CCL25 and CCR9

Number of citations of the paper that reports this interaction (PMID 10229797)
23

Data Source:
HPRD (in vivo, in vitro)

		CCL25	CCR9
Gene Name		chemokine (C-C motif) ligand 25	chemokine (C-C motif) receptor 9
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Extracellular Space	Plasma Membrane Integral Component Of Plasma Membrane Cell Surface
	Molecular Function	Hormone Activity Chemokine Activity CCR10 Chemokine Receptor Binding Chemokine Receptor Binding	Chemokine Receptor Activity C-C Chemokine Receptor Activity
	Biological Process	Positive Regulation Of Cell-matrix Adhesion Chemotaxis Inflammatory Response Immune Response Cell Surface Receptor Signaling Pathway G-protein Coupled Receptor Signaling Pathway Leukocyte Migration Cell Chemotaxis Negative Regulation Of Leukocyte Tethering Or Rolling	Chemotaxis Immune Response Cellular Defense Response G-protein Coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Chemokine-mediated Signaling Pathway
Pathways		Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR GPCR downstream signaling Peptide ligand-binding receptors Chemokine receptors bind chemokines Class A/1 (Rhodopsin-like receptors) G alpha (i) signalling events Metabolic disorders of biological oxidation enzymes GPCR ligand binding	Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR GPCR downstream signaling Peptide ligand-binding receptors Chemokine receptors bind chemokines Class A/1 (Rhodopsin-like receptors) G alpha (i) signalling events Metabolic disorders of biological oxidation enzymes GPCR ligand binding
Drugs
Diseases
GWAS			Celiac disease ( 20190752)
Protein-Protein Interactions		4 interactors: ACKR2 ACKR4 CCR10 CCR9	1 interactors: CCL25
Entrez ID		6370	10803
HPRD ID		03976	09200
Ensembl ID		ENSG00000131142	ENSG00000173585
Uniprot IDs		O15444	B2R734 P51686
PDB IDs
Enriched GO Terms of Interacting Partners?		Chemokine-mediated Signaling Pathway Cytokine-mediated Signaling Pathway Cellular Response To Cytokine Stimulus Chemotaxis Response To Cytokine Neutrophil Activation G-protein Coupled Receptor Signaling Pathway Locomotion Immune Response Receptor-mediated Endocytosis Response To External Stimulus Cellular Response To Organic Substance Immune System Process Endocytosis Response To Organic Substance Positive Regulation Of Cytosolic Calcium Ion Concentration Cell Surface Receptor Signaling Pathway Cytosolic Calcium Ion Homeostasis Defense Response Vesicle-mediated Transport Cellular Calcium Ion Homeostasis Calcium Ion Homeostasis Cellular Metal Ion Homeostasis Inflammatory Response Cellular Cation Homeostasis Cellular Ion Homeostasis Metal Ion Homeostasis Signal Transduction Leukocyte Activation Cellular Chemical Homeostasis Signaling Ion Homeostasis Cell Communication Cell Activation Cellular Homeostasis Cellular Response To Stimulus Chemical Homeostasis Cellular Defense Response Response To Stress Response To Stimulus Homeostatic Process Transport	Negative Regulation Of Leukocyte Tethering Or Rolling Negative Regulation Of Leukocyte Migration Positive Regulation Of Cell-matrix Adhesion Negative Regulation Of Leukocyte Cell-cell Adhesion Regulation Of Leukocyte Migration Regulation Of Cell-matrix Adhesion Positive Regulation Of Cell-substrate Adhesion Negative Regulation Of Cell-cell Adhesion Cell Chemotaxis Regulation Of Cell-substrate Adhesion Negative Regulation Of Cell Migration Negative Regulation Of Cell Adhesion Negative Regulation Of Cell Motility Leukocyte Migration Negative Regulation Of Cellular Component Movement Negative Regulation Of Locomotion Regulation Of Cell-cell Adhesion Positive Regulation Of Cell Adhesion Negative Regulation Of Immune System Process Inflammatory Response
Tagcloud ?		17f 28a 6ckine ccl13 ccl14 ccl16 ccl17 ccl18 ccl19 ccl21 ccl22 ccl23 ccl26 ccl27 ccl28 ccl7 ccl8 ctack cxcl11 cxcl3 cxcl7 il18 lymphotactin mpif parc tarc teck tnfsf14 xcl1	adoptive airway allergic alum ameliorated capg ccr5 cd25 foxp3 garp gzmb homing igg1 inf klrg1 lavage migrate migrated ova ovalbumin ox40 parasite parasites sorter spiralis treg trichinella uninfected veins
Tagcloud (Difference) ?		17f 28a 6ckine ccl13 ccl14 ccl16 ccl17 ccl18 ccl19 ccl21 ccl22 ccl23 ccl26 ccl27 ccl28 ccl7 ccl8 ctack cxcl11 cxcl3 cxcl7 il18 lymphotactin mpif parc tarc teck tnfsf14 xcl1	adoptive airway allergic alum ameliorated capg ccr5 cd25 foxp3 garp gzmb homing igg1 inf klrg1 lavage migrate migrated ova ovalbumin ox40 parasite parasites sorter spiralis treg trichinella uninfected veins
Tagcloud (Intersection) ?