PI4KA and MRPL44

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		PI4KA	MRPL44
Gene Name		phosphatidylinositol 4-kinase, catalytic, alpha	mitochondrial ribosomal protein L44
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Plasma Membrane Focal Adhesion Membrane Golgi-associated Vesicle Membrane Extracellular Vesicular Exosome	Cellular_component Mitochondrial Inner Membrane Ribosome
	Molecular Function	1-phosphatidylinositol 4-kinase Activity Protein Binding ATP Binding	Ribonuclease III Activity Poly(A) RNA Binding
	Biological Process	Phospholipid Metabolic Process Phosphatidylinositol Biosynthetic Process Signal Transduction Small Molecule Metabolic Process Phosphatidylinositol Phosphorylation Phosphatidylinositol-mediated Signaling	RNA Processing Organelle Organization Mitochondrial Translation Mitochondrial Translational Initiation Mitochondrial Translational Elongation Mitochondrial Translational Termination RNA Phosphodiester Bond Hydrolysis, Endonucleolytic
Pathways		Synthesis of PIPs at the Golgi membrane Metabolism of lipids and lipoproteins Synthesis of PIPs at the ER membrane Phospholipid metabolism PI Metabolism	Mitochondrial translation Organelle biogenesis and maintenance Mitochondrial translation elongation Mitochondrial translation initiation Mitochondrial translation termination
Drugs
Diseases
GWAS
Protein-Protein Interactions		9 interactors: C8orf33 CD4 CD7 LCK MRPL44 MTNR1B PITPNA STRN4 TNNT1	15 interactors: ABI2 CEP70 DGKE IMMT ITFG1 NGEF PI4KA PPAP2C PTN SEMA5B SETDB1 SHC1 USP22 VIM ZNF235
Entrez ID		5297	65080
HPRD ID		08972	14763
Ensembl ID		ENSG00000241973	ENSG00000135900
Uniprot IDs		B4DYG5 J3KN10 P42356 Q4LE69	Q9H9J2
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Defense Response To Virus By Virus T Cell Aggregation T Cell Activation Lymphocyte Aggregation Leukocyte Aggregation Leukocyte Cell-cell Adhesion Homotypic Cell-cell Adhesion Lymphocyte Activation T Cell Costimulation Regulation Of Defense Response To Virus Induction By Virus Of Host Cell-cell Fusion Protein Palmitoleylation Leukocyte Activation Single Organismal Cell-cell Adhesion T Cell Receptor Signaling Pathway Antigen Receptor-mediated Signaling Pathway Regulation Of Muscle Contraction Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Positive Regulation Of Peptidyl-tyrosine Phosphorylation T Cell Differentiation Cell Activation Positive Regulation Of T Cell Activation Regulation Of Peptidyl-tyrosine Phosphorylation Positive Regulation Of Homotypic Cell-cell Adhesion Slow-twitch Skeletal Muscle Fiber Contraction Enzyme Linked Receptor Protein Signaling Pathway Lymphocyte Differentiation Positive Regulation Of Gamma-delta T Cell Differentiation Positive Regulation Of Cell-cell Adhesion Positive Regulation Of Gamma-delta T Cell Activation Positive Regulation Of Uterine Smooth Muscle Contraction Immune Response-activating Cell Surface Receptor Signaling Pathway Regulation Of T Cell Activation Positive Regulation Of Cell Activation Regulation Of Gamma-delta T Cell Differentiation Modulation By Virus Of Host Process Cellular Zinc Ion Homeostasis Positive Regulation Of Interleukin-2 Biosynthetic Process Leukocyte Differentiation Zinc Ion Homeostasis Cell Adhesion Positive Regulation Of Tyrosine Phosphorylation Of Stat5 Protein Positive Regulation Of T Cell Receptor Signaling Pathway Regulation Of Cell-cell Adhesion Positive Regulation Of Cell Adhesion Immune Response-regulating Cell Surface Receptor Signaling Pathway Locomotion Regulation Of Lymphocyte Activation Regulation Of Cellular Amino Acid Metabolic Process Immune Response
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