HOXC9 and HOXD9

Number of citations of the paper that reports this interaction (PMID 20211142)
148

Data Source:
BioGRID (two hybrid)

		HOXC9	HOXD9
Gene Name		homeobox C9	homeobox D9
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Nucleus
	Molecular Function	Sequence-specific DNA Binding	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Negative Regulation Of Transcription
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Anterior/posterior Pattern Specification Embryonic Skeletal System Morphogenesis	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Single Fertilization Skeletal Muscle Tissue Development Adult Locomotory Behavior Anterior/posterior Pattern Specification Proximal/distal Pattern Formation Mammary Gland Development Embryonic Forelimb Morphogenesis Hindlimb Morphogenesis Positive Regulation Of Transcription From RNA Polymerase II Promoter Embryonic Skeletal System Morphogenesis Peripheral Nervous System Neuron Development
Pathways
Drugs
Diseases
GWAS			Magnesium levels ( 20700443)
Protein-Protein Interactions		16 interactors: CBX6 ELAVL2 GMNN GTF2A1L HOXC13 HOXD1 HOXD9 IRF9 LPXN NMI PCGF2 POLR2D POLR3D POU2F1 ZFP36 ZNF384	9 interactors: BARX1 ETV5 FAIM3 GORAB HMGB1 HOXC9 MEIS1 PBX1 PKNOX1
Entrez ID		3225	3235
HPRD ID		00857	00865
Ensembl ID		ENSG00000180806
Uniprot IDs		P31274 Q8N561	P28356
PDB IDs		2LP0
Enriched GO Terms of Interacting Partners?		Transcription, DNA-templated RNA Biosynthetic Process RNA Metabolic Process Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Nucleic Acid-templated Transcription Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Regulation Of Gene Expression Cellular Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Transcription From RNA Polymerase II Promoter Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Embryonic Skeletal System Development Regulation Of Cellular Process Cellular Metabolic Process Positive Regulation Of Gene Expression Organ Morphogenesis Transcription From RNA Polymerase III Promoter Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Anterior/posterior Pattern Specification Recruitment Of 3'-end Processing Factors To RNA Polymerase II Holoenzyme Complex MRNA 3'-end Processing MRNA Export From Nucleus In Response To Heat Stress Negative Regulation Of Transcription From RNA Polymerase II Promoter DNA-templated Transcription, Elongation Negative Regulation Of Cellular Metabolic Process RNA 3'-end Processing Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Embryonic Skeletal System Morphogenesis Pattern Specification Process Negative Regulation Of B Cell Receptor Signaling Pathway Olfactory Placode Formation Positive Regulation Of Transcription From RNA Polymerase II Promoter Nuclear-transcribed MRNA Catabolic Process Positive Regulation Of Cellular Metabolic Process	Immune System Development Positive Regulation Of Transcription From RNA Polymerase II Promoter Immune System Process Transcription, DNA-templated RNA Biosynthetic Process Positive Regulation Of Transcription, DNA-templated System Development Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of RNA Biosynthetic Process Positive Regulation Of Gene Expression Regulation Of RNA Metabolic Process Anterior/posterior Pattern Specification Positive Regulation Of Cellular Biosynthetic Process Nucleobase-containing Compound Metabolic Process Spleen Development Multicellular Organismal Development Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Gene Expression Anatomical Structure Development Transcription From RNA Polymerase II Promoter Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Cellular Nitrogen Compound Metabolic Process RNA Metabolic Process Cell Differentiation Gene Expression Developmental Process Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Negative Regulation Of Apoptotic Cell Clearance Pattern Specification Process Regulation Of Neuron Differentiation Positive Regulation Of Cellular Metabolic Process Skeletal System Development Negative Regulation Of RNA Polymerase II Transcriptional Preinitiation Complex Assembly Hemopoiesis Generation Of Neurons Regulation Of Neurogenesis Embryonic Skeletal System Development Organ Development Negative Regulation Of DNA-templated Transcription, Initiation Negative Regulation Of Transcription Initiation From RNA Polymerase II Promoter Neurogenesis Biosynthetic Process Base-excision Repair, DNA Ligation Male Germ-line Stem Cell Asymmetric Division
Tagcloud ?		acquisition addressed attenuation chip coordinated coordinates differentiation diverse downregulation e2f6 exit global interacted mapping microarray neuroblastoma neuronal profiling promoters question recruited remarkably repressing repressor seq sets specialized upregulation wide	aberrantly aberration adjacent autosomal beadchips bisulfite cholangiocarcinogenesis cholangiocarcinoma cpg eed epigenetically epigenomic false homeobox hoxa9 humanmethylation27 hypermethylated hypermethylation hypomethylated infinium methylomes ontology prc2 profiled pyrosequencing representing sets suz12 trimethylation
Tagcloud (Difference) ?		acquisition addressed attenuation chip coordinated coordinates differentiation diverse downregulation e2f6 exit global interacted mapping microarray neuroblastoma neuronal profiling promoters question recruited remarkably repressing repressor seq specialized upregulation wide	aberrantly aberration adjacent autosomal beadchips bisulfite cholangiocarcinogenesis cholangiocarcinoma cpg eed epigenetically epigenomic false homeobox hoxa9 humanmethylation27 hypermethylated hypermethylation hypomethylated infinium methylomes ontology prc2 profiled pyrosequencing representing suz12 trimethylation
Tagcloud (Intersection) ?		sets