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PHAX and RPS6KA1
Number of citations of the paper that reports this interaction (PMID
21900206
)
27
Data Source:
BioGRID
(two hybrid)
PHAX
RPS6KA1
Gene Name
phosphorylated adaptor for RNA export
ribosomal protein S6 kinase, 90kDa, polypeptide 1
Image
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
Nucleolus
Cytosol
Cajal Body
Neuronal Cell Body
Intracellular Membrane-bounded Organelle
Nucleus
Nucleoplasm
Cytoplasm
Spindle
Cytosol
Molecular Function
RNA Binding
Toxic Substance Binding
Magnesium Ion Binding
Protein Serine/threonine Kinase Activity
Protein Serine/threonine/tyrosine Kinase Activity
Protein Binding
ATP Binding
Cysteine-type Endopeptidase Inhibitor Activity Involved In Apoptotic Process
Biological Process
Spliceosomal SnRNP Assembly
SnRNA Export From Nucleus
Gene Expression
Protein Transport
NcRNA Metabolic Process
Toll-like Receptor Signaling Pathway
MyD88-dependent Toll-like Receptor Signaling Pathway
MyD88-independent Toll-like Receptor Signaling Pathway
Protein Phosphorylation
Cell Cycle
Signal Transduction
Synaptic Transmission
Axon Guidance
Positive Regulation Of Cell Growth
Toll-like Receptor 2 Signaling Pathway
Toll-like Receptor 3 Signaling Pathway
Toll-like Receptor 4 Signaling Pathway
Toll-like Receptor 5 Signaling Pathway
Toll-like Receptor 9 Signaling Pathway
Toll-like Receptor 10 Signaling Pathway
TRIF-dependent Toll-like Receptor Signaling Pathway
Toll-like Receptor TLR1:TLR2 Signaling Pathway
Toll-like Receptor TLR6:TLR2 Signaling Pathway
Negative Regulation Of Apoptotic Process
Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Regulation Of Translation In Response To Stress
Regulation Of DNA-templated Transcription In Response To Stress
Innate Immune Response
Positive Regulation Of Cell Differentiation
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Neurotrophin TRK Receptor Signaling Pathway
Stress-activated MAPK Cascade
Positive Regulation Of Hepatic Stellate Cell Activation
Pathways
snRNP Assembly
Metabolism of non-coding RNA
Signaling by GPCR
CREB phosphorylation
Axon guidance
Toll Like Receptor 7/8 (TLR7/8) Cascade
Cellular Senescence
CREB phosphorylation
L1CAM interactions
Recycling pathway of L1
CREB phosphorylation through the activation of Ras
Toll Like Receptor TLR6:TLR2 Cascade
Toll Like Receptor TLR1:TLR2 Cascade
Activated TLR4 signalling
MyD88 cascade initiated on plasma membrane
Toll Like Receptor 5 (TLR5) Cascade
Gastrin-CREB signalling pathway via PKC and MAPK
RSK activation
Activation of NMDA receptor upon glutamate binding and postsynaptic events
MyD88 dependent cascade initiated on endosome
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation
MyD88:Mal cascade initiated on plasma membrane
Toll Like Receptor 9 (TLR9) Cascade
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
ERK/MAPK targets
Post NMDA receptor activation events
Innate Immune System
Signalling by NGF
MAP kinase activation in TLR cascade
TRIF-mediated TLR3/TLR4 signaling
Senescence-Associated Secretory Phenotype (SASP)
NGF signalling via TRKA from the plasma membrane
MyD88-independent cascade
Toll Like Receptor 2 (TLR2) Cascade
Toll-Like Receptors Cascades
Toll Like Receptor 10 (TLR10) Cascade
Toll Like Receptor 4 (TLR4) Cascade
ERK/MAPK targets
Toll Like Receptor 3 (TLR3) Cascade
MAPK targets/ Nuclear events mediated by MAP kinases
Transmission across Chemical Synapses
Nuclear Events (kinase and transcription factor activation)
Drugs
Diseases
GWAS
Protein-Protein Interactions
14 interactors:
ASPSCR1
GADD45G
GRB7
MKNK1
NSFL1C
PDPK1
RAD23A
RPS6KA1
STK3
TNFSF11
UBXN2A
VAV1
XPO1
ZWINT
51 interactors:
ATXN3
BAD
CARHSP1
CCT4
CDKN1B
CEBPB
CFL1
CREB1
CREBBP
DDAH2
DLC1
EEF1D
EEF2K
ESR1
ETV1
FGFR1
FOS
GBP2
GMFB
GRB2
GSK3B
L1CAM
MAGI1
MAPK1
MAPK3
MAPT
METTL1
MITF
MPP1
MTOR
MXD1
NFKBIA
NR4A1
NR4A2
NR4A3
PDCD4
PDPK1
PHAX
POLDIP3
PPM1G
PPP1R3A
RPTOR
SRF
SRSF5
SYK
TOB2
TSC2
TTK
VCP
YBX1
YWHAB
Entrez ID
51808
6195
HPRD ID
15122
03402
Ensembl ID
ENSG00000164902
ENSG00000117676
Uniprot IDs
Q9H814
E9PRI4
Q15418
PDB IDs
2XC7
2WNT
2Z7Q
2Z7R
2Z7S
3RNY
3TEI
4H3P
Enriched GO Terms of Interacting Partners
?
