GET3 and STATH

Number of citations: 54 (PubMedID 22505607)
Data Source: BioGRID (pull down)

		GET3	STATH
Name		guided entry of tail-anchored proteins factor 3, ATPase	statherin
Structure			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane GET Complex Extracellular Exosome	Extracellular Region
	Molecular Function	Nucleotide Binding Protein Binding ATP Binding Hydrolase Activity ATP Hydrolysis Activity Membrane Insertase Activity Metal Ion Binding	Protein Binding Extracellular Matrix Constituent, Lubricant Activity Structural Constituent Of Tooth Enamel Hydroxyapatite Binding
	Biological Process	Antigen Processing And Presentation Of Endogenous Peptide Antigen Via MHC Class I Protein Insertion Into ER Membrane Tail-anchored Membrane Protein Insertion Into ER Membrane	Ossification Regulation Of Bone Mineralization Negative Regulation Of Bone Mineralization Biomineral Tissue Development Defense Response To Bacterium Saliva Secretion
Pathways		Insertion of tail-anchored proteins into the endoplasmic reticulum membrane	None
Drugs		ATP	None
GWAS		No GWAS studies recorded	No GWAS studies recorded
Interacting Genes		38 interacting genes: AGR2 APLN ASPH CACNA1A CREB3L4 EMSY FAM209A FKBP7 GOLM1 GPX7 GPX8 HILPDA IGFBP6 KCNE4 KCNE5 LDLRAD4 PDIA6 PEX14 PFDN1 PGRMC1 PGRMC2 PRB3 PRR4 RHEX SEC61A1 SEC61B SMIM19 SPP1 STATH SYPL2 TK1 TMEM154 TMEM51 TMX1 TTR VAMP2 VWC2 WFDC3	30 interacting genes: AQP6 C16orf92 DERL3 ERGIC3 FAM209A FAM210B FCRL3 FKBP7 GET3 GPR152 GPR42 KCNJ6 LEUTX MRM1 MTIF3 OPRPN OVGP1 REEP4 SAR1A SGPL1 SLC10A1 SLC10A6 SLC35H1 SLC39A2 SLC61A1 SPNS3 TFAM TLCD4 TMEM80 TMX2
Entrez ID		439	6779
HPRD ID		03555	01696
Ensembl ID		ENSG00000198356	ENSG00000126549
Uniprot IDs		O43681	P02808
PDB IDs		6SO5 8CQZ 8CR1 8CR2	Not available
GO Terms Enriched among Interactors		Extracellular Region Endoplasmic Reticulum Lumen Intracellular Protein Transmembrane Transport Body Fluid Secretion Sec61 Translocon Complex SRP-dependent Cotranslational Protein Targeting To Membrane, Translocation Post-translational Protein Targeting To Membrane, Translocation Endoplasmic Reticulum Extracellular Space Regulation Of Body Fluid Levels Membrane Repolarization During Ventricular Cardiac Muscle Cell Action Potential Voltage-gated Potassium Channel Activity Involved In Ventricular Cardiac Muscle Cell Action Potential Repolarization Ventricular Cardiac Muscle Cell Membrane Repolarization Mucus Secretion Potassium Ion Export Across Plasma Membrane Protein Transmembrane Transport Ventricular Cardiac Muscle Cell Action Potential Voltage-gated Potassium Channel Complex Regulation Of Heart Contraction Amyloid-beta Binding Glutathione Peroxidase Activity Protein Disulfide Isomerase Activity Membrane Repolarization During Cardiac Muscle Cell Action Potential Delayed Rectifier Potassium Channel Activity Membrane Repolarization During Action Potential Regulation Of Ventricular Cardiac Muscle Cell Membrane Repolarization Protein Binding Regulation Of System Process Protein-disulfide Reductase Activity	Bile Acid:sodium Symporter Activity