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ACKR4 and CCL25
Number of citations of the paper that reports this interaction (PMID
10706668
)
23
Data Source:
HPRD
(in vitro)
ACKR4
CCL25
Gene Name
atypical chemokine receptor 4
chemokine (C-C motif) ligand 25
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Early Endosome
Plasma Membrane
Integral Component Of Plasma Membrane
Recycling Endosome
Extracellular Region
Extracellular Space
Molecular Function
Chemokine Receptor Activity
Scavenger Receptor Activity
Protein Binding
Chemokine Binding
Hormone Activity
Chemokine Activity
CCR10 Chemokine Receptor Binding
Chemokine Receptor Binding
Biological Process
Receptor-mediated Endocytosis
Chemotaxis
Immune Response
G-protein Coupled Receptor Signaling Pathway
Chemokine-mediated Signaling Pathway
Positive Regulation Of Cell-matrix Adhesion
Chemotaxis
Inflammatory Response
Immune Response
Cell Surface Receptor Signaling Pathway
G-protein Coupled Receptor Signaling Pathway
Leukocyte Migration
Cell Chemotaxis
Negative Regulation Of Leukocyte Tethering Or Rolling
Pathways
Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD)
Signaling by GPCR
Peptide ligand-binding receptors
Chemokine receptors bind chemokines
Class A/1 (Rhodopsin-like receptors)
Metabolic disorders of biological oxidation enzymes
GPCR ligand binding
Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD)
Signaling by GPCR
GPCR downstream signaling
Peptide ligand-binding receptors
Chemokine receptors bind chemokines
Class A/1 (Rhodopsin-like receptors)
G alpha (i) signalling events
Metabolic disorders of biological oxidation enzymes
GPCR ligand binding
Drugs
Diseases
GWAS
Protein-Protein Interactions
11 interactors:
CCL11
CCL13
CCL19
CCL2
CCL21
CCL25
CCL5
CCL7
CCL8
CDK2
CXCL13
4 interactors:
ACKR2
ACKR4
CCR10
CCR9
Entrez ID
51554
6370
HPRD ID
07298
03976
Ensembl ID
ENSG00000129048
ENSG00000131142
Uniprot IDs
Q9NPB9
O15444
PDB IDs
Enriched GO Terms of Interacting Partners
?
Cell Chemotaxis
Leukocyte Chemotaxis
Leukocyte Migration
Inflammatory Response
Cellular Calcium Ion Homeostasis
Calcium Ion Homeostasis
Chemotaxis
Cellular Metal Ion Homeostasis
Cellular Cation Homeostasis
Regulation Of Leukocyte Migration
Cellular Ion Homeostasis
Metal Ion Homeostasis
Cell Migration
Cell Motility
Cellular Chemical Homeostasis
Ion Homeostasis
Positive Regulation Of Leukocyte Chemotaxis
Cellular Homeostasis
Positive Regulation Of Leukocyte Migration
Regulation Of Lymphocyte Migration
Locomotion
Eosinophil Chemotaxis
Immune Response
Eosinophil Migration
Defense Response
Positive Regulation Of Chemotaxis
Chemical Homeostasis
Positive Regulation Of Behavior
Movement Of Cell Or Subcellular Component
Regulation Of Chemotaxis
Regulation Of Cell Migration
Positive Regulation Of Cell Migration
Granulocyte Chemotaxis
Positive Regulation Of Cell Motility
Regulation Of Cell Motility
Positive Regulation Of Cellular Component Movement
Positive Regulation Of Locomotion
Regulation Of Locomotion
Response To External Stimulus
Regulation Of Cellular Component Movement
Regulation Of Behavior
Homeostatic Process
Immune System Process
Response To Stress
Regulation Of Granulocyte Chemotaxis
Regulation Of Cell-cell Adhesion
Positive Regulation Of Cell Adhesion
Dendritic Cell Chemotaxis
Monocyte Chemotaxis
Positive Regulation Of Cell-cell Adhesion
Chemokine-mediated Signaling Pathway
Cytokine-mediated Signaling Pathway
Cellular Response To Cytokine Stimulus
Chemotaxis
Response To Cytokine
Neutrophil Activation
G-protein Coupled Receptor Signaling Pathway
Locomotion
Immune Response
Receptor-mediated Endocytosis
Response To External Stimulus
Cellular Response To Organic Substance
Immune System Process
Endocytosis
Response To Organic Substance
Positive Regulation Of Cytosolic Calcium Ion Concentration
Cell Surface Receptor Signaling Pathway
Cytosolic Calcium Ion Homeostasis
Defense Response
Vesicle-mediated Transport
Cellular Calcium Ion Homeostasis
Calcium Ion Homeostasis
Cellular Metal Ion Homeostasis
Inflammatory Response
Cellular Cation Homeostasis
Cellular Ion Homeostasis
Metal Ion Homeostasis
Signal Transduction
Leukocyte Activation
Cellular Chemical Homeostasis
Signaling
Ion Homeostasis
Cell Communication
Cell Activation
Cellular Homeostasis
Cellular Response To Stimulus
Chemical Homeostasis
Cellular Defense Response
Response To Stress
Response To Stimulus
Homeostatic Process
Transport
Tagcloud
?
17f
28a
6ckine
ccl13
ccl14
ccl16
ccl17
ccl18
ccl19
ccl21
ccl22
ccl23
ccl26
ccl27
ccl28
ccl7
ccl8
ctack
cxcl11
cxcl3
cxcl7
il18
lymphotactin
mpif
parc
tarc
teck
tnfsf14
xcl1
Tagcloud (Difference)
?
17f
28a
6ckine
ccl13
ccl14
ccl16
ccl17
ccl18
ccl19
ccl21
ccl22
ccl23
ccl26
ccl27
ccl28
ccl7
ccl8
ctack
cxcl11
cxcl3
cxcl7
il18
lymphotactin
mpif
parc
tarc
teck
tnfsf14
xcl1
Tagcloud (Intersection)
?