CLK1 and PPIG

Number of citations of the paper that reports this interaction (PMID 8973360)
14

Data Source:
HPRD (two hybrid)

		CLK1	PPIG
Gene Name		CDC-like kinase 1	peptidylprolyl isomerase G (cyclophilin G)
Image
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm	Nucleus Nucleoplasm Cytoplasm Nuclear Matrix Nuclear Speck
	Molecular Function	Protein Serine/threonine Kinase Activity Protein Serine/threonine/tyrosine Kinase Activity Non-membrane Spanning Protein Tyrosine Kinase Activity ATP Binding	Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding Cyclosporin A Binding Poly(A) RNA Binding
	Biological Process	Cell Proliferation Peptidyl-serine Phosphorylation Peptidyl-threonine Phosphorylation Peptidyl-tyrosine Phosphorylation Regulation Of RNA Splicing Protein Autophosphorylation	Protein Peptidyl-prolyl Isomerization Protein Folding RNA Splicing
Pathways
Drugs		Debromohymenialdisine ethyl 3-[(E)-2-amino-1-cyanoethenyl]-6,7-dichloro-1-methyl-1H-indole-2-carboxylate
Diseases
GWAS
Protein-Protein Interactions		20 interactors: BCLAF1 GOLM1 KRTAP10-7 LUC7L3 MBP NCOR1 PDE9A PIAS4 PPIG PRMT5 PRPF4 PTPN1 SAFB SRPK1 SRPK2 SRSF1 SRSF3 SRSF6 UBL5 YWHAG	25 interactors: BEND7 CACNA1A CEP70 CLK1 DAB1 DACH1 FHL3 KCTD6 LGALS3 NKAP PCBP1 PNMA2 PNN POLR2A PPCDC PRPF38A PRPF40A RBM39 SLU7 SMN2 SP1 TFCP2 THAP1 YWHAG ZCCHC10
Entrez ID		1195	9360
HPRD ID		09058	12083
Ensembl ID		ENSG00000013441	ENSG00000138398
Uniprot IDs		P49759	Q13427
PDB IDs		1Z57 2VAG	2GW2 2WFI 2WFJ
Enriched GO Terms of Interacting Partners?		RNA Splicing MRNA Splicing, Via Spliceosome RNA Processing RNA Splicing, Via Transesterification Reactions MRNA Processing MRNA Metabolic Process RNA Metabolic Process Gene Expression Spliceosomal Complex Assembly Ribonucleoprotein Complex Assembly Regulation Of MRNA Splicing, Via Spliceosome Nucleobase-containing Compound Metabolic Process Regulation Of MRNA Processing Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of RNA Splicing Cellular Nitrogen Compound Metabolic Process MRNA Splice Site Selection Ribonucleoprotein Complex Biogenesis Termination Of RNA Polymerase II Transcription Nitrogen Compound Metabolic Process MRNA Export From Nucleus DNA-templated Transcription, Termination RNA Export From Nucleus MRNA 3'-end Processing RNA 3'-end Processing Cellular Macromolecular Complex Assembly Nuclear Export MRNA Transport Nucleus Organization Positive Regulation Of Viral Genome Replication RNA Transport Transcription, DNA-templated RNA Localization RNA Biosynthetic Process Positive Regulation Of Apoptotic Signaling Pathway Negative Regulation Of Viral Genome Replication Negative Regulation Of Cellular Metabolic Process Regulation Of Glycolytic Process By Negative Regulation Of Transcription From RNA Polymerase II Promoter Nuclear Speck Organization Peptidyl-tyrosine Dephosphorylation Involved In Inactivation Of Protein Kinase Activity Positive Regulation Of Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Response To DNA Damage Stimulus Nucleocytoplasmic Transport Nuclear Transport Positive Regulation Of Cell Death Cellular Metabolic Process Regulation Of Viral Genome Replication	RNA Splicing MRNA Processing MRNA Metabolic Process RNA Processing RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Transcription Initiation From RNA Polymerase II Promoter Transcription, DNA-templated Positive Regulation Of Viral Transcription Adult Walking Behavior Cell-cell Adhesion Involved In Neuronal-glial Interactions Involved In Cerebral Cortex Radial Glia Guided Migration Cerebellar Molecular Layer Development Negative Regulation Of Immunological Synapse Formation Sequestering Of Nodal From Receptor Via Nodal Binding Cerebellum Morphogenesis RNA Biosynthetic Process Hindbrain Morphogenesis DNA-templated Transcription, Initiation Ventral Spinal Cord Development Spliceosomal Complex Assembly Vestibular Nucleus Development Negative Regulation Of Nodal Signaling Pathway Cerebellum Structural Organization Transcription, RNA-templated Negative Regulation Of T Cell Activation Via T Cell Receptor Contact With Antigen Bound To MHC Molecule On Antigen Presenting Cell Regulation Of Viral Transcription Cellular Metabolic Process Positive Regulation Of Viral Process Cerebellum Maturation Lateral Motor Column Neuron Migration RNA Polymerase II Transcriptional Preinitiation Complex Assembly Musculoskeletal Movement, Spinal Reflex Action Positive Regulation Of Mononuclear Cell Migration Spinal Cord Motor Neuron Migration Mononuclear Cell Migration Gamma-aminobutyric Acid Secretion Regulation Of RNA Splicing Cell Proliferation Radial Glia Guided Migration Of Purkinje Cell MRNA 3'-splice Site Recognition Negative Regulation Of Cell Proliferation Involved In Contact Inhibition Regulation Of Acetylcholine Secretion, Neurotransmission Spinal Cord Development
Tagcloud ?		10q 11q 13q 14q 15q 1q 21q 2q 3p 3q 4q 6q 8q 9q aberration acsl1 ethnicities gains governing incurable karyotypes lyst malaysia malaysian myeloma nfkbia penetrance predispositions xq
Tagcloud (Difference) ?		10q 11q 13q 14q 15q 1q 21q 2q 3p 3q 4q 6q 8q 9q aberration acsl1 ethnicities gains governing incurable karyotypes lyst malaysia malaysian myeloma nfkbia penetrance predispositions xq
Tagcloud (Intersection) ?