Wiki-Pi
Answer Survey
Home
About
Help
Advanced Search
PLN and ATP2A1
Number of citations of the paper that reports this interaction (PMID
10551848
)
21
Data Source:
HPRD
(in vitro, in vivo)
PLN
ATP2A1
Gene Name
phospholamban
ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Mitochondrion
Endoplasmic Reticulum
Membrane
Mitochondrial Membrane
Vesicle
Sarcoplasmic Reticulum Membrane
Perinuclear Region Of Cytoplasm
Calcium Ion-transporting ATPase Complex
Endoplasmic Reticulum Membrane
Endoplasmic Reticulum-Golgi Intermediate Compartment
Membrane
Integral Component Of Membrane
Sarcoplasmic Reticulum
Platelet Dense Tubular Network Membrane
H Zone
I Band
Sarcoplasmic Reticulum Membrane
Calcium Channel Complex
Perinuclear Region Of Cytoplasm
Molecular Function
Enzyme Inhibitor Activity
Calcium Channel Regulator Activity
Protein Binding
ATPase Inhibitor Activity
Identical Protein Binding
ATPase Binding
Calcium-transporting ATPase Activity
Calcium Ion Binding
Protein Binding
ATP Binding
Protein Homodimerization Activity
Biological Process
Regulation Of The Force Of Heart Contraction
Calcium Ion Transport
Blood Circulation
Regulation Of Heart Contraction
Response To Zinc Ion
Negative Regulation Of Heart Rate
Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion
Negative Regulation Of ATPase Activity
Response To Insulin
Response To Testosterone
Negative Regulation Of Catalytic Activity
Cardiac Muscle Tissue Development
Protein Homooligomerization
Cytosolic Calcium Ion Homeostasis
Regulation Of Calcium Ion Transport
Negative Regulation Of Calcium Ion Transport
Relaxation Of Cardiac Muscle
Regulation Of Ryanodine-sensitive Calcium-release Channel Activity
Regulation Of Cardiac Muscle Cell Contraction
Adrenergic Receptor Signaling Pathway Involved In Heart Process
Regulation Of Cardiac Muscle Cell Membrane Potential
Regulation Of The Force Of Heart Contraction By Cardiac Conduction
Negative Regulation Of Calcium Ion Import
Negative Regulation Of Calcium Ion Transmembrane Transporter Activity
Negative Regulation Of Calcium Ion Binding
Regulation Of Calcium-transporting ATPase Activity
Negative Regulation Of Calcium-transporting ATPase Activity
Regulation Of Relaxation Of Cardiac Muscle
Negative Regulation Of Calcium Ion Import Into Sarcoplasmic Reticulum
Calcium Ion Transport
Regulation Of Striated Muscle Contraction
Blood Coagulation
Metabolic Process
Apoptotic Mitochondrial Changes
Positive Regulation Of Fast-twitch Skeletal Muscle Fiber Contraction
Positive Regulation Of Endoplasmic Reticulum Calcium Ion Concentration
Negative Regulation Of Endoplasmic Reticulum Calcium Ion Concentration
Ion Transmembrane Transport
Response To Endoplasmic Reticulum Stress
Negative Regulation Of Striated Muscle Contraction
Positive Regulation Of Mitochondrial Calcium Ion Concentration
Maintenance Of Mitochondrion Location
Transmembrane Transport
Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress
Calcium Ion Import
Calcium Ion Transmembrane Transport
Relaxation Of Skeletal Muscle
Pathways
Ion transport by P-type ATPases
Ion channel transport
Ion transport by P-type ATPases
Ion channel transport
Pre-NOTCH Processing in Golgi
Platelet homeostasis
Reduction of cytosolic Ca++ levels
Signaling by NOTCH
Pre-NOTCH Expression and Processing
Platelet calcium homeostasis
Drugs
Diseases
GWAS
Cardiac structure and function (
19584346
)
QT interval (
23166209
19305408
19305409
19587794
)
Ventricular conduction (
21076409
)
Body mass index (
19079260
)
Weight (
19079260
)
Protein-Protein Interactions
11 interactors:
ATP2A1
ATP2A2
DMPK
DVL3
EDA
LDLRAD1
PPP1R3A
PRKACA
S100A1
SLN
TMEM79
4 interactors:
IRS1
IRS2
PLN
SLN
Entrez ID
5350
487
HPRD ID
01395
00157
Ensembl ID
ENSG00000198523
ENSG00000196296
Uniprot IDs
P26678
Q5R352
B3KY17
O14983
Q7Z675
PDB IDs
1K9N
1KCH
1PLN
1PLP
1PSL
1ZLL
2HYN
Enriched GO Terms of Interacting Partners
?
