PI4KA and STRN4

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		PI4KA	STRN4
Description		phosphatidylinositol 4-kinase alpha	striatin 4
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Plasma Membrane Focal Adhesion Membrane Golgi-associated Vesicle Membrane Extracellular Exosome	Cytoplasm Dendrite Protein-containing Complex Neuronal Cell Body Dendritic Spine FAR/SIN/STRIPAK Complex Postsynapse Glutamatergic Synapse GABA-ergic Synapse
	Molecular Function	Nucleotide Binding 1-phosphatidylinositol 4-kinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity Cadherin Binding	Protein Binding Calmodulin Binding Protein Domain Specific Binding Protein-macromolecule Adaptor Activity Protein-containing Complex Binding Protein Phosphatase 2A Binding Armadillo Repeat Domain Binding
	Biological Process	Lipid Metabolic Process Phosphatidylinositol Biosynthetic Process Signal Transduction Host-mediated Perturbation Of Viral Process Phosphatidylinositol Phosphate Biosynthetic Process Phosphatidylinositol-mediated Signaling Reorganization Of Cellular Membranes To Establish Viral Sites Of Replication	Negative Regulation Of Hippo Signaling Regulation Of Modification Of Postsynaptic Structure
Pathways		Synthesis of PIPs at the ER membrane Synthesis of PIPs at the Golgi membrane
Drugs
Diseases
GWAS		Fulminant type 1 diabetes ( 30552108) Metabolite levels ( 23823483) Monocyte percentage of white cells ( 32888494)	Aspartate aminotransferase levels ( 33547301) Chronic lymphocytic leukemia ( 18758461 28165464) Primary sclerosing cholangitis ( 23603763)
Interacting Genes		10 interacting genes: C8orf33 CD4 CD7 LCK MRPL44 MTNR1B PITPNA SNX9 STRN4 TNNT1	28 interacting genes: AK5 ASNS CALM1 CAV1 CLDN12 CRK DDX39B DFFA ECSIT GDF9 JUN KLHDC2 MAP4K1 MAP4K2 MAP4K3 MAP4K4 MIF MSANTD2 MTG1 NBEA PBDC1 PI4KA PLPPR3 PPBP SLC25A6 TNIK WIPI2 WNT7A
Entrez ID		5297	29888
HPRD ID		08972	18125
Ensembl ID		ENSG00000241973	ENSG00000090372
Uniprot IDs		A0A140VK35 B4DYG5 P42356	F5GYK2 Q59GV6 Q9NRL3
PDB IDs		6BQ1 9B9G 9BAX
Enriched GO Terms of Interacting Partners?			MAP Kinase Kinase Kinase Kinase Activity MAPK Cascade Regulation Of MAPK Cascade JNK Cascade Regulation Of JNK Cascade Intracellular Signaling Cassette Positive Regulation Of MAPK Cascade Positive Regulation Of JNK Cascade Negative Regulation Of Apoptotic Process Positive Regulation Of Intracellular Signal Transduction Kinase Activity Intracellular Signal Transduction Negative Regulation Of Programmed Cell Death Positive Regulation Of Signal Transduction Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Cellular Response To Transforming Growth Factor Beta Stimulus Nucleotide Binding ATP Binding Response To Transforming Growth Factor Beta Protein Serine Kinase Activity Protein Phosphorylation Signal Transduction Regulation Of Cell Communication By Electrical Coupling Positive Regulation Of Cell Communication Positive Regulation Of Signaling Phosphorylation Cytokine Activity Regulation Of Fibroblast Proliferation Protein Serine/threonine Kinase Activity Positive Regulation Of Cell Junction Assembly Regulation Of Intracellular Signal Transduction Regulation Of Cardiac Muscle Cell Action Potential
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