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POLR2G and POLR2E
Number of citations of the paper that reports this interaction (PubMedID
35271311
)
106
Data Source:
BioGRID
(affinity chromatography technology, biochemical)
HPRD
(in vitro)
POLR2G
POLR2E
Description
RNA polymerase II subunit G
RNA polymerase II, I and III subunit E
Image
GO Annotations
Cellular Component
DNA-directed RNA Polymerase Complex
P-body
Nucleus
Nucleoplasm
RNA Polymerase II, Core Complex
DNA-directed RNA Polymerase Complex
Nucleus
Nucleoplasm
RNA Polymerase II, Core Complex
RNA Polymerase III Complex
Nucleolus
RNA Polymerase I Complex
Cytosol
RPAP3/R2TP/prefoldin-like Complex
Molecular Function
Nucleic Acid Binding
Single-stranded DNA Binding
RNA Binding
Single-stranded RNA Binding
Protein Binding
Translation Initiation Factor Binding
DNA Binding
DNA-directed RNA Polymerase Activity
Protein Binding
Biological Process
Nuclear-transcribed MRNA Catabolic Process
DNA-templated Transcription
DNA-templated Transcription Initiation
Transcription By RNA Polymerase II
Transcription Initiation At RNA Polymerase II Promoter
Positive Regulation Of Translational Initiation
Positive Regulation Of Nuclear-transcribed MRNA Poly(A) Tail Shortening
DNA-templated Transcription
Transcription Elongation By RNA Polymerase I
Transcription By RNA Polymerase II
TRNA Transcription By RNA Polymerase III
Protein Stabilization
Pathways
Formation of RNA Pol II elongation complex
Formation of the Early Elongation Complex
Formation of HIV elongation complex in the absence of HIV Tat
Formation of the HIV-1 Early Elongation Complex
RNA Pol II CTD phosphorylation and interaction with CE during HIV infection
HIV Transcription Initiation
RNA Polymerase II HIV Promoter Escape
Transcription of the HIV genome
Formation of HIV-1 elongation complex containing HIV-1 Tat
Formation of HIV-1 elongation complex containing HIV-1 Tat
Pausing and recovery of Tat-mediated HIV elongation
Abortive elongation of HIV-1 transcript in the absence of Tat
Tat-mediated HIV elongation arrest and recovery
Tat-mediated elongation of the HIV-1 transcript
HIV elongation arrest and recovery
Pausing and recovery of HIV elongation
Viral Messenger RNA Synthesis
MicroRNA (miRNA) biogenesis
Transcriptional regulation by small RNAs
PIWI-interacting RNA (piRNA) biogenesis
Activation of anterior HOX genes in hindbrain development during early embryogenesis
RNA Polymerase II Pre-transcription Events
Formation of TC-NER Pre-Incision Complex
Transcription-Coupled Nucleotide Excision Repair (TC-NER)
Dual incision in TC-NER
Gap-filling DNA repair synthesis and ligation in TC-NER
TP53 Regulates Transcription of DNA Repair Genes
FGFR2 alternative splicing
RNA polymerase II transcribes snRNA genes
RNA polymerase II transcribes snRNA genes
mRNA Capping
mRNA Splicing - Major Pathway
mRNA Splicing - Minor Pathway
Processing of Capped Intron-Containing Pre-mRNA
RNA Polymerase II Promoter Escape
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
RNA Polymerase II Transcription Initiation
RNA Polymerase II Transcription Elongation
RNA Polymerase II Transcription Initiation And Promoter Clearance
RNA Pol II CTD phosphorylation and interaction with CE
Signaling by FGFR2 IIIa TM
Estrogen-dependent gene expression
Inhibition of DNA recombination at telomere
Formation of RNA Pol II elongation complex
Formation of the Early Elongation Complex
Formation of HIV elongation complex in the absence of HIV Tat
Formation of the HIV-1 Early Elongation Complex
RNA Pol II CTD phosphorylation and interaction with CE during HIV infection
HIV Transcription Initiation
