HOXC9 and POLR3D

Number of citations of the paper that reports this interaction (PMID 20211142)
148

Data Source:
BioGRID (two hybrid)

		HOXC9	POLR3D
Gene Name		homeobox C9	polymerase (RNA) III (DNA directed) polypeptide D, 44kDa
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Nuclear Chromatin Nucleoplasm DNA-directed RNA Polymerase III Complex Cytoplasm Cytosol
	Molecular Function	Sequence-specific DNA Binding	RNA Polymerase III Activity DNA Binding Chromatin Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Anterior/posterior Pattern Specification Embryonic Skeletal System Morphogenesis	Transcription From RNA Polymerase III Promoter Transcription Elongation From RNA Polymerase III Promoter Termination Of RNA Polymerase III Transcription Gene Expression Positive Regulation Of Type I Interferon Production Positive Regulation Of Interferon-beta Production Innate Immune Response Positive Regulation Of Innate Immune Response Defense Response To Virus
Pathways			RNA Polymerase III Transcription Termination RNA Polymerase III Transcription RNA Polymerase III Transcription Initiation RNA Polymerase III Transcription Initiation From Type 3 Promoter RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription RNA Polymerase III Abortive And Retractive Initiation Cytosolic sensors of pathogen-associated DNA RNA Polymerase III Chain Elongation RNA Polymerase III Transcription Initiation From Type 2 Promoter Innate Immune System
Drugs
Diseases
GWAS			Hypertriglyceridemia ( 23505323)
Protein-Protein Interactions		16 interactors: CBX6 ELAVL2 GMNN GTF2A1L HOXC13 HOXD1 HOXD9 IRF9 LPXN NMI PCGF2 POLR2D POLR3D POU2F1 ZFP36 ZNF384	13 interactors: APEX1 ATF3 HNRNPAB HOXA10 HOXC9 MAPK11 MSX2 NR2E3 POLR3E RBFOX2 RHOXF2 TAB1 ZNF496
Entrez ID		3225	661
HPRD ID		00857	01755
Ensembl ID		ENSG00000180806	ENSG00000168495
Uniprot IDs		P31274 Q8N561	P05423
PDB IDs		2LP0
Enriched GO Terms of Interacting Partners?		Transcription, DNA-templated RNA Biosynthetic Process RNA Metabolic Process Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Nucleic Acid-templated Transcription Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Regulation Of Gene Expression Cellular Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Transcription From RNA Polymerase II Promoter Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Embryonic Skeletal System Development Regulation Of Cellular Process Cellular Metabolic Process Positive Regulation Of Gene Expression Organ Morphogenesis Transcription From RNA Polymerase III Promoter Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Anterior/posterior Pattern Specification Recruitment Of 3'-end Processing Factors To RNA Polymerase II Holoenzyme Complex MRNA 3'-end Processing MRNA Export From Nucleus In Response To Heat Stress Negative Regulation Of Transcription From RNA Polymerase II Promoter DNA-templated Transcription, Elongation Negative Regulation Of Cellular Metabolic Process RNA 3'-end Processing Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Embryonic Skeletal System Morphogenesis Pattern Specification Process Negative Regulation Of B Cell Receptor Signaling Pathway Olfactory Placode Formation Positive Regulation Of Transcription From RNA Polymerase II Promoter Nuclear-transcribed MRNA Catabolic Process Positive Regulation Of Cellular Metabolic Process	Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Transcription, DNA-templated RNA Metabolic Process RNA Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Gene Expression Negative Regulation Of Biosynthetic Process Regulation Of Metabolic Process Nucleobase-containing Compound Metabolic Process Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Cellular Metabolic Process Cellular Macromolecule Biosynthetic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Macromolecule Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Gene Expression Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Cellular Metabolic Process Organ Development Developmental Process Nitrogen Compound Metabolic Process Transcription From RNA Polymerase II Promoter Anatomical Structure Morphogenesis Positive Regulation Of Metabolic Process Intracellular Receptor Signaling Pathway Biosynthetic Process Anatomical Structure Development Regulation Of Transcription From RNA Polymerase II Promoter Cellular Response To Organic Substance Anterior/posterior Pattern Specification Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Epithelial To Mesenchymal Transition Positive Regulation Of Transcription, DNA-templated Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway System Development Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Tagcloud ?		acquisition addressed attenuation chip coordinated coordinates differentiation diverse downregulation e2f6 exit global interacted mapping microarray neuroblastoma neuronal profiling promoters question recruited remarkably repressing repressor seq sets specialized upregulation wide	address ago1 antisense argonaute cis cytoplasm directed directs encoded existence h3k27me3 interference micrornas mir mirna mirnas orientation pcg polycomb posttranscriptional proximal rnai searched silence silencing start tgs transcriptionally tri
Tagcloud (Difference) ?		acquisition addressed attenuation chip coordinated coordinates differentiation diverse downregulation e2f6 exit global interacted mapping microarray neuroblastoma neuronal profiling promoters question recruited remarkably repressing repressor seq sets specialized upregulation wide	address ago1 antisense argonaute cis cytoplasm directed directs encoded existence h3k27me3 interference micrornas mir mirna mirnas orientation pcg polycomb posttranscriptional proximal rnai searched silence silencing start tgs transcriptionally tri
Tagcloud (Intersection) ?