Regulation Of Protein Metabolic Process
Response To Stress
Regulation Of Cellular Protein Metabolic Process
Enzyme Linked Receptor Protein Signaling Pathway
Apoptotic Process
Programmed Cell Death
Cellular Response To Growth Factor Stimulus
Cell Death
Death
Response To Growth Factor
Regulation Of Catalytic Activity
Nuclear Envelope Reassembly
Positive Regulation Of Cell Activation
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Apoptotic Signaling Pathway
Regulation Of Metabolic Process
Positive Regulation Of JNK Cascade
Positive Regulation Of Stress-activated MAPK Cascade
Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade
Epidermal Growth Factor Receptor Signaling Pathway
Posttranscriptional Regulation Of Gene Expression
Cellular Response To Stimulus
Fibroblast Growth Factor Receptor Signaling Pathway
ERBB Signaling Pathway
Regulation Of JNK Cascade
Response To Stimulus
Positive Regulation Of Protein Kinase Activity
Regulation Of Cell Activation
Cellular Response To Stress
Positive Regulation Of Kinase Activity
Regulation Of Stress-activated MAPK Cascade
Cellular Response To Fibroblast Growth Factor Stimulus
Response To Fibroblast Growth Factor
Positive Regulation Of T Cell Activation
Neurotrophin TRK Receptor Signaling Pathway
Cell Communication
Positive Regulation Of Transferase Activity
Positive Regulation Of Homotypic Cell-cell Adhesion
Neurotrophin Signaling Pathway
Leukocyte Migration
Autophagic Vacuole Assembly
Positive Regulation Of Cell-cell Adhesion
Intracellular Signal Transduction
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Cellular Response To Organic Substance
Proteasomal Protein Catabolic Process
Regulation Of Signal Transduction
Regulation Of Gene Expression
Regulation Of Translation
Activation Of Protein Kinase Activity
Fc Receptor Signaling Pathway
Fc-epsilon Receptor Signaling Pathway
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Positive Regulation Of Cellular Metabolic Process
Fibroblast Growth Factor Receptor Signaling Pathway
Neurotrophin TRK Receptor Signaling Pathway
Epidermal Growth Factor Receptor Signaling Pathway
ERBB Signaling Pathway
Neurotrophin Signaling Pathway
Immune Response-regulating Signaling Pathway
Cellular Response To Fibroblast Growth Factor Stimulus
Innate Immune Response
Response To Fibroblast Growth Factor
Response To Organonitrogen Compound
Cellular Response To Organic Substance
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Positive Regulation Of Metabolic Process
Response To Organic Substance
Enzyme Linked Receptor Protein Signaling Pathway
Response To Hormone
Cellular Response To Growth Factor Stimulus
Regulation Of Immune System Process
Immune Response
Response To Growth Factor
Regulation Of Immune Response
Defense Response
Positive Regulation Of Cellular Biosynthetic Process
Response To Abiotic Stimulus
Phosphatidylinositol-mediated Signaling
Response To External Stimulus
Cellular Response To Hormone Stimulus
Regulation Of Metabolic Process
Positive Regulation Of Macromolecule Biosynthetic Process
Insulin Receptor Signaling Pathway
Response To Peptide
Cellular Response To Heat
Immune System Process
Cell Communication
Regulation Of Phosphorylation
Response To Temperature Stimulus
Response To Peptide Hormone
Positive Regulation Of Transcription, DNA-templated
Signal Transduction
Signaling
Positive Regulation Of Gene Expression
Response To Stress
Regulation Of Cellular Protein Metabolic Process
Regulation Of Protein Metabolic Process
Chemotaxis
Cellular Response To Insulin Stimulus
Tagcloud
?
alkenes
azotic
constructions
gnai1
gnao1
heterocycle
hm
hms
htr1b
htr2a
htr2b
htr4
htr6
htr7
kpnb1
pharmacopeia
prkaca
prkca
prkcb
prkcd
prkce
prkcg
prkd1
propertied
pubchem
rock2
tlr8
tradition
Tagcloud (Difference)
?
alkenes
azotic
constructions
gnai1
gnao1
heterocycle
hm
hms
htr1b
htr2a
htr2b
htr4
htr6
htr7
kpnb1
pharmacopeia
prkaca
prkca
prkcb
prkcd
prkce
prkcg
prkd1
propertied
pubchem
rock2
tlr8
tradition
Tagcloud (Intersection)
?