RNA Polymerase II HIV Promoter Escape
Transcription of the HIV genome
Formation of HIV-1 elongation complex containing HIV-1 Tat
Formation of HIV-1 elongation complex containing HIV-1 Tat
Pausing and recovery of Tat-mediated HIV elongation
Abortive elongation of HIV-1 transcript in the absence of Tat
Tat-mediated HIV elongation arrest and recovery
Tat-mediated elongation of the HIV-1 transcript
HIV elongation arrest and recovery
Pausing and recovery of HIV elongation
Viral Messenger RNA Synthesis
Cytosolic sensors of pathogen-associated DNA
MicroRNA (miRNA) biogenesis
NoRC negatively regulates rRNA expression
B-WICH complex positively regulates rRNA expression
Transcriptional regulation by small RNAs
PIWI-interacting RNA (piRNA) biogenesis
Activation of anterior HOX genes in hindbrain development during early embryogenesis
RNA Polymerase II Pre-transcription Events
Formation of TC-NER Pre-Incision Complex
Transcription-Coupled Nucleotide Excision Repair (TC-NER)
Dual incision in TC-NER
Gap-filling DNA repair synthesis and ligation in TC-NER
TP53 Regulates Transcription of DNA Repair Genes
FGFR2 alternative splicing
RNA polymerase II transcribes snRNA genes
RNA polymerase II transcribes snRNA genes
mRNA Capping
mRNA Splicing - Major Pathway
mRNA Splicing - Minor Pathway
Processing of Capped Intron-Containing Pre-mRNA
RNA Polymerase I Transcription Initiation
RNA Polymerase I Transcription Initiation
RNA Polymerase I Promoter Escape
RNA Polymerase II Promoter Escape
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
RNA Polymerase III Chain Elongation
RNA Polymerase I Transcription Termination
RNA Polymerase III Transcription Termination
RNA Polymerase III Abortive And Retractive Initiation
RNA Polymerase II Transcription Initiation
RNA Polymerase II Transcription Elongation
RNA Polymerase II Transcription Initiation And Promoter Clearance
RNA Polymerase III Transcription Initiation From Type 1 Promoter
RNA Polymerase III Transcription Initiation From Type 1 Promoter
RNA Polymerase III Transcription Initiation From Type 2 Promoter
RNA Polymerase III Transcription Initiation From Type 2 Promoter
RNA Polymerase III Transcription Initiation From Type 3 Promoter
RNA Polymerase III Transcription Initiation From Type 3 Promoter
RNA Pol II CTD phosphorylation and interaction with CE
Signaling by FGFR2 IIIa TM
Estrogen-dependent gene expression
Inhibition of DNA recombination at telomere
Drugs
Diseases
GWAS
Waist-to-hip ratio adjusted for BMI (
26426971
)
Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) (
26426971
)
Cortical amyloid beta load (
29860282
)
Menopause (age at onset) (
26414677
)
Interacting Genes
45 interacting genes:
ATF7IP
BCL2L15
C22orf15
CIB3
CNTNAP2
DDX54
DES
DUSP29
EIF3D
EIF4A3
EWSR1
FNDC4
FOSL2
GPKOW
HOXC5
KIF5B
LMO2
MAPK1
MCM3AP
MCPH1
MYOD1
NOTCH2NLA
NTRK2
OSGIN1
PARVG
POLR1C
POLR2A
POLR2C
POLR2D
POLR2E
POLR2F
POLR2H
PRKRA
PSMB8
RPAP1
TAF15
TNNC1
TRAPPC2L
TRIM14
TRIM68
TSEN15
UPRT
VHL
WHR1
ZNF410
29 interacting genes:
CHGB
FKBP14
FOS
GTF2F2
HSP90B1
IKBKG
IP6K3
ITCH
LZTR1
NEDD4
PML
POLR2A
POLR2C
POLR2D
POLR2F
POLR2G
POLR2H
POLR2K
POLR2L
SRPK1
SYT5
TAF15
TRIM29
TRIM55
TRIM63
UBE2D1
UBE2D4
URI1
ZSCAN1
Entrez ID
5436
5434
HPRD ID
15995
15946
Ensembl ID
ENSG00000168002
ENSG00000099817
Uniprot IDs
P62487
B4DJ89
E5KT65
P19388
PDB IDs
2C35
5IY6
5IY7
5IY8
5IY9
5IYA
5IYB
5IYC
5IYD
6DRD
6O9L
6XRE
7LBM
9EHZ
9EI1
9EI3
9EI4
5IY6
5IY7
5IY8
5IY9
5IYA
5IYB
5IYC
5IYD
6DRD
6O9L
6XRE
7A6H
7AE1
7AE3
7AEA
7AST
7D58
7D59
7DN3
7DU2
7FJI
7FJJ
7LBM
7OB9
7OBA
7OBB
7VBA
7VBB
7VBC
8A43
8ITY
8IUE
8IUH
9EHZ
9EI1
9EI3
9EI4
9FSO
9FSP
9FSQ
9FSR
9FSS
Enriched GO Terms of Interacting Partners
?
