THOC5 and ZNF830

Number of citations of the paper that reports this interaction (PMID 22365833)
24

Data Source:
BioGRID (two hybrid)

		THOC5	ZNF830
Gene Name		THO complex 5	zinc finger protein 830
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Transcription Export Complex THO Complex THO Complex Part Of Transcription Export Complex Nucleus Nucleoplasm Cytoplasm Nuclear Speck	Nucleoplasm Cytoplasm Nuclear Speck
	Molecular Function	MRNA Binding Protein Binding	Protein Binding Metal Ion Binding
	Biological Process	Cell Morphogenesis Blastocyst Development MRNA Processing MRNA Export From Nucleus RNA Splicing Regulation Of MRNA Export From Nucleus Stem Cell Division Monocyte Differentiation Positive Regulation Of DNA-templated Transcription, Elongation Negative Regulation Of Macrophage Differentiation Viral MRNA Export From Host Cell Nucleus Primitive Hemopoiesis Negative Regulation Of DNA Damage Checkpoint Regulation Of Stem Cell Division	Blastocyst Growth Mitotic Nuclear Division Nuclear DNA Replication Mitotic DNA Damage Checkpoint Chromosome Organization Cell Division Intestinal Epithelial Structure Maintenance
Pathways
Drugs
Diseases
GWAS		Carotid atherosclerosis in HIV infection ( 20009918)
Protein-Protein Interactions		11 interactors: CSF1R CSNK2A1 DDX39B LIG4 LSM3 NXF1 PPIL1 PRKCA THOC1 THOC7 ZNF830	6 interactors: FRA10AC1 ILF3 PCBP1 PRPF8 RAB4A THOC5
Entrez ID		8563	91603
HPRD ID		16650	14469
Ensembl ID		ENSG00000100296	ENSG00000198783
Uniprot IDs		Q13769	Q96NB3
PDB IDs
Enriched GO Terms of Interacting Partners?		Viral MRNA Export From Host Cell Nucleus MRNA Export From Nucleus RNA Export From Nucleus MRNA Transport Nuclear Export Intracellular Transport Of Virus RNA Splicing RNA Transport RNA Localization MRNA Processing Negative Regulation Of DNA Damage Checkpoint MRNA Metabolic Process Viral Process RNA Processing Nucleocytoplasmic Transport Nuclear Transport Regulation Of DNA Damage Checkpoint Gene Expression Regulation Of Cell Cycle Negative Regulation Of Cell Cycle Positive Regulation Of DNA-templated Transcription, Elongation Viral Life Cycle Regulation Of Cell Cycle Checkpoint MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Cytoplasmic Transport DNA Replication Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of DNA-templated Transcription, Elongation Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Cell Proliferation DNA Ligation Involved In DNA Recombination Positive Regulation Of Dense Core Granule Biogenesis Negative Regulation Of Isotype Switching To IgA Isotypes Nitrogen Compound Metabolic Process Apoptotic Process Regulation Of Mitotic Cell Cycle Programmed Cell Death Histone H3-T6 Phosphorylation Macrophage Colony-stimulating Factor Signaling Pathway Cell Death Death DNA-dependent DNA Replication Regulation Of Cell Cycle Process Cellular Metabolic Process Intestinal Epithelial Structure Maintenance RNA Secondary Structure Unwinding	RNA Splicing MRNA Processing MRNA Metabolic Process RNA Processing Regulation Of Stem Cell Division Negative Regulation Of DNA Damage Checkpoint MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Regulation Of MRNA Export From Nucleus Primitive Hemopoiesis RNA Metabolic Process Viral MRNA Export From Host Cell Nucleus Negative Regulation Of Macrophage Differentiation Gene Expression Regulation Of RNA Export From Nucleus Regulation Of DNA Damage Checkpoint Spliceosomal Tri-snRNP Complex Assembly Monocyte Differentiation Intracellular Transport Of Virus Nucleobase-containing Compound Metabolic Process Positive Regulation Of DNA-templated Transcription, Elongation Embryonic Hemopoiesis Immune System Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Cell Cycle Checkpoint Cellular Nitrogen Compound Metabolic Process Stem Cell Division Negative Regulation Of Viral Genome Replication Spliceosomal SnRNP Assembly
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