THOC5

Gene Name		THO complex 5
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Transcription Export Complex THO Complex THO Complex Part Of Transcription Export Complex Nucleus Nucleoplasm Cytoplasm Nuclear Speck
	Molecular Function	MRNA Binding Protein Binding
	Biological Process	Cell Morphogenesis Blastocyst Development MRNA Processing MRNA Export From Nucleus RNA Splicing Regulation Of MRNA Export From Nucleus Stem Cell Division Monocyte Differentiation Positive Regulation Of DNA-templated Transcription, Elongation Negative Regulation Of Macrophage Differentiation Viral MRNA Export From Host Cell Nucleus Primitive Hemopoiesis Negative Regulation Of DNA Damage Checkpoint Regulation Of Stem Cell Division
Pathways
Drugs
Diseases
GWAS		Carotid atherosclerosis in HIV infection ( 20009918)
Protein-protein Interactions		11 interactors: CSF1R CSNK2A1 DDX39B LIG4 LSM3 NXF1 PPIL1 PRKCA THOC1 THOC7 ZNF830
Entrez ID		8563
HPRD ID		16650
Ensembl ID		ENSG00000100296
Uniprot IDs		Q13769
PDB IDs
Enriched GO Terms of Interacting Partners?		Viral MRNA Export From Host Cell Nucleus MRNA Export From Nucleus RNA Export From Nucleus MRNA Transport Nuclear Export Intracellular Transport Of Virus RNA Splicing RNA Transport RNA Localization MRNA Processing Negative Regulation Of DNA Damage Checkpoint MRNA Metabolic Process Viral Process RNA Processing Nucleocytoplasmic Transport Nuclear Transport Regulation Of DNA Damage Checkpoint Gene Expression Regulation Of Cell Cycle Negative Regulation Of Cell Cycle Positive Regulation Of DNA-templated Transcription, Elongation Viral Life Cycle Regulation Of Cell Cycle Checkpoint MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Cytoplasmic Transport DNA Replication Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of DNA-templated Transcription, Elongation Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Cell Proliferation DNA Ligation Involved In DNA Recombination Positive Regulation Of Dense Core Granule Biogenesis Negative Regulation Of Isotype Switching To IgA Isotypes Nitrogen Compound Metabolic Process Apoptotic Process Regulation Of Mitotic Cell Cycle Programmed Cell Death Histone H3-T6 Phosphorylation Macrophage Colony-stimulating Factor Signaling Pathway Cell Death Death DNA-dependent DNA Replication Regulation Of Cell Cycle Process Cellular Metabolic Process Intestinal Epithelial Structure Maintenance RNA Secondary Structure Unwinding
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