DNA-directed RNA Polymerase Complex
RNA Polymerase II, Core Complex
DNA-directed RNA Polymerase Activity
RNA Polymerase I Complex
RNA Polymerase III Complex
Nucleoplasm
Transcription By RNA Polymerase II
DNA-templated Transcription
Nucleus
Cerebral Cortex Development
Nucleolus
RNA Metabolic Process
Nucleobase-containing Compound Biosynthetic Process
Nucleic Acid Binding
Cellular Response To Brain-derived Neurotrophic Factor Stimulus
Outer Ear Morphogenesis
Macromolecule Biosynthetic Process
Transcription Coregulator Activity
TRNA Transcription By RNA Polymerase III
TRNA Transcription
Contractile Muscle Fiber
Macromolecule Metabolic Process
Nucleic Acid Metabolic Process
Nucleobase-containing Compound Metabolic Process
Striatum Development
Transcription By RNA Polymerase I
DNA Binding
RNA Polymerase II, Core Complex
DNA-directed RNA Polymerase Complex
Transcription By RNA Polymerase II
DNA-templated Transcription
DNA-directed RNA Polymerase Activity
RNA Polymerase I Complex
RNA Polymerase III Complex
Nucleobase-containing Compound Biosynthetic Process
RNA Metabolic Process
Macromolecule Metabolic Process
Macromolecule Biosynthetic Process
Nucleus
Protein K63-linked Ubiquitination
Nucleoplasm
Innate Immune Response
Transcription By RNA Polymerase III
Regulation Of Nucleobase-containing Compound Metabolic Process
Protein Modification By Small Protein Conjugation
Nucleic Acid Metabolic Process
Protein K48-linked Ubiquitination
Regulation Of RNA Metabolic Process
Defense Response To Symbiont
Defense Response To Other Organism
Transcription Initiation At RNA Polymerase II Promoter
Response To External Biotic Stimulus
Ubiquitin-protein Transferase Activity
Protein Ubiquitination
Post-translational Protein Modification
Protein Polyubiquitination
Response To Other Organism
TRNA Transcription By RNA Polymerase III
TRNA Transcription
Protein K29-linked Ubiquitination
Regulation Of DNA-templated Transcription
Regulation Of RNA Biosynthetic Process
DNA Binding
DNA-templated Transcription Initiation
Transcription By RNA Polymerase I
Regulation Of Primary Metabolic Process
Nucleobase-containing Compound Metabolic Process
Ubiquitin Protein Ligase Activity
Protein Modification Process
Defense Response
Translation Initiation Factor Binding
Regulation Of Gene Expression
SMAD Protein Signal Transduction
Transferase Activity
Regulation Of Macromolecule Biosynthetic Process
Medium-term Memory
Cellular Response To Prolactin
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Tagcloud (Difference)
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Tagcloud (Intersection)
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