SLC2A13 and RIC8A

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SLC2A13	RIC8A
Description		solute carrier family 2 member 13	RIC8 guanine nucleotide exchange factor A
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Lysosome Early Endosome Golgi Apparatus Plasma Membrane Synaptic Vesicle Membrane Apical Plasma Membrane Growth Cone Organelle Membrane Cell Projection Intracellular Membrane-bounded Organelle Cell Body Cell Periphery Astrocyte End-foot	Cytoplasm Plasma Membrane Cell Cortex Membrane
	Molecular Function	Protease Binding Myo-inositol Transmembrane Transporter Activity Myo-inositol:proton Symporter Activity Protein Binding Transmembrane Transporter Activity ATPase Binding	G-protein Alpha-subunit Binding Guanyl-nucleotide Exchange Factor Activity Protein Binding Protein Folding Chaperone
	Biological Process	Myo-inositol Transport Transmembrane Transport Transport Across Blood-brain Barrier Positive Regulation Of Amyloid-beta Formation	In Utero Embryonic Development Vasculature Development Protein Folding G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway Gastrulation Visual Learning Response To Light Stimulus Cell Migration Involved In Gastrulation Cell-cell Adhesion Involved In Gastrulation Basement Membrane Organization
Pathways		Inositol transporters
Drugs
Diseases
GWAS		Alzheimer's disease in hypertension ( 31055733) Coronary artery calcification ( 23870195) Crohn's disease ( 28067908) Daytime sleep phenotypes ( 27126917) Disability (impaired activities of daily living) ( 31707593) Inflammatory bowel disease ( 28067908) Insomnia ( 23728906) Parkinson's disease ( 22451204 28011712 32201043) Putamen volume ( 31530798) Sleep quality ( 23728906)	Cataracts ( 34127677) Cataracts (operation) ( 31816047) Gynecologic disease ( 31488892) Gynecologic disease (multivariate analysis) ( 31488892) Mean corpuscular hemoglobin concentration ( 29403010) Meningioma ( 29762745) Platelet count ( 24026423) Uterine fibroids ( 21460842 31488892 31649266) Uterine fibroids (MTAG) ( 31488892)
Interacting Genes		4 interacting genes: CYP4F2 FXYD6-FXYD2 PLP2 RIC8A	27 interacting genes: ATP1A4 EFEMP1 GNA13 GNAI1 GNAI2 GNAI3 GNAO1 GNAQ GNAS MAPK8IP3 MID1 NECAB2 NUTM1 OGT PACSIN2 PDE4B RABAC1 SDCBP SH3GLB1 SLC2A13 TERF1 TUBB2A UBQLN1 UBQLN4 XPO1 ZDHHC17 ZNF585B
Entrez ID		114134	60626
HPRD ID		15363	12373
Ensembl ID		ENSG00000151229	ENSG00000177963
Uniprot IDs		Q96QE2	Q9NPQ8
PDB IDs
Enriched GO Terms of Interacting Partners?		Alpha-tocopherol Omega-hydroxylase Activity Negative Regulation Of Icosanoid Secretion Leukotriene B4 Catabolic Process 20-hydroxy-leukotriene B4 Omega Oxidase Activity Alkane 1-monooxygenase Activity 20-aldehyde-leukotriene B4 20-monooxygenase Activity Leukotriene B4 Metabolic Process Arachidonate Omega-hydroxylase Activity Coagulation Blood Coagulation Hemostasis Leukotriene-B4 20-monooxygenase Activity Pressure Natriuresis Cell-cell Adhesion Involved In Gastrulation Positive Regulation Of Potassium Ion Export Across Plasma Membrane Activation Of Blood Coagulation Via Clotting Cascade Calcium Activated Phosphatidylserine Scrambling Calcium Activated Phospholipid Scrambling Calcium Activated Phosphatidylcholine Scrambling Phosphatidylserine Exposure On Blood Platelet Phylloquinone Catabolic Process Long-chain Fatty Acid Omega-hydroxylase Activity Vitamin K Catabolic Process Vitamin E Metabolic Process Menaquinone Metabolic Process Fatty Acid Omega-oxidation Menaquinone Catabolic Process Negative Regulation Of Cell Volume Chemokine Binding Long-chain Fatty Acid Catabolic Process Negative Regulation Of Fatty Acid Transport Arachidonate Epoxygenase Activity Regulation Of Body Fluid Levels Omega-hydroxylase P450 Pathway Voltage-gated Chloride Channel Activity Bleb Assembly Calcium-activated Cation Channel Activity Voltage-gated Monoatomic Ion Channel Activity Monoatomic Ion Transmembrane Transporter Activity Epoxygenase P450 Pathway Vitamin K Metabolic Process Oxidoreductase Activity, Acting On Paired Donors, With Incorporation Or Reduction Of Molecular Oxygen, NAD(P)H As One Donor, And Incorporation Of One Atom Of Oxygen Cell Migration Involved In Gastrulation Regulation Of Potassium Ion Export Across Plasma Membrane Positive Regulation Of Phagocytosis, Engulfment Intracellularly Calcium-gated Chloride Channel Activity Positive Regulation Of Icosanoid Secretion Ketone Catabolic Process Renal Water Homeostasis Phospholipid Scramblase Activity	Guanyl Nucleotide Binding G-protein Beta/gamma-subunit Complex Binding Heterotrimeric G-protein Complex Adenylate Cyclase Regulator Activity GTPase Activity Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway GTP Binding G Protein Activity G Protein-coupled Receptor Binding Mu-type Opioid Receptor Binding Cytoplasm Negative Regulation Of Transport Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway G Protein-coupled Serotonin Receptor Signaling Pathway G Protein-coupled Serotonin Receptor Binding Cell Body Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway Response To Prostaglandin E Corticotropin-releasing Hormone Receptor 1 Binding Negative Regulation Of Adenylate Cyclase-activating Adrenergic Receptor Signaling Pathway Regulation Of Cellular Component Organization Cytoplasmic Vesicle Regulation Of Cell Communication Centriolar Satellite Regulation Of Protein Localization Regulation Of Signaling Plasma Membrane Regulation Of Transport Negative Regulation Of Cellular Component Organization Adenylate Cyclase-inhibiting Serotonin Receptor Signaling Pathway Negative Regulation Of Adenylate Cyclase Activity Golgi Apparatus Regulation Of Establishment Of Protein Localization G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Endocytosis Negative Regulation Of Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Midbody Identical Protein Binding Regulation Of Macroautophagy Regulation Of Relaxation Of Muscle Negative Regulation Of Receptor Internalization Regulation Of Proteasomal Protein Catabolic Process Extracellular Vesicle Cellular Response To Acidic PH Regulation Of Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Regulation Of MAPK Cascade Cell Projection G Protein-coupled Acetylcholine Receptor Signaling Pathway G Protein-coupled Dopamine Receptor Signaling Pathway Regulation Of Intracellular Signal Transduction
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