LSM7 and ZSCAN26

Number of citations of the paper that reports this interaction (PubMedID 21988832)
38

Data Source:
BioGRID (two hybrid)

		LSM7	ZSCAN26
Description		LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated	zinc finger and SCAN domain containing 26
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex U6 SnRNP U12-type Spliceosomal Complex Cytosol U4/U6 X U5 Tri-snRNP Complex U2-type Prespliceosome U2-type Precatalytic Spliceosome Catalytic Step 2 Spliceosome Spliceosomal Tri-snRNP Complex Lsm2-8 Complex Lsm1-7-Pat1 Complex Ribonucleoprotein Complex	Nucleus Nucleoplasm Cytosol
	Molecular Function	RNA Binding Protein Binding U6 SnRNA Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	MRNA Splicing, Via Spliceosome Nuclear-transcribed MRNA Catabolic Process MRNA Processing RNA Splicing	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II
Pathways		mRNA decay by 5' to 3' exoribonuclease mRNA decay by 5' to 3' exoribonuclease mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Parkinson's disease ( 28892059)	Asthma and major depressive disorder ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Refractive error ( 32231278)
Interacting Genes		24 interacting genes: CEBPA DDIT4L EPHA2 EXOSC6 EXOSC8 LDB1 LSM1 LSM2 LSM3 LSM5 LSM6 LSM8 MYH13 NPY1R PFKM RAB29 RASSF5 SMN1 SNRPD3 SNRPF SYT17 TACC1 TCL1B ZSCAN26	16 interacting genes: CCDC136 CCNDBP1 CDR2L FSD2 GOLGA6L9 KRTAP10-1 KRTAP10-3 KRTAP10-4 KRTAP10-5 KRTAP10-7 KRTAP10-9 KRTAP4-12 LSM7 MTUS2 PDE4DIP TRIM41
Entrez ID		51690	7741
HPRD ID		06287	15746
Ensembl ID		ENSG00000130332	ENSG00000197062
Uniprot IDs		Q9UK45	A0A024RCN4 A0A087X2F1 B3KTR1 B4DMT1 B4DVH3 Q16670
PDB IDs		3JCR 5O9Z 6AH0 6AHD 6QW6 6QX9 7ABG 8H6E 8H6J 8H6K 8H6L 8QO9 8QXD 8QZS 8R08 8R09 8R0A 8R0B 8RM5
Enriched GO Terms of Interacting Partners?		U4/U6 X U5 Tri-snRNP Complex Lsm2-8 Complex U2-type Precatalytic Spliceosome U6 SnRNP RNA Splicing, Via Transesterification Reactions Lsm1-7-Pat1 Complex MRNA Metabolic Process RNA Splicing MRNA Processing Spliceosomal Complex RNA Processing MRNA Splicing, Via Spliceosome RNA Metabolic Process Precatalytic Spliceosome MRNA Catabolic Process Ribonucleoprotein Complex Nucleobase-containing Compound Metabolic Process RNA Catabolic Process Spliceosomal SnRNP Assembly Nucleobase-containing Compound Catabolic Process Nucleic Acid Metabolic Process Small Nuclear Ribonucleoprotein Complex SMN-Sm Protein Complex RNA Binding Catalytic Step 2 Spliceosome P-body PICln-Sm Protein Complex Spliceosomal Complex Assembly U7 SnRNP 7-methylguanosine Cap Hypermethylation U4 SnRNA 3'-end Processing Nucleolar Exosome (RNase Complex) U4 SnRNP Nuclear MRNA Surveillance Methylosome U6 SnRNA Binding Protein-RNA Complex Assembly Cytoplasmic Exosome (RNase Complex) RNA Exonuclease Activity RRNA Catabolic Process Nuclear Exosome (RNase Complex) Exosome (RNase Complex) U1 SnRNP Nucleoplasm U5 SnRNP SnRNA 3'-end Processing Nuclear-transcribed MRNA Catabolic Process Macromolecule Catabolic Process U2-type Prespliceosome Assembly U12-type Spliceosomal Complex	Keratin Filament Intermediate Filament
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