PI4KA and STRN4

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		PI4KA	STRN4
Gene Name		phosphatidylinositol 4-kinase, catalytic, alpha	striatin, calmodulin binding protein 4
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Plasma Membrane Focal Adhesion Membrane Golgi-associated Vesicle Membrane Extracellular Vesicular Exosome	Protein Phosphatase Type 2A Complex Cytoplasm Membrane Dendritic Spine
	Molecular Function	1-phosphatidylinositol 4-kinase Activity Protein Binding ATP Binding	Protein Binding Calmodulin Binding Protein Complex Binding Protein Phosphatase 2A Binding Armadillo Repeat Domain Binding
	Biological Process	Phospholipid Metabolic Process Phosphatidylinositol Biosynthetic Process Signal Transduction Small Molecule Metabolic Process Phosphatidylinositol Phosphorylation Phosphatidylinositol-mediated Signaling	Biological_process
Pathways		Synthesis of PIPs at the Golgi membrane Metabolism of lipids and lipoproteins Synthesis of PIPs at the ER membrane Phospholipid metabolism PI Metabolism
Drugs
Diseases
GWAS			Chronic lymphocytic leukemia ( 18758461)
Protein-Protein Interactions		9 interactors: C8orf33 CD4 CD7 LCK MRPL44 MTNR1B PITPNA STRN4 TNNT1	22 interactors: AK5 ASNS CALM1 CAV1 CLDN12 DDX39B DFFA ECSIT GDF9 JUN KLHDC2 LPPR3 MIF MSANTD2 MTG1 NBEA PBDC1 PI4KA PPBP SLC25A6 WIPI2 WNT7A
Entrez ID		5297	29888
HPRD ID		08972	18125
Ensembl ID		ENSG00000241973	ENSG00000090372
Uniprot IDs		B4DYG5 J3KN10 P42356 Q4LE69	F5GYK2 F8VYA6 Q59GV6 Q9NRL3
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Defense Response To Virus By Virus T Cell Aggregation T Cell Activation Lymphocyte Aggregation Leukocyte Aggregation Leukocyte Cell-cell Adhesion Homotypic Cell-cell Adhesion Lymphocyte Activation T Cell Costimulation Regulation Of Defense Response To Virus Induction By Virus Of Host Cell-cell Fusion Protein Palmitoleylation Leukocyte Activation Single Organismal Cell-cell Adhesion T Cell Receptor Signaling Pathway Antigen Receptor-mediated Signaling Pathway Regulation Of Muscle Contraction Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Positive Regulation Of Peptidyl-tyrosine Phosphorylation T Cell Differentiation Cell Activation Positive Regulation Of T Cell Activation Regulation Of Peptidyl-tyrosine Phosphorylation Positive Regulation Of Homotypic Cell-cell Adhesion Slow-twitch Skeletal Muscle Fiber Contraction Enzyme Linked Receptor Protein Signaling Pathway Lymphocyte Differentiation Positive Regulation Of Gamma-delta T Cell Differentiation Positive Regulation Of Cell-cell Adhesion Positive Regulation Of Gamma-delta T Cell Activation Positive Regulation Of Uterine Smooth Muscle Contraction Immune Response-activating Cell Surface Receptor Signaling Pathway Regulation Of T Cell Activation Positive Regulation Of Cell Activation Regulation Of Gamma-delta T Cell Differentiation Modulation By Virus Of Host Process Cellular Zinc Ion Homeostasis Positive Regulation Of Interleukin-2 Biosynthetic Process Leukocyte Differentiation Zinc Ion Homeostasis Cell Adhesion Positive Regulation Of Tyrosine Phosphorylation Of Stat5 Protein Positive Regulation Of T Cell Receptor Signaling Pathway Regulation Of Cell-cell Adhesion Positive Regulation Of Cell Adhesion Immune Response-regulating Cell Surface Receptor Signaling Pathway Locomotion Regulation Of Lymphocyte Activation Regulation Of Cellular Amino Acid Metabolic Process Immune Response	Regulation Of Protein Autophosphorylation Cellular Response To Starvation Cellular Response To Nutrient Levels Response To Starvation Cellular Response To Extracellular Stimulus Regulation Of Oxidoreductase Activity Negative Regulation Of Protein Autophosphorylation Positive Regulation Of Phosphorylation Regulation Of Phosphorylation Response To External Stimulus Response To Organic Cyclic Compound Cellular Localization Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Negative Regulation Of Cell Death Regulation Of Apoptotic Process Response To Calcium Ion Regulation Of Phosphorus Metabolic Process Regulation Of Cell Death Regulation Of Protein Phosphorylation Response To Wounding Positive Regulation Of Protein Phosphorylation Nitric Oxide Metabolic Process Mitochondrion Organization Reactive Nitrogen Species Metabolic Process Response To Nutrient Levels Regulation Of Nitric-oxide Synthase Activity Cellular Response To Transforming Growth Factor Beta Stimulus Regulation Of Immune System Process Response To Extracellular Stimulus Response To Lipid Response To Transforming Growth Factor Beta Response To Organic Substance Positive Regulation Of Ion Transport Cell Communication Positive Regulation Of Cellular Metabolic Process Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Protein Modification Process Negative Regulation Of Ion Transmembrane Transport Regulation Of Cell Cycle Establishment Of Localization In Cell Regulation Of Membrane Repolarization During Action Potential Positive Regulation Of Prostaglandin Secretion Involved In Immune Response DADP Biosynthetic Process Negative Regulation Of Peptidyl-tyrosine Autophosphorylation Wnt Signaling Pathway Involved In Wound Healing, Spreading Of Epidermal Cells Negative Regulation Of Apoptotic DNA Fragmentation Cellular Response To Potassium Ion Starvation L-asparagine Biosynthetic Process
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