HOXC9 and POU2F1

Number of citations of the paper that reports this interaction (PMID 20211142)
148

Data Source:
BioGRID (two hybrid)

		HOXC9	POU2F1
Gene Name		homeobox C9	POU class 2 homeobox 1
Image
Gene Ontology Annotations	Cellular Component	Nucleus	Nucleus Nucleoplasm Transcription Factor Complex Intracellular Membrane-bounded Organelle
	Molecular Function	Sequence-specific DNA Binding	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Anterior/posterior Pattern Specification Embryonic Skeletal System Morphogenesis	Transcription From RNA Polymerase III Promoter Gene Expression Olfactory Placode Formation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Lens Induction In Camera-type Eye
Pathways			RNA Polymerase III Transcription RNA Polymerase III Transcription Initiation RNA Polymerase III Transcription Initiation From Type 3 Promoter RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription RNA Polymerase III Abortive And Retractive Initiation
Drugs
Diseases
GWAS			Liver enzyme levels ( 18940312)
Protein-Protein Interactions		16 interactors: CBX6 ELAVL2 GMNN GTF2A1L HOXC13 HOXD1 HOXD9 IRF9 LPXN NMI PCGF2 POLR2D POLR3D POU2F1 ZFP36 ZNF384	50 interactors: AES APP AR BARD1 BRCA1 CEBPE CREB1 EPRS ESR1 FDXR HCFC1 HMGA1 HMGB2 HNF1A HOXB13 HOXC9 IRF9 LIFR MNAT1 MSX1 NCOR2 NFYA NPAT NR3C1 PARP1 PBX1 PGR PKNOX1 PLK3 POGZ POU2AF1 PRKACA PRKDC RARA RELA RXRA SNAPC4 SOX2 SP1 SP4 STAT5A STAT5B TBP THRA TLE4 TLX2 TNF TXNRD1 VDR XRCC6
Entrez ID		3225	5451
HPRD ID		00857	01250
Ensembl ID		ENSG00000180806	ENSG00000143190
Uniprot IDs		P31274 Q8N561	J3KP77 P14859
PDB IDs		2LP0	1CQT 1E3O 1GT0 1HF0 1O4X 1OCT 1POG 1POU
Enriched GO Terms of Interacting Partners?		Transcription, DNA-templated RNA Biosynthetic Process RNA Metabolic Process Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Nucleic Acid-templated Transcription Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Regulation Of Gene Expression Cellular Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Transcription From RNA Polymerase II Promoter Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Embryonic Skeletal System Development Regulation Of Cellular Process Cellular Metabolic Process Positive Regulation Of Gene Expression Organ Morphogenesis Transcription From RNA Polymerase III Promoter Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Anterior/posterior Pattern Specification Recruitment Of 3'-end Processing Factors To RNA Polymerase II Holoenzyme Complex MRNA 3'-end Processing MRNA Export From Nucleus In Response To Heat Stress Negative Regulation Of Transcription From RNA Polymerase II Promoter DNA-templated Transcription, Elongation Negative Regulation Of Cellular Metabolic Process RNA 3'-end Processing Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Embryonic Skeletal System Morphogenesis Pattern Specification Process Negative Regulation Of B Cell Receptor Signaling Pathway Olfactory Placode Formation Positive Regulation Of Transcription From RNA Polymerase II Promoter Nuclear-transcribed MRNA Catabolic Process Positive Regulation Of Cellular Metabolic Process	Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cellular Biosynthetic Process RNA Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Regulation Of RNA Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Gene Expression RNA Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Macromolecule Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Nitrogen Compound Metabolic Process Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Gland Development Negative Regulation Of Gene Expression Regulation Of Metabolic Process Positive Regulation Of Metabolic Process Negative Regulation Of Biosynthetic Process Transcription Initiation From RNA Polymerase II Promoter Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Organ Development Response To Organic Substance Negative Regulation Of Cellular Metabolic Process Response To Hormone DNA-templated Transcription, Initiation Cellular Metabolic Process Negative Regulation Of Transcription, DNA-templated Cellular Response To Organic Substance Response To Steroid Hormone Organ Morphogenesis Reproductive Process Hormone-mediated Signaling Pathway Anatomical Structure Morphogenesis Intracellular Receptor Signaling Pathway Multicellular Organismal Development System Development
Tagcloud ?		acquisition addressed attenuation chip coordinated coordinates differentiation diverse downregulation e2f6 exit global interacted mapping microarray neuroblastoma neuronal profiling promoters question recruited remarkably repressing repressor seq sets specialized upregulation wide	build built compendium connected controlling databases delineate deoxyribonuclease encode experimentally footprinting gata3 hnf1b hypersensitivity klf4 locations matrices motifs orthologs rarb runx2 rxra silico smad3 sp1 sp3 umod upstream uromodulin
Tagcloud (Difference) ?		acquisition addressed attenuation chip coordinated coordinates differentiation diverse downregulation e2f6 exit global interacted mapping microarray neuroblastoma neuronal profiling promoters question recruited remarkably repressing repressor seq sets specialized upregulation wide	build built compendium connected controlling databases delineate deoxyribonuclease encode experimentally footprinting gata3 hnf1b hypersensitivity klf4 locations matrices motifs orthologs rarb runx2 rxra silico smad3 sp1 sp3 umod upstream uromodulin
Tagcloud (Intersection) ?