ACKR4

Description		atypical chemokine receptor 4
Image		No pdb structure
GO Annotations	Cellular Component	Endosome Early Endosome Plasma Membrane External Side Of Plasma Membrane Membrane Recycling Endosome
	Molecular Function	G Protein-coupled Receptor Activity Chemokine Receptor Activity Scavenger Receptor Activity Protein Binding C-C Chemokine Receptor Activity Chemokine Binding C-C Chemokine Binding
	Biological Process	Chemotaxis Immune Response Signal Transduction G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Vesicle-mediated Transport Calcium-mediated Signaling Cell Chemotaxis Chemokine-mediated Signaling Pathway
Pathways		Chemokine receptors bind chemokines
Drugs
Diseases
GWAS		Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Neonatal cytokine/chemokine levels (fetal genetic effect) ( 30134952) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		11 interacting genes: CCL11 CCL13 CCL19 CCL2 CCL21 CCL25 CCL5 CCL7 CCL8 CDK2 CXCL13
Entrez ID		51554
HPRD ID		07298
Ensembl ID		ENSG00000129048
Uniprot IDs		Q9NPB9
PDB IDs
Enriched GO Terms of Interacting Partners?		Eosinophil Migration Eosinophil Chemotaxis Chemokine Activity CCR Chemokine Receptor Binding Granulocyte Chemotaxis Chemokine-mediated Signaling Pathway Granulocyte Migration Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Myeloid Leukocyte Migration Leukocyte Chemotaxis Antimicrobial Humoral Response Cell Chemotaxis Cytokine Activity Leukocyte Migration Humoral Immune Response Chemotaxis Locomotion Cytokine-mediated Signaling Pathway Inflammatory Response Positive Regulation Of Cell Migration Positive Regulation Of Cell Motility Positive Regulation Of Locomotion Regulation Of Leukocyte Migration Defense Response To Symbiont Defense Response To Other Organism Killing Of Cells Of Another Organism G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Leukocyte Migration Cell Migration Regulation Of Lymphocyte Chemotaxis Regulation Of Cell Migration Cell Killing Regulation Of Cell Motility Cell Motility Regulation Of Locomotion Positive Regulation Of Leukocyte Chemotaxis Response To Other Organism Chemokine Receptor Binding Mononuclear Cell Migration Immune Response Response To External Biotic Stimulus Defense Response Positive Regulation Of Chemotaxis CCR10 Chemokine Receptor Binding Extracellular Space Positive Regulation Of Lymphocyte Chemotaxis Regulation Of Lymphocyte Migration Intracellular Calcium Ion Homeostasis Regulation Of Chemotaxis Calcium Ion Homeostasis
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