PI4KA and CD7

Number of citations of the paper that reports this interaction (PubMedID 12594831)
0

Data Source:
HPRD (in vivo)

		PI4KA	CD7
Description		phosphatidylinositol 4-kinase alpha	CD7 molecule
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Plasma Membrane Focal Adhesion Membrane Golgi-associated Vesicle Membrane Extracellular Exosome	Plasma Membrane Membrane
	Molecular Function	Nucleotide Binding 1-phosphatidylinositol 4-kinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity Cadherin Binding	Transmembrane Signaling Receptor Activity Protein Binding Signaling Receptor Activity
	Biological Process	Lipid Metabolic Process Phosphatidylinositol Biosynthetic Process Signal Transduction Host-mediated Perturbation Of Viral Process Phosphatidylinositol Phosphate Biosynthetic Process Phosphatidylinositol-mediated Signaling Reorganization Of Cellular Membranes To Establish Viral Sites Of Replication	Adaptive Immune Response Immune System Process Positive Regulation Of T Cell Cytokine Production Immune Response Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Interleukin-2-mediated Signaling Pathway T Cell Activation
Pathways		Synthesis of PIPs at the ER membrane Synthesis of PIPs at the Golgi membrane
Drugs
Diseases
GWAS		Fulminant type 1 diabetes ( 30552108) Metabolite levels ( 23823483) Monocyte percentage of white cells ( 32888494)	Blood protein levels ( 30072576)
Interacting Genes		10 interacting genes: C8orf33 CD4 CD7 LCK MRPL44 MTNR1B PITPNA SNX9 STRN4 TNNT1	9 interacting genes: CPTP CTSL LGALS1 NFKBIA PI4KA PIK3R1 SEC22A SECTM1 SNAP29
Entrez ID		5297	924
HPRD ID		08972	01732
Ensembl ID		ENSG00000241973	ENSG00000173762
Uniprot IDs		A0A140VK35 B4DYG5 P42356	P09564 Q29VG3
PDB IDs		6BQ1 9B9G 9BAX
Enriched GO Terms of Interacting Partners?			Membrane Organization Serpin Family Protein Binding Fusion Of Virus Membrane With Host Endosome Membrane Plasma Membrane Membrane Fusion Lactose Binding Regulation Of Canonical NF-kappaB Signal Transduction Regulation Of Cytokine Production Regulation Of Protein Import Into Nucleus Phosphatidylinositol Phosphate Biosynthetic Process Reorganization Of Cellular Membranes To Establish Viral Sites Of Replication SNAP Receptor Activity Macrophage Apoptotic Process Elastin Catabolic Process Fusion Of Virus Membrane With Host Plasma Membrane Immune System Process Chromaffin Granule Enkephalin Processing B Cell Differentiation Regulation Of Immune Response Positive Regulation Of Immune System Process Galectin Complex Receptor Ligand Activity Negative Regulation Of Hemopoiesis Lymphocyte Activation Involved In Immune Response Regulation Of Hemopoiesis Negative Regulation Of Multicellular Organismal Process Cytokine-mediated Signaling Pathway Regulation Of Nucleocytoplasmic Transport Import Into Nucleus Protein Transport Protein Import Into Nucleus I-kappaB/NF-kappaB Complex Negative Regulation Of Myeloid Cell Differentiation Kinase Regulator Activity Perinuclear Endoplasmic Reticulum Membrane Phosphatidylinositol Biosynthetic Process Phosphatidylinositol Metabolic Process 1-phosphatidylinositol 4-kinase Activity Ciliary Pocket Membrane Elastin Metabolic Process Endolysosome Lumen Inflammatory Cell Apoptotic Process Leukocyte Activation Involved In Immune Response Positive Regulation Of Dendritic Cell Differentiation Cell Activation Involved In Immune Response Plasma Cell Differentiation Regulation Of Intracellular Protein Transport Nucleotide-binding Oligomerization Domain Containing 1 Signaling Pathway Establishment Of Protein Localization
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