FXYD3 and SLC30A2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		FXYD3	SLC30A2
Description		FXYD domain containing ion transport regulator 3	solute carrier family 30 member 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Plasma Membrane Membrane Extracellular Exosome	Cytoplasm Mitochondrion Mitochondrial Inner Membrane Lysosome Lysosomal Membrane Endosome Late Endosome Plasma Membrane Endosome Membrane Membrane Transport Vesicle Membrane Cytoplasmic Vesicle Zymogen Granule Membrane Secretory Vesicle
	Molecular Function	Chloride Channel Activity Protein Binding Sodium Channel Regulator Activity ATPase Binding Ion Channel Regulator Activity	Zinc Ion Transmembrane Transporter Activity Protein Binding Monoatomic Cation Transmembrane Transporter Activity Antiporter Activity Identical Protein Binding Metal Ion Binding Zinc:proton Antiporter Activity
	Biological Process	Monoatomic Ion Transport Potassium Ion Transport Sodium Ion Transport Chloride Transport Regulation Of Monoatomic Ion Transport Chloride Transmembrane Transport Positive Regulation Of Sodium Ion Export Across Plasma Membrane	Monoatomic Ion Transport Monoatomic Cation Transport Zinc Ion Transport Intracellular Zinc Ion Homeostasis Response To Zinc Ion Transmembrane Transport Zinc Ion Import Into Organelle Zinc Ion Transmembrane Transport Zinc Export Across Plasma Membrane Zinc Ion Import Into Secretory Vesicle Zinc Ion Import Into Zymogen Granule Zinc Ion Import Into Lysosome Zinc Ion Import Into Mitochondrion
Pathways		Ion homeostasis Ion transport by P-type ATPases Potential therapeutics for SARS	Zinc efflux and compartmentalization by the SLC30 family
Drugs
Diseases
GWAS
Interacting Genes		64 interacting genes: AGR3 ANK1 AQP6 AQP9 BCL2L13 BEST2 CD79A CNR2 CREB3 CREB3L1 CYB5R3 EBP ERG28 ERGIC3 FAM209A FBXL12 FCGR2A FFAR2 GHITM GPR152 GPR37L1 GPR42 GPRC5D IBSP KASH5 KCNN4 LMNA LTC4S MAPK6 MFSD11 MGST1 MTIF3 NR4A1 NUDT3 PLPP6 SCN3B SERBP1 SGPL1 SLC10A1 SLC10A6 SLC16A12 SLC18A1 SLC1A1 SLC30A2 SLC35A1 SLC35B1 SLC35H1 SLC39A2 SLC61A1 SPNS3 STRIT1 STX3 TIMM23 TIMMDC1 TLCD1 TMBIM6 TMEM179B TMEM50B TMEM52B TMEM80 TMEM86A TMEM97 TSPO2 XKR3	67 interacting genes: ABHD16A ADAM33 AQP2 AQP6 ATP13A1 C5orf46 CCL4 CCL4L2 CD40 CD52 CD79A CD99L2 CPLX4 CREB3 CTSA CYB561D2 EBAG9 EMP3 ERGIC3 EVI2B F11R FAM174A FDPS FFAR2 FXYD3 FXYD6 GALNT15 GJA5 GJB2 GJB5 GLB1 GOLT1A GPR161 GPR42 GPRC5D HGFAC KASH5 KCNN4 LMNA LTA LYVE1 MS4A13 NDUFAF1 NRM OPRM1 PCNX2 PLPPR1 PVR SEC22A SELL SERPING1 SLC10A6 SLC16A2 SLC18A1 SLC38A7 SLC39A2 SLC7A1 SLC7A8 TAS2R5 TM4SF18 TMEM107 TMEM52B TMEM60 TMEM86A TNFRSF12A TRARG1 YIPF2
Entrez ID		5349	7780
HPRD ID		05410	18057
Ensembl ID		ENSG00000089356	ENSG00000158014
Uniprot IDs		A0A1S5UZ23 Q14802 S4R445	Q9BRI3
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Transmembrane Transport Endoplasmic Reticulum Membrane Organic Anion Transport Endoplasmic Reticulum Protein Binding Pyrimidine Nucleotide-sugar Transmembrane Transport Nucleotide-sugar Transmembrane Transport Sterol Biosynthetic Process Monoatomic Ion Transport UDP-glucose Transmembrane Transport Negative Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Monoatomic Cation Transport Plasma Membrane Zinc Ion Transmembrane Transport Zinc Ion Transport Bile Acid:sodium Symporter Activity Inorganic Ion Transmembrane Transport Organic Hydroxy Compound Transport Steroid Biosynthetic Process Cholesterol Biosynthetic Process Metal Ion Transport Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Monoatomic Anion Channel Activity Monoatomic Ion Transmembrane Transport Channel Activity Inorganic Cation Transmembrane Transport Nuclear Membrane Monoatomic Cation Transmembrane Transport Antiporter Activity Amine Transport Negative Regulation Of Response To Endoplasmic Reticulum Stress	Membrane Transmembrane Transport Plasma Membrane Connexin Complex Gap Junction Channel Activity Gap Junction Renal Water Transport Gap Junction Assembly Positive Regulation Of Sodium Ion Export Across Plasma Membrane Ion Channel Regulator Activity CCR1 Chemokine Receptor Binding Amino Acid Import Across Plasma Membrane Amino Acid Transmembrane Transporter Activity Amino Acid Transmembrane Transport Thyroid Hormone Transmembrane Transporter Activity Metal Ion Transport Protein Binding Positive Regulation Of Immune System Process Monoatomic Cation Transport Aromatic Amino Acid Transport
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