FXYD3 and FBXL12

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		FXYD3	FBXL12
Gene Name		FXYD domain containing ion transport regulator 3	F-box and leucine-rich repeat protein 12
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Membrane Plasma Membrane Integral Component Of Plasma Membrane Chloride Channel Complex Extracellular Vesicular Exosome	Ubiquitin Ligase Complex Cytoplasm
	Molecular Function	Chloride Channel Activity ATPase Binding	Protein Binding
	Biological Process	Chloride Transport Ion Transmembrane Transport Regulation Of Catalytic Activity Transmembrane Transport Chloride Transmembrane Transport	Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination
Pathways		Ion transport by P-type ATPases Ion channel transport
Drugs
Diseases
GWAS
Protein-Protein Interactions		5 interactors: FBXL12 MAPK6 NR4A1 NUDT3 SERBP1	14 interactors: A2M APOE CDC37 CDKN1C DOCK8 ECSIT FXYD3 LNX1 MAST1 PSEN1 PSEN2 RNF32 SMAD1 TGFBR1
Entrez ID		5349	54850
HPRD ID		05410	12363
Ensembl ID		ENSG00000089356	ENSG00000127452
Uniprot IDs		Q14802	Q9NXK8
PDB IDs
Enriched GO Terms of Interacting Partners?		Diphosphoinositol Polyphosphate Catabolic Process Diadenosine Polyphosphate Catabolic Process	Regulation Of Catalytic Activity Embryonic Morphogenesis Intracellular Signal Transduction Regulation Of Protein Kinase Activity Regulation Of Kinase Activity Thymus Development Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Negative Regulation Of Cell Death Generation Of Neurons Amyloid Precursor Protein Catabolic Process Anatomical Structure Morphogenesis Neurogenesis Regulation Of Protein Phosphorylation Cell Fate Commitment Neuron Differentiation Embryo Development Negative Regulation Of Protein Phosphorylation Cell Activation Response To Wounding Regulation Of Cellular Protein Metabolic Process Regulation Of Phosphorylation Beta-amyloid Metabolic Process Amyloid Precursor Protein Metabolic Process Negative Regulation Of Epithelial Cell Proliferation Negative Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Phosphorylation Membrane Protein Ectodomain Proteolysis Notch Receptor Processing Response To Cholesterol Regulation Of Protein Binding Regulation Of Protein Metabolic Process Regulation Of Apoptotic Process Regulation Of Phosphorus Metabolic Process Negative Regulation Of Protein Metabolic Process Regulation Of Epidermal Growth Factor-activated Receptor Activity Nervous System Development Regulation Of Cell Death Regulation Of Synaptic Plasticity Regulation Of Cell Morphogenesis Pattern Specification Process Regulation Of Cell Projection Organization Neuron Development Gland Development Cell Differentiation Endoplasmic Reticulum Calcium Ion Homeostasis Regulation Of Metabolic Process Response To Stress Dorsal/ventral Neural Tube Patterning Negative Regulation Of Endothelial Cell Proliferation
Tagcloud ?		48h acetylated around caco code dex dexamethasone di enhancer glucocorticoid h4 histone histones hormones inactivation induction intestinal intestine k4 lct lox mapk methylated mitogen p44 pd pd98059 scnn1a transcribed
Tagcloud (Difference) ?		48h acetylated around caco code dex dexamethasone di enhancer glucocorticoid h4 histone histones hormones inactivation induction intestinal intestine k4 lct lox mapk methylated mitogen p44 pd pd98059 scnn1a transcribed
Tagcloud (Intersection) ?