HOXC9 and HOXC13

Number of citations of the paper that reports this interaction (PubMedID 20211142)
41

Data Source:
BioGRID (two hybrid)

		HOXC9	HOXC13
Description		homeobox C9	homeobox C13
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Aggresome Transcription Repressor Complex	Chromatin Nucleus
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific Double-stranded DNA Binding	Transcription Cis-regulatory Region Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Chromatin Binding DNA-binding Transcription Factor Activity Protein Binding DNA-binding Transcription Factor Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	DNA-templated Transcription Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Anterior/posterior Pattern Specification Proximal/distal Pattern Formation Negative Regulation Of Cell Cycle Embryonic Skeletal System Morphogenesis Embryonic Skeletal System Development	Hair Follicle Development Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Anatomical Structure Morphogenesis Anterior/posterior Pattern Specification Nail Development Tongue Morphogenesis Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs
Diseases
GWAS		A body shape index ( 34021172) Heel bone mineral density ( 30598549) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 26426971 34021172) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	A body shape index ( 34021172) Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs) ( 23648065) Amyotrophic lateral sclerosis (sporadic) ( 24529757) Biliary atresia ( 20460270) Blond vs. brown/black hair color ( 30531825) Hair shape ( 29220522) Hip circumference adjusted for BMI ( 34021172) Toenail selenium levels ( 25343990) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-hip ratio ( 20935629 25673412) Waist-to-hip ratio adjusted for BMI ( 34021172 26426971) Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction) ( 28448500) Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625) Waist-to-hip ratio adjusted for BMI in active individuals ( 28448500) Waist-to-hip ratio adjusted for BMI in non-smokers ( 28443625) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971) Waist-to-hip ratio adjusted for body mass index ( 28448500 25673412)
Interacting Genes		29 interacting genes: CBX6 CYSRT1 ELAVL2 GMNN GTF2A1L HOXC13 HOXD1 HOXD9 IRF9 KRTAP6-2 LPXN MAGED1 MSX2 NFKBID NMI PAX6 PAX8 PBX2 PCGF2 POLR2D POLR3D POU2AF1 POU2F1 SPMIP9 TLE5 UFSP1 ZFP36 ZMYND12 ZNF384	7 interacting genes: APEX1 ELF1 HNRNPAB HOXC9 MEIS1 NR2E3 RHOXF2
Entrez ID		3225	3229
HPRD ID		00857	00862
Ensembl ID		ENSG00000180806	ENSG00000123364
Uniprot IDs		P31274	P31276
PDB IDs		2LP0 2MSY
Enriched GO Terms of Interacting Partners?		Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression Chromatin Regulation Of Macromolecule Biosynthetic Process Regulation Of RNA Metabolic Process DNA Binding Regionalization Regulation Of Transcription By RNA Polymerase II Regulation Of Nucleobase-containing Compound Metabolic Process Nucleus Regulation Of Macromolecule Metabolic Process Pattern Specification Process Sequence-specific Double-stranded DNA Binding DNA-templated Transcription Regulation Of Metabolic Process Regulation Of Primary Metabolic Process Anterior/posterior Pattern Specification DNA-binding Transcription Factor Activity Chromatin Binding Animal Organ Morphogenesis Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Negative Regulation Of RNA Metabolic Process Embryonic Morphogenesis Transcription Cis-regulatory Region Binding Positive Regulation Of RNA Metabolic Process Embryonic Skeletal System Development Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Epithelial Cell Differentiation Negative Regulation Of Transcription By RNA Polymerase II RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Positive Regulation Of Nucleobase-containing Compound Metabolic Process Skeletal System Development Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Biosynthetic Process Embryonic Limb Morphogenesis PRC1 Complex Positive Regulation Of Branching Involved In Ureteric Bud Morphogenesis Nucleobase-containing Compound Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Macromolecule Biosynthetic Process RNA Polymerase II Core Promoter Sequence-specific DNA Binding Regulation Of Branching Involved In Ureteric Bud Morphogenesis Negative Regulation Of Biosynthetic Process Positive Regulation Of Biosynthetic Process Limb Morphogenesis Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Macromolecule Metabolic Process	Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of RNA Metabolic Process DNA Binding Chromatin Sequence-specific Double-stranded DNA Binding Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Biosynthetic Process Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Regulation Of Gene Expression Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of RNA Metabolic Process Positive Regulation Of Metabolic Process Phosphodiesterase Activity, Acting On 3'-phosphoglycolate-terminated DNA Strands Class II DNA-(apurinic Or Apyrimidinic Site) Endonuclease Activity Positive Regulation Of Nucleobase-containing Compound Metabolic Process Telomere Maintenance Via Base-excision Repair Regulation Of Macromolecule Metabolic Process RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Regulation Of Metabolic Process Sequence-specific DNA Binding DNA-(abasic Site) Binding Double-stranded DNA Exodeoxyribonuclease Activity Deoxyribonuclease (pyrimidine Dimer) Activity Positive Regulation Of Gene Expression Positive Regulation Of Transcription By RNA Polymerase II Nucleus Uracil DNA N-glycosylase Activity MRNA Editing Complex DNA-binding Transcription Factor Activity Phosphodiesterase I Activity Cellular Developmental Process Chromosomal 5-methylcytosine DNA Demethylation Pathway Neuron Development Double-stranded DNA 3'-5' DNA Exonuclease Activity Regulation Of Intracellular MRNA Localization Neuronal Ribonucleoprotein Granule RNA-DNA Hybrid Ribonuclease Activity Double-stranded Telomeric DNA Binding Developmental Process Negative Regulation Of Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Cell Growth Involved In Cardiac Muscle Cell Development 3'-5'-DNA Exonuclease Activity
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?