THOC5 and ZNF830

Number of citations: 0 (PubMedID 22365833)
Data Source: BioGRID (two hybrid)

		THOC5	ZNF830
Name		THO complex subunit 5	zinc finger protein 830
Structure			No pdb structure
GO Annotations	Cellular Component	Transcription Export Complex THO Complex THO Complex Part Of Transcription Export Complex Chromosome, Telomeric Region Nucleus Nucleoplasm Cytoplasm	Nucleus Nucleoplasm Spliceosomal Complex Chromosome Nuclear Speck
	Molecular Function	RNA Binding MRNA Binding Protein Binding	Nucleic Acid Binding Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	MRNA Processing MRNA Export From Nucleus RNA Splicing Cell Differentiation Monocyte Differentiation MRNA Transport Primitive Hemopoiesis	Mitotic Cell Cycle Ovarian Follicle Development Preantral Ovarian Follicle Growth Blastocyst Growth RNA Processing MRNA Processing RNA Splicing Nuclear DNA Replication Mitotic DNA Replication Checkpoint Signaling Negative Regulation Of Apoptotic Process Mitotic DNA Damage Checkpoint Signaling Chromosome Organization Cell Division Intestinal Epithelial Structure Maintenance
Pathways		Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA 3'-end processing RNA Polymerase II Transcription Termination Signaling by CSF1 (M-CSF) in myeloid cells	Formation of TC-NER Pre-Incision Complex Transcription-Coupled Nucleotide Excision Repair (TC-NER) Dual incision in TC-NER Gap-filling DNA repair synthesis and ligation in TC-NER mRNA Splicing - Major Pathway
GWAS		Apolipoprotein A1 levels ( 32203549 ) Carotid atherosclerosis in HIV infection ( 20009918 ) HDL cholesterol levels ( 32203549 ) Lipid traits ( 24023261 )	Night sleep phenotypes ( 27126917 )
Novel Interactors		None recorded	1 novel interactors: ZPBP2
Interacting Genes		11 interacting genes: CSF1R CSNK2A1 HSPB1 LIG4 LSM3 NXF1 OXTR PPIL1 PRKCA THOC7 ZNF830	11 interacting genes: CLK1 FRA10AC1 ILF3 LARP4 PCBP1 PCM1 PPIL2 PRPF8 RAB4A SESTD1 THOC5
Entrez ID		8563	91603
HPRD ID		16650	14469
Ensembl ID		ENSG00000100296	ENSG00000198783
Uniprot IDs		Q13769	Q96NB3
PDB IDs		7APK 7ZNK 7ZNL	Not available
GO Terms Enriched among Interactors		Negative Regulation Of Programmed Cell Death Negative Regulation Of Apoptotic Process Double-strand Break Repair Via Classical Nonhomologous End Joining MRNA Metabolic Process Transcription Export Complex Nucleoplasm RNA Splicing Regulation Of Programmed Cell Death Regulation Of Apoptotic Process MRNA Processing Spliceosomal Complex Regulation Of Bone Resorption Protein Folding Regulation Of Bone Remodeling Double-strand Break Repair Via Nonhomologous End Joining Negative Regulation Of Protein Kinase C Signaling Establishment Of Integrated Proviral Latency Oxytocin Receptor Activity Nucleic Acid Metabolic Process Positive Regulation Of Blood Vessel Endothelial Cell Migration MRNA Export From Nucleus Positive Regulation Of Cell Population Proliferation CSF1-CSF1R Complex Positive Regulation Of Multicellular Organismal Process Macrophage Colony-stimulating Factor Receptor Activity Regulation Of Tissue Remodeling Macrophage Colony-stimulating Factor Signaling Pathway Regulation Of Translational Initiation Nucleobase-containing Compound Metabolic Process Protein Kinase CK2 Complex RNA Metabolic Process Symbiont-mediated Disruption Of Host Cell PML Body Regulation Of Translation DNA Damage Checkpoint Signaling Protein Kinase C Inhibitor Activity Positive Regulation Of Endothelial Cell Migration Regulation Of Blood Vessel Endothelial Cell Migration DNA Ligase (ATP) Activity DNA Ligase IV Complex Pro-B Cell Differentiation T Cell Receptor V(D)J Recombination Establishment Of Viral Latency DNA Ligase Activity DN2 Thymocyte Differentiation Calcium,diacylglycerol-dependent Serine/threonine Kinase Activity Positive Regulation Of Dense Core Granule Biogenesis Positive Regulation Of Angiotensin-activated Signaling Pathway Histone H3T6 Kinase Activity Alphav-beta3 Integrin-PKCalpha Complex Protein Kinase C Signaling	RNA Splicing MRNA Processing MRNA Metabolic Process RNA Metabolic Process RNA Processing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions