DST and ITGB4

Number of citations of the paper that reports this interaction (PMID 14668477)
26

Data Source:
HPRD (two hybrid, in vivo)

		DST	ITGB4
Gene Name		dystonin	integrin, beta 4
Image
Gene Ontology Annotations	Cellular Component	Basement Membrane Nucleus Nuclear Envelope Cytoplasm Endoplasmic Reticulum Membrane Cytosol Intermediate Filament Focal Adhesion Cell Cortex Basal Plasma Membrane Actin Cytoskeleton Microtubule Cytoskeleton Integral Component Of Membrane Cytoplasmic Membrane-bounded Vesicle Z Disc Hemidesmosome Axon Cell Leading Edge H Zone Microtubule Plus-end Intermediate Filament Cytoskeleton Extracellular Vesicular Exosome	Basement Membrane Plasma Membrane Integrin Complex Basal Plasma Membrane Cell Surface Hemidesmosome Cell Leading Edge Receptor Complex Extracellular Vesicular Exosome
	Molecular Function	Actin Binding Integrin Binding Calcium Ion Binding Protein Binding Protein C-terminus Binding Protein Homodimerization Activity Microtubule Plus-end Binding	G-protein Coupled Receptor Binding Receptor Activity Protein Binding
	Biological Process	Microtubule Cytoskeleton Organization Cytoskeleton Organization Cell Cycle Arrest Cell Adhesion Integrin-mediated Signaling Pathway Response To Wounding Maintenance Of Cell Polarity Extracellular Matrix Organization Hemidesmosome Assembly Intermediate Filament Cytoskeleton Organization Cell Motility	Autophagy Cell Adhesion Cell-matrix Adhesion Integrin-mediated Signaling Pathway Response To Wounding Extracellular Matrix Organization Hemidesmosome Assembly Cell Junction Assembly Nail Development Skin Development Filopodium Assembly Mesodermal Cell Differentiation Digestive Tract Development Cell Motility Renal System Development Amelogenesis
Pathways		Cell junction organization Type I hemidesmosome assembly	Cell junction organization Syndecan interactions Type I hemidesmosome assembly Collagen formation Laminin interactions Non-integrin membrane-ECM interactions Assembly of collagen fibrils and other multimeric structures
Drugs
Diseases
GWAS
Protein-Protein Interactions		26 interactors: APC CALM1 CDC5L CELSR3 CEP63 COL17A1 DCTN1 DISC1 DTNBP1 ERBB2IP EXOC1 ITGB4 ITSN2 KIAA0368 KIAA1549 KRT14 KRT5 MAPK6 NFYC PAK2 PRKAB2 PRKD2 SH3BP5 SMAD9 TNIK TRAF3IP1	23 interactors: ALOX12 ATXN1 CLCA1 CLCA2 COL17A1 DST EIF6 ERBB2 ERBB2IP FYN GRB2 ITGA6 MET PLEC PRKCA PRKCD PTK2 SHC1 SREBF2 VIM YES1 YWHAB YWHAQ
Entrez ID		667	3691
HPRD ID		00222	00946
Ensembl ID		ENSG00000151914	ENSG00000132470
Uniprot IDs		B4DGY0 B4DSS9 Q03001 Q6P0N6	P16144
PDB IDs		3GJO	1QG3 2YRZ 3F7P 3F7Q 3F7R 3FQ4 3FSO 3H6A
Enriched GO Terms of Interacting Partners?		Hemidesmosome Assembly Cell-substrate Junction Assembly Cell Junction Assembly Signaling Organelle Organization Cell Communication Signal Transduction Regulation Of Protein Kinase Activity Regulation Of Protein Phosphorylation Intracellular Signal Transduction Regulation Of Kinase Activity Anatomical Structure Development Regulation Of Phosphorylation Cell Cycle Nervous System Development Developmental Process Cellular Component Assembly Regulation Of Phosphorus Metabolic Process Movement Of Cell Or Subcellular Component Epithelium Development Regulation Of Cellular Protein Metabolic Process Microtubule-based Process Cytoskeleton Organization Response To Stimulus Cell Projection Organization Cell Surface Receptor Signaling Pathway Cellular Response To Stimulus Epidermis Development Vascular Endothelial Growth Factor Receptor Signaling Pathway Positive Regulation Of Protein Metabolic Process Regulation Of Protein Metabolic Process Cell Projection Assembly Tissue Development Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Protein Modification Process Positive Regulation Of Metabolic Process Negative Regulation Of Protein Phosphorylation Microtubule-based Transport Cytoskeleton-dependent Intracellular Transport System Development Regulation Of Catalytic Activity Cellular Localization Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Negative Regulation Of Phosphorylation Positive Regulation Of Protein Phosphorylation Positive Regulation Of Cellular Protein Metabolic Process Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Cell Adhesion Regulation Of Signal Transduction	Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Cell-cell Adhesion Fc Receptor Signaling Pathway Movement Of Cell Or Subcellular Component Fibroblast Growth Factor Receptor Signaling Pathway Response To Wounding Cellular Response To Fibroblast Growth Factor Stimulus Hemidesmosome Assembly Response To Fibroblast Growth Factor Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Immune Response-regulating Cell Surface Receptor Signaling Pathway Cellular Response To Growth Factor Stimulus Regulation Of Body Fluid Levels Response To Growth Factor Wound Healing Regulation Of Cell Adhesion Peptidyl-tyrosine Phosphorylation Blood Coagulation Hemostasis Locomotion Immune Response-regulating Signaling Pathway Platelet Activation Protein Autophosphorylation Innate Immune Response Vascular Endothelial Growth Factor Receptor Signaling Pathway Positive Regulation Of Cell Adhesion Chemotaxis Axon Guidance Leukocyte Migration Cell Motility Positive Regulation Of Signal Transduction Cell Surface Receptor Signaling Pathway Regulation Of Phosphorylation Apoptotic Process Cell-substrate Junction Assembly Regulation Of Cell Activation Programmed Cell Death Cell Death Death Cellular Response To Peptide Hormone Stimulus Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Cellular Response To Organic Substance Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Regulation Of Platelet Aggregation Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway
Tagcloud ?		125i alanine amines analogous asked attach attached attaches attempted b2 bradykinin bromide covalently cyanogen disuccinimidyl epsilon exchanged homobifunctional immunoidentification k174a labeling linker lys172 lys174 reacts reagent tartarate tyr8 worked	bag1 bcl2l2 bctis ccna2 comprehend ctsb deregulations fgf1 fosl1 gabrp gsn hnepi id2 il6r klf5 klk5 map2k7 microdissected ngfb ngfr ontological pappa plau scgb1d2 scgb2a1 serpinb5 serpine1 thbs1 thbs2
Tagcloud (Difference) ?		125i alanine amines analogous asked attach attached attaches attempted b2 bradykinin bromide covalently cyanogen disuccinimidyl epsilon exchanged homobifunctional immunoidentification k174a labeling linker lys172 lys174 reacts reagent tartarate tyr8 worked	bag1 bcl2l2 bctis ccna2 comprehend ctsb deregulations fgf1 fosl1 gabrp gsn hnepi id2 il6r klf5 klk5 map2k7 microdissected ngfb ngfr ontological pappa plau scgb1d2 scgb2a1 serpinb5 serpine1 thbs1 thbs2
Tagcloud (Intersection) ?