PHAX and UBXN2A

Number of citations of the paper that reports this interaction (PubMedID 21900206)
0

Data Source:
BioGRID (two hybrid)

		PHAX	UBXN2A
Description		phosphorylated adaptor for RNA export	UBX domain protein 2A
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Cajal Body Neuronal Cell Body Ribonucleoprotein Complex	Nucleus Cytoplasm Endoplasmic Reticulum Golgi Apparatus Cis-Golgi Network Cytosol Dendrite Cell Projection Perikaryon
	Molecular Function	RNA Binding Protein Binding Toxic Substance Binding MRNA Cap Binding Complex Binding	Protein Binding Acetylcholine Receptor Binding Ubiquitin Binding
	Biological Process	SnRNA Export From Nucleus Protein Transport RNA Stabilization	Autophagosome Assembly Golgi Organization Regulation Of Protein Ubiquitination Nuclear Membrane Reassembly Regulation Of Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Protein Catabolic Process Negative Regulation Of Proteolysis Regulation Of Macromolecule Metabolic Process Membrane Fusion Negative Regulation Of ERAD Pathway Cellular Response To Leukemia Inhibitory Factor
Pathways		snRNP Assembly RNA polymerase II transcribes snRNA genes
Drugs
Diseases
GWAS		Bipolar disorder ( 34099189) Colorectal cancer ( 30529582)	Chronotype ( 30696823) Diabetic retinopathy (all NPDR and PDR) ( 30487263) Hemoglobin levels ( 32327693) High light scatter reticulocyte count ( 27863252) High light scatter reticulocyte percentage of red cells ( 27863252 32888494) Immature fraction of reticulocytes ( 27863252) Lymphocyte percentage of white cells ( 32888494) Mean corpuscular volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Monocyte percentage of white cells ( 32888494) Obesity-related traits ( 23251661) Plateletcrit ( 32888494) Red cell distribution width ( 28957414 32888494) Regular attendance at a religious group ( 29970889) Reticulocyte count ( 27863252 32888494) Reticulocyte fraction of red cells ( 27863252 32888494)
Interacting Genes		16 interacting genes: ASPSCR1 CDC42 GADD45G GRB7 MKNK1 NSFL1C OGT PDPK1 RAD23A RPS6KA1 TNFSF11 TULP3 UBXN2A VAV1 XPO1 ZWINT	4 interacting genes: DBI DYDC2 PHAX UBXN6
Entrez ID		51808	165324
HPRD ID		15122	10292
Ensembl ID		ENSG00000164902	ENSG00000173960
Uniprot IDs		Q9H814	P68543
PDB IDs		2XC7 8PNT
Enriched GO Terms of Interacting Partners?		Cytoplasm Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Regulation Of Protein Metabolic Process Regulation Of Proteasomal Protein Catabolic Process Ubiquitin Binding Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Golgi Organization Intracellular Signal Transduction Regulation Of Signal Transduction Nuclear Membrane Reassembly Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Cytosol Regulation Of Intracellular Signal Transduction Regulation Of Cell Cycle Positive Regulation Of Cell Activation Regulation Of Protein Catabolic Process Regulation Of Proteolysis Positive Regulation Of Intracellular Signal Transduction Regulation Of Translation Regulation Of Ubiquitin-dependent Protein Catabolic Process Regulation Of Cell Communication Regulation Of Signaling 3-phosphoinositide-dependent Protein Kinase Activity T Cell Costimulation Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Organelle Localization Nuclear Membrane Organization Cell Projection Positive Regulation Of Cell Adhesion Leukocyte Migration GBD Domain Binding Storage Vacuole Epidermal Growth Factor Receptor Signaling Pathway TORC1 Signaling Bronchus Morphogenesis Cellular Response To Triglyceride Negative Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Fever Generation By Positive Regulation Of Prostaglandin Secretion Knl1/Spc105 Complex Regulation Of Meiosis I Spindle Assembly Checkpoint Homologous Chromosome Orientation In Meiotic Metaphase I VCP-NSFL1C Complex Membrane Assembly Negative Regulation Of Protein Localization To Centrosome	Protein-lipid Complex Benzodiazepine Receptor Binding Negative Regulation Of Protein Lipidation Long-chain Fatty Acyl-CoA Binding SnRNA Export From Nucleus MRNA Cap Binding Complex Binding Regulation Of Protein Lipidation Negative Regulation Of Lipoprotein Metabolic Process Endosome To Lysosome Transport Via Multivesicular Body Sorting Pathway Regulation Of Lipoprotein Metabolic Process Phosphatidylcholine Acyl-chain Remodeling Fatty-acyl-CoA Binding Positive Regulation Of Phospholipid Transport Toxic Substance Binding Set1C/COMPASS Complex Perinuclear Endoplasmic Reticulum
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