CCL25 and CCR10

Number of citations of the paper that reports this interaction (PMID 10706668)
23

Data Source:
HPRD (in vitro)

		CCL25	CCR10
Gene Name		chemokine (C-C motif) ligand 25	chemokine (C-C motif) receptor 10
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Extracellular Space	Plasma Membrane Integral Component Of Plasma Membrane Cell Surface
	Molecular Function	Hormone Activity Chemokine Activity CCR10 Chemokine Receptor Binding Chemokine Receptor Binding	G-protein Coupled Receptor Activity C-C Chemokine Receptor Activity
	Biological Process	Positive Regulation Of Cell-matrix Adhesion Chemotaxis Inflammatory Response Immune Response Cell Surface Receptor Signaling Pathway G-protein Coupled Receptor Signaling Pathway Leukocyte Migration Cell Chemotaxis Negative Regulation Of Leukocyte Tethering Or Rolling	Chemotaxis Immune Response G-protein Coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Chemokine-mediated Signaling Pathway
Pathways		Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR GPCR downstream signaling Peptide ligand-binding receptors Chemokine receptors bind chemokines Class A/1 (Rhodopsin-like receptors) G alpha (i) signalling events Metabolic disorders of biological oxidation enzymes GPCR ligand binding	Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR GPCR downstream signaling Peptide ligand-binding receptors Chemokine receptors bind chemokines Class A/1 (Rhodopsin-like receptors) G alpha (i) signalling events Metabolic disorders of biological oxidation enzymes GPCR ligand binding
Drugs
Diseases
GWAS
Protein-Protein Interactions		4 interactors: ACKR2 ACKR4 CCR10 CCR9	10 interactors: CCL19 CCL2 CCL21 CCL25 CCL27 CCL28 CCL7 CCR7 CXCL13 PRRC2A
Entrez ID		6370	2826
HPRD ID		03976	02586
Ensembl ID		ENSG00000131142
Uniprot IDs		O15444	P46092
PDB IDs
Enriched GO Terms of Interacting Partners?		Chemokine-mediated Signaling Pathway Cytokine-mediated Signaling Pathway Cellular Response To Cytokine Stimulus Chemotaxis Response To Cytokine Neutrophil Activation G-protein Coupled Receptor Signaling Pathway Locomotion Immune Response Receptor-mediated Endocytosis Response To External Stimulus Cellular Response To Organic Substance Immune System Process Endocytosis Response To Organic Substance Positive Regulation Of Cytosolic Calcium Ion Concentration Cell Surface Receptor Signaling Pathway Cytosolic Calcium Ion Homeostasis Defense Response Vesicle-mediated Transport Cellular Calcium Ion Homeostasis Calcium Ion Homeostasis Cellular Metal Ion Homeostasis Inflammatory Response Cellular Cation Homeostasis Cellular Ion Homeostasis Metal Ion Homeostasis Signal Transduction Leukocyte Activation Cellular Chemical Homeostasis Signaling Ion Homeostasis Cell Communication Cell Activation Cellular Homeostasis Cellular Response To Stimulus Chemical Homeostasis Cellular Defense Response Response To Stress Response To Stimulus Homeostatic Process Transport	Cell Chemotaxis Regulation Of Leukocyte Migration Chemotaxis Positive Regulation Of Leukocyte Chemotaxis Cell Migration Positive Regulation Of Leukocyte Migration Cell Motility Leukocyte Migration Leukocyte Chemotaxis Positive Regulation Of Chemotaxis Regulation Of Cell Migration Cellular Calcium Ion Homeostasis Positive Regulation Of Behavior Calcium Ion Homeostasis Regulation Of Cell Motility Regulation Of Chemotaxis Locomotion Regulation Of Locomotion Immune Response Regulation Of Cellular Component Movement Positive Regulation Of Cell Adhesion Cellular Metal Ion Homeostasis Movement Of Cell Or Subcellular Component Regulation Of Behavior Inflammatory Response Cellular Cation Homeostasis Regulation Of Dendritic Cell Dendrite Assembly Cellular Ion Homeostasis Metal Ion Homeostasis Negative Regulation Of Leukocyte Migration Cellular Chemical Homeostasis Response To External Stimulus Negative Regulation Of Leukocyte Tethering Or Rolling Ion Homeostasis Regulation Of Cell Adhesion Regulation Of Lymphocyte Migration Immune System Process Regulation Of Granulocyte Chemotaxis Positive Regulation Of Cell Migration Establishment Of T Cell Polarity Positive Regulation Of Cell Motility Cellular Homeostasis Regulation Of Immune System Process Positive Regulation Of Cellular Component Movement Positive Regulation Of Locomotion Regulation Of Cell-cell Adhesion Positive Regulation Of Cytosolic Calcium Ion Concentration Positive Regulation Of Dendritic Cell Antigen Processing And Presentation Chemical Homeostasis Positive Regulation Of Cell-matrix Adhesion
Tagcloud ?		17f 28a 6ckine ccl13 ccl14 ccl16 ccl17 ccl18 ccl19 ccl21 ccl22 ccl23 ccl26 ccl27 ccl28 ccl7 ccl8 ctack cxcl11 cxcl3 cxcl7 il18 lymphotactin mpif parc tarc teck tnfsf14 xcl1	allograft allografts alloreactivity archived arrays augur cd138 cd154 cd19 cd27 existed ig iga igg igll1 immunocyte immunocytes intestine itx mucosal prone protracted reconstitution rejecting rejection repopulation serial stap1 undergoes
Tagcloud (Difference) ?		17f 28a 6ckine ccl13 ccl14 ccl16 ccl17 ccl18 ccl19 ccl21 ccl22 ccl23 ccl26 ccl27 ccl28 ccl7 ccl8 ctack cxcl11 cxcl3 cxcl7 il18 lymphotactin mpif parc tarc teck tnfsf14 xcl1	allograft allografts alloreactivity archived arrays augur cd138 cd154 cd19 cd27 existed ig iga igg igll1 immunocyte immunocytes intestine itx mucosal prone protracted reconstitution rejecting rejection repopulation serial stap1 undergoes
Tagcloud (Intersection) ?