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RPS6KA1 and MPP1
Number of citations of the paper that reports this interaction (PubMedID
21900206
)
0
Data Source:
BioGRID
(two hybrid)
RPS6KA1
MPP1
Description
ribosomal protein S6 kinase A1
MAGUK p55 scaffold protein 1
Image
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Synapse
Cytoskeleton
Plasma Membrane
Cell-cell Junction
Membrane
Cortical Cytoskeleton
Stereocilium
Centriolar Satellite
Cell Projection
Molecular Function
Nucleotide Binding
Magnesium Ion Binding
Protein Kinase Activity
Protein Serine/threonine Kinase Activity
Ribosomal Protein S6 Kinase Activity
Protein Serine/threonine/tyrosine Kinase Activity
Protein Binding
ATP Binding
Kinase Activity
Transferase Activity
Metal Ion Binding
Protein Serine Kinase Activity
GMP Kinase Activity
Signaling Receptor Binding
Protein Binding
Biological Process
Protein Phosphorylation
Signal Transduction
Chemical Synaptic Transmission
Positive Regulation Of Cell Growth
Negative Regulation Of TOR Signaling
Intracellular Signal Transduction
TORC1 Signaling
Negative Regulation Of Apoptotic Process
Regulation Of Translation In Response To Stress
Positive Regulation Of Cell Differentiation
Positive Regulation Of DNA-templated Transcription
Positive Regulation Of Transcription By RNA Polymerase II
Hepatocyte Proliferation
Positive Regulation Of Hepatic Stellate Cell Activation
Signal Transduction
GMP Metabolic Process
GDP Metabolic Process
Regulation Of Neutrophil Chemotaxis
Pathways
ERK/MAPK targets
CREB phosphorylation
Senescence-Associated Secretory Phenotype (SASP)
Senescence-Associated Secretory Phenotype (SASP)
Recycling pathway of L1
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling
RSK activation
RSK activation
Gastrin-CREB signalling pathway via PKC and MAPK
Transcriptional and post-translational regulation of MITF-M expression and activity
Sensory processing of sound by outer hair cells of the cochlea
Drugs
Purvalanol A
Fostamatinib
Diseases
GWAS
Amyotrophic lateral sclerosis (sporadic) (
24529757
)
Fasting plasma glucose (
31932636
)
Glucose homeostasis traits (
25524916
)
Lymphocyte count (
32888494
)
Mean corpuscular volume (
27863252
)
Mean reticulocyte volume (
32888494
)
Mean spheric corpuscular volume (
32888494
)
Rosacea symptom severity (
29771307
)
Triglyceride levels (
30108155
)
White blood cell count (
32888494
)
Hematology traits (
23263863
)
Mean corpuscular volume (
23263863
)
Red blood cell traits (
23446634
)
Interacting Genes
88 interacting genes:
ARHGEF11
ARHGEF12
ATM
ATXN3
BAD
CARHSP1
CCT4
CDKN1B
CEBPB
CFL1
CREB1
CREBBP
DDAH2
DEPTOR
DLC1
DLG4
EEF1D
EEF2K
ERBIN
ESR1
ETV1
FGFR1
FOS
GBP2
GMFB
GOPC
GORASP1
GORASP2
GRB2
GRID2IP
GSK3B
HTRA1
L1CAM
LIMK2
LNX1
MAGI1
MAGI2
MAGI3
MAPK1
MAPK3
MAPT
MAST1
MAST2
METTL1
MITF
MPP1
MTOR
MXD1
NFKBIA
NHERF2
NR4A1
NR4A2
NR4A3
PARD3B
PDCD4
PDPK1
PDZD7
PDZK1
PDZRN3
PDZRN4
PHAX
POLDIP3
PPM1G
PPP1R3A
PPP1R9A
PTPN3
RPTOR
SHANK3
SHROOM2
SNTA1
SNTB1
SNTG2
SNX27
SRF
SRSF5
STAT3
SYK
SYNJ2BP
TAMALIN
TOB2
TP53
TSC2
TTK
UBE2T
VCP
WHRN
YBX1
YWHAB
46 interacting genes:
ABCC4
ACER1
ACER2
AGPAT3
AMOTL2
AP2M1
APH1A
ATP5F1C
ATRAID
DERL2
DGAT2L6
DLG4
DNPEP
ERBIN
FXR2
GADD45A
GPRASP3
GSK3B
GYPC
HNRNPD
INCA1
KLHL12
MAP3K20
MEOX2
NR1H2
OGT
OPTN
PAQR8
PRIMPOL
RPRM
RPS6KA1
RPS6KA6
SGSM2
SLC35E1
SMN1
SRSF10
STK3
STUB1
SYNGR3
TK1
TMEM239
TRIM55
TRIM63
USP21
UXT
ZNF639
Entrez ID
6195
4354
HPRD ID
03402
02370
Ensembl ID
ENSG00000117676
ENSG00000130830
Uniprot IDs
Q15418
B4E325
Q00013
PDB IDs
2WNT
2Z7Q
2Z7R
2Z7S
3RNY
3TEI
4H3P
4NIF
5CSF
5CSI
5CSJ
5CSN
5N7D
5N7F
5N7G
5V61
5V62
6TWY
7P74
7PC8
7QQL
8WF4
8XOV
2EJY
2EV8
3NEY
Enriched GO Terms of Interacting Partners
?
Intracellular Signal Transduction
Signal Transduction
Intracellular Signaling Cassette
Cytoplasm
Phosphatase Binding
Regulation Of Cell Development
Positive Regulation Of Cellular Component Organization
Cellular Response To Oxygen-containing Compound
Regulation Of Cellular Component Organization
Nuclear Glucocorticoid Receptor Binding
Regulation Of Cell Population Proliferation
Regulation Of Cell Differentiation
Regulation Of Cellular Response To Heat
Positive Regulation Of Protein-containing Complex Assembly
Cellular Response To Nutrient Levels
TOR Signaling
Negative Regulation Of Signaling
Negative Regulation Of Cell Communication
Phosphorylation
Regulation Of Signaling
Regulation Of Cell Communication
Negative Regulation Of TOR Signaling
Regulation Of Multicellular Organismal Process
Cellular Response To Hormone Stimulus
Cellular Response To Peptide Hormone Stimulus
Protein Phosphorylation
Cellular Response To Stress
TORC1 Signaling
Regulation Of TORC1 Signaling
Negative Regulation Of TORC1 Signaling
Developmental Process
Negative Regulation Of Signal Transduction
Regulation Of Osteoclast Differentiation
Response To Peptide Hormone
Regulation Of Multicellular Organismal Development
Negative Regulation Of Autophagy
Response To Decreased Oxygen Levels
Regulation Of TOR Signaling
Negative Regulation Of Catabolic Process
Intracellular Protein Localization
Negative Regulation Of Intracellular Signal Transduction
Regulation Of Signal Transduction
Organelle Organization
Response To Oxygen Levels
Regulation Of Developmental Process
PDZ Domain Binding
Response To Nutrient Levels
Cellular Response To Cytokine Stimulus
Regulation Of Apoptotic Process
Regulation Of Intracellular Signal Transduction
Intracellular Signal Transduction
TOR Signaling
Ribosomal Protein S6 Kinase Activity
N-acylsphingosine Amidohydrolase Activity
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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