DMRTB1 and ZC3H10

Number of citations of the paper that reports this interaction (PubMedID 34133714)
84

Data Source:
BioGRID (two hybrid)

		DMRTB1	ZC3H10
Description		DMRT like family B with proline rich C-terminal 1	zinc finger CCCH-type containing 10
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus	Nucleus
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Sequence-specific DNA Binding Metal Ion Binding	RNA Binding Protein Binding Zinc Ion Binding MiRNA Binding Metal Ion Binding
	Biological Process	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Sex Differentiation	Post-transcriptional Regulation Of Gene Expression Regulation Of RNA Splicing Negative Regulation Of MiRNA Processing
Pathways
Drugs
Diseases
GWAS		Cerebrospinal fluid AB1-42 levels ( 28247064) Response to statin therapy ( 20339536)	Allergic disease (asthma, hay fever or eczema) ( 29785011) Anorexia nervosa ( 28494655) Asthma ( 31619474) Asthma or allergic disease (pleiotropy) ( 29785011)
Interacting Genes		90 interacting genes: ALG13 ANKHD1 BAG4 BCAS2 C1orf94 CCND3 CDKN2D CPEB2 CPSF7 CTBP1 CTBP2 EWSR1 EXOSC1 EXOSC5 EXOSC7 EYA2 FXR2 HNRNPUL1 IL16 INCA1 KAT5 KIF21B KRT81 KRTAP19-5 KRTAP19-6 KRTAP21-2 KRTAP8-1 LARP4B LENG8 MAZ MBNL1 MRPL44 MSI2 MTPAP NCKIPSD NEDD9 NIF3L1 NIP7 NXF1 PARD6G PATL1 PEF1 PKP2 PPIL3 PRMT2 PRPF39 PRPF6 PRR3 PRRC2B QKI RAMAC RBFOX1 RBFOX2 RBM14 RBM22 RBM42 RBM7 RBPMS RPA2 RPS28 SECISBP2 SF1 SF3B4 SFPQ SH3RF1 SLAIN1 SLIRP SNRPA SNRPB SNRPC SNRPN SNW1 SORBS3 SRSF2 TENT5A TEX10 TLE5 TNRC6A TOX TRNAU1AP TSG101 TXNL4A UBL5 UNKL VASP WBP4 YTHDF1 YTHDF3 ZC3H10 ZMAT5	52 interacting genes: ACTMAP ALG13 AOC1 APPBP2 ARID5A ATXN1 BOLL C10orf55 CRX DAB1 DAZAP2 DMRTB1 ESRP1 FAM168B FOSB FOXH1 HIVEP1 INTS11 KLHDC7B KRTAP19-1 KRTAP6-1 KRTAP6-2 KRTAP8-1 LASP1 MIR143 MSX2 NCS1 NFYA OTX2 OXER1 PIAS2 PICALM PLA2G10 POU2F1 PRR20A PRR20B PRR20C PRR20D PRR20E QKI RBFOX2 RBM38 RBPMS RBPMS2 RNF4 SNRPA SPMIP9 STAM2 TENT5A TENT5B UBE2I ZNF34
Entrez ID		63948	84872
HPRD ID		16828	07860
Ensembl ID		ENSG00000143006	ENSG00000135482
Uniprot IDs		I6L9A0 Q96MA1	Q96K80
PDB IDs
Enriched GO Terms of Interacting Partners?		RNA Binding MRNA Processing RNA Processing MRNA Metabolic Process RNA Splicing Nucleic Acid Binding MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Metabolic Process Nucleic Acid Metabolic Process Spliceosomal Complex Regulation Of MRNA Metabolic Process Nucleus MRNA Binding Nucleobase-containing Compound Metabolic Process Regulation Of RNA Splicing Nucleoplasm Cytoplasmic Stress Granule Regulation Of MRNA Splicing, Via Spliceosome Protein Binding Regulation Of MRNA Processing U1 SnRNP Macromolecule Metabolic Process U4/U6 X U5 Tri-snRNP Complex Catalytic Step 2 Spliceosome Negative Regulation Of Macromolecule Metabolic Process U2-type Prespliceosome Regulation Of Alternative MRNA Splicing, Via Spliceosome Regulation Of Macromolecule Metabolic Process U5 SnRNP Spliceosomal Complex Assembly Negative Regulation Of Metabolic Process U2-type Precatalytic Spliceosome Negative Regulation Of RNA Metabolic Process Protein-RNA Complex Assembly Transcription Corepressor Activity Negative Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Membraneless Organelle Assembly Nucleolar Exosome (RNase Complex) Negative Regulation Of MRNA Metabolic Process U2-type Catalytic Step 2 Spliceosome Intermediate Filament Negative Regulation Of Biosynthetic Process Regulation Of Gene Expression Ribonucleoprotein Complex Negative Regulation Of Nucleobase-containing Compound Metabolic Process Cytoplasm Regulation Of Metabolic Process Cytoplasmic Exosome (RNase Complex)	Regulation Of RNA Metabolic Process Regulation Of MRNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process MRNA Stabilization Negative Regulation Of RNA Metabolic Process Negative Regulation Of MRNA Catabolic Process RNA Stabilization Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of RNA Catabolic Process Regulation Of Gene Expression Negative Regulation Of MRNA Metabolic Process Regulation Of RNA Splicing Regulation Of Macromolecule Biosynthetic Process Regulation Of MRNA Stability Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process MRNA 3'-UTR Binding Regulation Of RNA Stability Regulation Of Primary Metabolic Process MRNA Binding Cytoplasmic Stress Granule Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Macromolecule Metabolic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Biosynthetic Process DNA Binding Negative Regulation Of Macromolecule Metabolic Process Nucleic Acid Binding Regulation Of MRNA Splicing, Via Spliceosome Poly(A) RNA Polymerase Activity Positive Regulation Of Biosynthetic Process Regulation Of MRNA Processing Positive Regulation Of RNA Metabolic Process Negative Regulation Of Metabolic Process Negative Regulation Of Androgen Receptor Signaling Pathway Regulation Of Alternative MRNA Splicing, Via Spliceosome Positive Regulation Of Macromolecule Metabolic Process DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Negative Regulation Of DNA-templated Transcription Intermediate Filament Regulation Of Metabolic Process Negative Regulation Of RNA Biosynthetic Process RNA Binding Transcription Factor Binding SUMO Transferase Activity 3'-UTR-mediated MRNA Stabilization
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