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ACKR4
Gene Name
atypical chemokine receptor 4
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Early Endosome
Plasma Membrane
Integral Component Of Plasma Membrane
Recycling Endosome
Molecular Function
Chemokine Receptor Activity
Scavenger Receptor Activity
Protein Binding
Chemokine Binding
Biological Process
Receptor-mediated Endocytosis
Chemotaxis
Immune Response
G-protein Coupled Receptor Signaling Pathway
Chemokine-mediated Signaling Pathway
Pathways
Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD)
Signaling by GPCR
Peptide ligand-binding receptors
Chemokine receptors bind chemokines
Class A/1 (Rhodopsin-like receptors)
Metabolic disorders of biological oxidation enzymes
GPCR ligand binding
Drugs
Diseases
GWAS
Protein-protein Interactions
11 interactors:
CCL11
CCL13
CCL19
CCL2
CCL21
CCL25
CCL5
CCL7
CCL8
CDK2
CXCL13
Entrez ID
51554
HPRD ID
07298
Ensembl ID
ENSG00000129048
Uniprot IDs
Q9NPB9
PDB IDs
Enriched GO Terms of Interacting Partners
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Cell Chemotaxis
Leukocyte Chemotaxis
Leukocyte Migration
Inflammatory Response
Cellular Calcium Ion Homeostasis
Calcium Ion Homeostasis
Chemotaxis
Cellular Metal Ion Homeostasis
Cellular Cation Homeostasis
Regulation Of Leukocyte Migration
Cellular Ion Homeostasis
Metal Ion Homeostasis
Cell Migration
Cell Motility
Cellular Chemical Homeostasis
Ion Homeostasis
Positive Regulation Of Leukocyte Chemotaxis
Cellular Homeostasis
Positive Regulation Of Leukocyte Migration
Regulation Of Lymphocyte Migration
Locomotion
Eosinophil Chemotaxis
Immune Response
Eosinophil Migration
Defense Response
Positive Regulation Of Chemotaxis
Chemical Homeostasis
Positive Regulation Of Behavior
Movement Of Cell Or Subcellular Component
Regulation Of Chemotaxis
Regulation Of Cell Migration
Positive Regulation Of Cell Migration
Granulocyte Chemotaxis
Positive Regulation Of Cell Motility
Regulation Of Cell Motility
Positive Regulation Of Cellular Component Movement
Positive Regulation Of Locomotion
Regulation Of Locomotion
Response To External Stimulus
Regulation Of Cellular Component Movement
Regulation Of Behavior
Homeostatic Process
Immune System Process
Response To Stress
Regulation Of Granulocyte Chemotaxis
Regulation Of Cell-cell Adhesion
Positive Regulation Of Cell Adhesion
Dendritic Cell Chemotaxis
Monocyte Chemotaxis
Positive Regulation Of Cell-cell Adhesion
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