv1 ews extraskeletal fkhr fli1 hhf35 liposarcoma mic2 myxoid p22 pax pnet q12 q14 q22 q24 q35 ssx1 stt stts syt tec witnessed
Tagcloud (Difference) ?			antitrypsin chn chondrosarcoma desmin desmoplastic ectomesenchymoma etv1 ews extraskeletal fkhr fli1 hhf35 liposarcoma mic2 myxoid p22 pax pnet q12 q14 q22 q24 q35 ssx1 stt stts syt tec witnessed
Tagcloud (Intersection) ?