Positive Regulation Of Endoplasmic Reticulum Calcium Ion Concentration
Regulation Of Heart Contraction
Regulation Of Calcium Ion Transmembrane Transport
Regulation Of Calcium Ion Transmembrane Transporter Activity
Cellular Calcium Ion Homeostasis
Calcium Ion Homeostasis
Regulation Of Striated Muscle Contraction
Sarcoplasmic Reticulum Calcium Ion Transport
Chemical Homeostasis
Cellular Metal Ion Homeostasis
Cellular Cation Homeostasis
Cellular Ion Homeostasis
Regulation Of Ion Transmembrane Transporter Activity
Regulation Of Transmembrane Transporter Activity
Metal Ion Homeostasis
Regulation Of Muscle Contraction
Relaxation Of Muscle
Regulation Of Cardiac Muscle Contraction By Calcium Ion Signaling
Cellular Chemical Homeostasis
Ion Homeostasis
Regulation Of Calcium Ion Transport
Regulation Of Body Fluid Levels
Regulation Of The Force Of Heart Contraction
Calcium Ion Import
Endoplasmic Reticulum Calcium Ion Homeostasis
Homeostatic Process
Cellular Homeostasis
Epidermis Development
Multicellular Organismal Water Homeostasis
Calcium Ion Transport
Water Homeostasis
Nuclear Envelope Organization
Calcium Ion Transport From Cytosol To Endoplasmic Reticulum
Positive Regulation Of Dense Core Granule Biogenesis
Calcium Ion Import Into Sarcoplasmic Reticulum
Positive Regulation Of Fast-twitch Skeletal Muscle Fiber Contraction
Regulation Of Heart Rate
Regulation Of Cardiac Muscle Contraction
Regulation Of Cation Channel Activity
Intracellular Signal Transduction
Programmed Cell Death
Regulation Of Ion Transmembrane Transport
Blood Coagulation
Hemostasis
Cell Death
Death
Calcium-mediated Signaling
Hair Follicle Development
Hair Cycle Process
Epithelium Development
Negative Regulation Of Calcium Ion Binding
Negative Regulation Of Ion Transmembrane Transport
Negative Regulation Of Transmembrane Transport
Regulation Of Calcium-transporting ATPase Activity
Negative Regulation Of Transport
Negative Regulation Of Calcium Ion Import
Negative Regulation Of Ion Transport
Regulation Of Relaxation Of Muscle
Positive Regulation Of Fatty Acid Beta-oxidation
Positive Regulation Of Glycogen Biosynthetic Process
Negative Regulation Of Calcium Ion Transmembrane Transporter Activity
Positive Regulation Of Fatty Acid Oxidation
Regulation Of Fatty Acid Beta-oxidation
JAK-STAT Cascade Involved In Growth Hormone Signaling Pathway
Regulation Of Calcium Ion Import
Growth Hormone Receptor Signaling Pathway
Cellular Response To Growth Hormone Stimulus
Positive Regulation Of Lipid Catabolic Process
Response To Insulin
Positive Regulation Of Fatty Acid Metabolic Process
Regulation Of Glycogen Biosynthetic Process
Regulation Of Fatty Acid Oxidation
Positive Regulation Of Glucose Metabolic Process
Regulation Of Glycogen Metabolic Process
Response To Growth Hormone
Negative Regulation Of Transporter Activity
Regulation Of ATPase Activity
Negative Regulation Of Calcium Ion Transport
Positive Regulation Of Mesenchymal Cell Proliferation
Positive Regulation Of Glucose Import
Regulation Of Ion Transmembrane Transport
Regulation Of Mesenchymal Cell Proliferation
Positive Regulation Of Glucose Transport
Response To Peptide Hormone
JAK-STAT Cascade
Regulation Of Lipid Catabolic Process
Response To Peptide
Regulation Of Calcium Ion Transmembrane Transport
Regulation Of Calcium Ion Transmembrane Transporter Activity
Regulation Of Glucose Import
Positive Regulation Of Stem Cell Proliferation
Regulation Of Generation Of Precursor Metabolites And Energy
Regulation Of Ion Transport
Regulation Of Fatty Acid Metabolic Process
Regulation Of Cellular Component Movement
Regulation Of Glucose Transport
Negative Regulation Of Binding
Regulation Of Catalytic Activity
Regulation Of Glucose Metabolic Process
Regulation Of Stem Cell Proliferation
Tagcloud
?
augment
axillary
ccr7
cd45
clue
conditioned
cues
deadly
drained
emerge
fivefold
infiltrated
infiltrating
intriguingly
leukocyte
leukocytes
lymph
mcf
microenvironment
nln
nlns
nodes
plns
secreted
secretions
skbr3
subsets
tals
tributaries
Tagcloud (Difference)
?
augment
axillary
ccr7
cd45
clue
conditioned
cues
deadly
drained
emerge
fivefold
infiltrated
infiltrating
intriguingly
leukocyte
leukocytes
lymph
mcf
microenvironment
nln
nlns
nodes
plns
secreted
secretions
skbr3
subsets
tals
tributaries
Tagcloud (Intersection)
?