CLK1 and GOLM1

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
HPRD (two hybrid)

		CLK1	GOLM1
Gene Name		CDC-like kinase 1	golgi membrane protein 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm	Extracellular Space Golgi Apparatus Integral Component Of Plasma Membrane Extracellular Vesicular Exosome
	Molecular Function	Protein Serine/threonine Kinase Activity Protein Serine/threonine/tyrosine Kinase Activity Non-membrane Spanning Protein Tyrosine Kinase Activity ATP Binding	Protein Binding
	Biological Process	Cell Proliferation Peptidyl-serine Phosphorylation Peptidyl-threonine Phosphorylation Peptidyl-tyrosine Phosphorylation Regulation Of RNA Splicing Protein Autophosphorylation	Nucleus Organization Regulation Of Lipid Metabolic Process
Pathways
Drugs		Debromohymenialdisine ethyl 3-[(E)-2-amino-1-cyanoethenyl]-6,7-dichloro-1-methyl-1H-indole-2-carboxylate
Diseases
GWAS
Protein-Protein Interactions		20 interactors: BCLAF1 GOLM1 KRTAP10-7 LUC7L3 MBP NCOR1 PDE9A PIAS4 PPIG PRMT5 PRPF4 PTPN1 SAFB SRPK1 SRPK2 SRSF1 SRSF3 SRSF6 UBL5 YWHAG	26 interactors: B3GNT4 C1orf174 CIAO1 CLK1 DCK DCTN2 DEXI EFTUD2 EIF2B3 EIF3J ELAC2 FLOT1 FTH1 GEMIN7 GNB2L1 GRIK5 KCNE3 LSM12 MED22 NIPSNAP3A NRSN2 RPA2 RPL13A SLC40A1 SYT1 ZFAND3
Entrez ID		1195	51280
HPRD ID		09058	08428
Ensembl ID		ENSG00000013441	ENSG00000135052
Uniprot IDs		P49759	B3KNK9 Q8NBJ4
PDB IDs		1Z57 2VAG
Enriched GO Terms of Interacting Partners?		RNA Splicing MRNA Splicing, Via Spliceosome RNA Processing RNA Splicing, Via Transesterification Reactions MRNA Processing MRNA Metabolic Process RNA Metabolic Process Gene Expression Spliceosomal Complex Assembly Ribonucleoprotein Complex Assembly Regulation Of MRNA Splicing, Via Spliceosome Nucleobase-containing Compound Metabolic Process Regulation Of MRNA Processing Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of RNA Splicing Cellular Nitrogen Compound Metabolic Process MRNA Splice Site Selection Ribonucleoprotein Complex Biogenesis Termination Of RNA Polymerase II Transcription Nitrogen Compound Metabolic Process MRNA Export From Nucleus DNA-templated Transcription, Termination RNA Export From Nucleus MRNA 3'-end Processing RNA 3'-end Processing Cellular Macromolecular Complex Assembly Nuclear Export MRNA Transport Nucleus Organization Positive Regulation Of Viral Genome Replication RNA Transport Transcription, DNA-templated RNA Localization RNA Biosynthetic Process Positive Regulation Of Apoptotic Signaling Pathway Negative Regulation Of Viral Genome Replication Negative Regulation Of Cellular Metabolic Process Regulation Of Glycolytic Process By Negative Regulation Of Transcription From RNA Polymerase II Promoter Nuclear Speck Organization Peptidyl-tyrosine Dephosphorylation Involved In Inactivation Of Protein Kinase Activity Positive Regulation Of Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Response To DNA Damage Stimulus Nucleocytoplasmic Transport Nuclear Transport Positive Regulation Of Cell Death Cellular Metabolic Process Regulation Of Viral Genome Replication	Regulation Of Translational Initiation Negative Regulation Of Translation Regulation Of Translation Negative Regulation Of Translational Initiation Regulation Of Vesicle Fusion Posttranscriptional Regulation Of Gene Expression Mitochondrial TRNA 3'-trailer Cleavage, Endonucleolytic Negative Regulation Of Formation Of Translation Preinitiation Complex Fast, Calcium Ion-dependent Exocytosis Of Neurotransmitter Spleen Trabecula Formation Translational Initiation Intracellular Sequestering Of Iron Ion TRNA 3'-trailer Cleavage Positive Regulation Of CAMP Catabolic Process Iron Ion Transport Cellular Iron Ion Homeostasis Dicarboxylic Acid Transport Negative Regulation Of Hydrogen Peroxide-induced Neuron Death Mitochondrial RNA 3'-end Processing Cellular Homeostasis
Tagcloud ?		10q 11q 13q 14q 15q 1q 21q 2q 3p 3q 4q 6q 8q 9q aberration acsl1 ethnicities gains governing incurable karyotypes lyst malaysia malaysian myeloma nfkbia penetrance predispositions xq	16q 1q affymetrix classic clustering clusters cytoskeleton distinguished epithelium fresh frozen gpr137b hierarchical ilc lcis lobular mastectomy microarrays microdissected obligate personalize pik3r1 precursor prophylactic supervised transcriptomic triplets u133a unsupervised
Tagcloud (Difference) ?		10q 11q 13q 14q 15q 21q 2q 3p 3q 4q 6q 8q 9q aberration acsl1 ethnicities gains governing incurable karyotypes lyst malaysia malaysian myeloma nfkbia penetrance predispositions xq	16q affymetrix classic clustering clusters cytoskeleton distinguished epithelium fresh frozen gpr137b hierarchical ilc lcis lobular mastectomy microarrays microdissected obligate personalize pik3r1 precursor prophylactic supervised transcriptomic triplets u133a unsupervised
Tagcloud (Intersection) ?		1q