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CLK1 and PRPF4
Number of citations of the paper that reports this interaction (PMID
11418604
)
16
Data Source:
BioGRID
(pull down)
HPRD
(in vitro)
CLK1
PRPF4
Gene Name
CDC-like kinase 1
pre-mRNA processing factor 4
Image
Gene Ontology Annotations
Cellular Component
Nucleus
Cytoplasm
Nucleus
Nucleoplasm
Spliceosomal Complex
Cajal Body
Nuclear Speck
U4/U6 X U5 Tri-snRNP Complex
U4/U6 SnRNP
Molecular Function
Protein Serine/threonine Kinase Activity
Protein Serine/threonine/tyrosine Kinase Activity
Non-membrane Spanning Protein Tyrosine Kinase Activity
ATP Binding
Protein Binding
U6 SnRNA Binding
U4 SnRNA Binding
Biological Process
Cell Proliferation
Peptidyl-serine Phosphorylation
Peptidyl-threonine Phosphorylation
Peptidyl-tyrosine Phosphorylation
Regulation Of RNA Splicing
Protein Autophosphorylation
RNA Splicing, Via Transesterification Reactions
MRNA Splicing, Via Spliceosome
RNA Processing
RNA Splicing
Gene Expression
Pathways
Processing of Capped Intron-Containing Pre-mRNA
mRNA Splicing
mRNA Splicing - Major Pathway
Drugs
Debromohymenialdisine
ethyl 3-[(E)-2-amino-1-cyanoethenyl]-6,7-dichloro-1-methyl-1H-indole-2-carboxylate
Diseases
GWAS
Protein-Protein Interactions
20 interactors:
BCLAF1
GOLM1
KRTAP10-7
LUC7L3
MBP
NCOR1
PDE9A
PIAS4
PPIG
PRMT5
PRPF4
PTPN1
SAFB
SRPK1
SRPK2
SRSF1
SRSF3
SRSF6
UBL5
YWHAG
12 interactors:
APP
ATP5J2
CLK1
GPKOW
NHP2L1
PPIH
PRPF3
PRPF31
SRSF1
TGFBR1
U2AF1
WBP4
Entrez ID
1195
9128
HPRD ID
09058
08479
Ensembl ID
ENSG00000013441
ENSG00000136875
Uniprot IDs
P49759
O43172
Q5T1M7
PDB IDs
1Z57
2VAG
1MZW
Enriched GO Terms of Interacting Partners
?
RNA Splicing
MRNA Splicing, Via Spliceosome
RNA Processing
RNA Splicing, Via Transesterification Reactions
MRNA Processing
MRNA Metabolic Process
RNA Metabolic Process
Gene Expression
Spliceosomal Complex Assembly
Ribonucleoprotein Complex Assembly
Regulation Of MRNA Splicing, Via Spliceosome
Nucleobase-containing Compound Metabolic Process
Regulation Of MRNA Processing
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Regulation Of RNA Splicing
Cellular Nitrogen Compound Metabolic Process
MRNA Splice Site Selection
Ribonucleoprotein Complex Biogenesis
Termination Of RNA Polymerase II Transcription
Nitrogen Compound Metabolic Process
MRNA Export From Nucleus
DNA-templated Transcription, Termination
RNA Export From Nucleus
MRNA 3'-end Processing
RNA 3'-end Processing
Cellular Macromolecular Complex Assembly
Nuclear Export
MRNA Transport
Nucleus Organization
Positive Regulation Of Viral Genome Replication
RNA Transport
Transcription, DNA-templated
RNA Localization
RNA Biosynthetic Process
Positive Regulation Of Apoptotic Signaling Pathway
Negative Regulation Of Viral Genome Replication
Negative Regulation Of Cellular Metabolic Process
Regulation Of Glycolytic Process By Negative Regulation Of Transcription From RNA Polymerase II Promoter
Nuclear Speck Organization
Peptidyl-tyrosine Dephosphorylation Involved In Inactivation Of Protein Kinase Activity
Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Positive Regulation Of Apoptotic Process
Positive Regulation Of Programmed Cell Death
Positive Regulation Of Response To DNA Damage Stimulus
Nucleocytoplasmic Transport
Nuclear Transport
Positive Regulation Of Cell Death
Cellular Metabolic Process
Regulation Of Viral Genome Replication
MRNA Processing
MRNA Splicing, Via Spliceosome
RNA Splicing, Via Transesterification Reactions
MRNA Metabolic Process
RNA Processing
RNA Splicing
MRNA 3'-end Processing
Spliceosomal Tri-snRNP Complex Assembly
Ribonucleoprotein Complex Biogenesis
RNA 3'-end Processing
MRNA Cis Splicing, Via Spliceosome
RNA Metabolic Process
Nucleobase-containing Compound Metabolic Process
Gene Expression
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Ribonucleoprotein Complex Assembly
Cellular Nitrogen Compound Metabolic Process
Spliceosomal SnRNP Assembly
Termination Of RNA Polymerase II Transcription
Nitrogen Compound Metabolic Process
Peptidyl-threonine Phosphorylation
MRNA Export From Nucleus
DNA-templated Transcription, Termination
RNA Export From Nucleus
Cellular Metabolic Process
Synaptic Growth At Neuromuscular Junction
Regulation Of RNA Splicing
Collateral Sprouting In Absence Of Injury
Cellular Component Assembly
Peptidyl-serine Phosphorylation
Nuclear Export
MRNA Transport
RNA Transport
Regulation Of Protein Binding
Collateral Sprouting
Axon Midline Choice Point Recognition
MRNA 5'-splice Site Recognition
RNA Localization
Smooth Endoplasmic Reticulum Calcium Ion Homeostasis
Axon Choice Point Recognition
Cellular Macromolecular Complex Assembly
Parathyroid Gland Development
Neuron Remodeling
Intracellular Transport
Endothelial Cell Activation
Tagcloud
?
10q
11q
13q
14q
15q
1q
21q
2q
3p
3q
4q
6q
8q
9q
aberration
acsl1
ethnicities
gains
governing
incurable
karyotypes
lyst
malaysia
malaysian
myeloma
nfkbia
penetrance
predispositions
xq
Tagcloud (Difference)
?
10q
11q
13q
14q
15q
1q
21q
2q
3p
3q
4q
6q
8q
9q
aberration
acsl1
ethnicities
gains
governing
incurable
karyotypes
lyst
malaysia
malaysian
myeloma
nfkbia
penetrance
predispositions
xq
Tagcloud (Intersection)
?