DMRTB1 and PRR3

Number of citations of the paper that reports this interaction (PubMedID 34133714)
84

Data Source:
BioGRID (two hybrid)

		DMRTB1	PRR3
Description		DMRT like family B with proline rich C-terminal 1	proline rich 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Sequence-specific DNA Binding Metal Ion Binding	RNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Sex Differentiation
Pathways
Drugs
Diseases
GWAS		Cerebrospinal fluid AB1-42 levels ( 28247064) Response to statin therapy ( 20339536)	Autism spectrum disorder or schizophrenia ( 28540026) Itch intensity from mosquito bite ( 28199695) Neuroticism ( 29255261)
Interacting Genes		90 interacting genes: ALG13 ANKHD1 BAG4 BCAS2 C1orf94 CCND3 CDKN2D CPEB2 CPSF7 CTBP1 CTBP2 EWSR1 EXOSC1 EXOSC5 EXOSC7 EYA2 FXR2 HNRNPUL1 IL16 INCA1 KAT5 KIF21B KRT81 KRTAP19-5 KRTAP19-6 KRTAP21-2 KRTAP8-1 LARP4B LENG8 MAZ MBNL1 MRPL44 MSI2 MTPAP NCKIPSD NEDD9 NIF3L1 NIP7 NXF1 PARD6G PATL1 PEF1 PKP2 PPIL3 PRMT2 PRPF39 PRPF6 PRR3 PRRC2B QKI RAMAC RBFOX1 RBFOX2 RBM14 RBM22 RBM42 RBM7 RBPMS RPA2 RPS28 SECISBP2 SF1 SF3B4 SFPQ SH3RF1 SLAIN1 SLIRP SNRPA SNRPB SNRPC SNRPN SNW1 SORBS3 SRSF2 TENT5A TEX10 TLE5 TNRC6A TOX TRNAU1AP TSG101 TXNL4A UBL5 UNKL VASP WBP4 YTHDF1 YTHDF3 ZC3H10 ZMAT5	25 interacting genes: APOBEC3C ASF1A BCL2L2-PABPN1 CCDC57 CLP1 DMRTB1 EXOSC8 HNRNPA0 KHDRBS2 KHDRBS3 KLF1 KRT31 KRTAP6-2 KRTAP6-3 MYPOP NXF1 PSMA3 RAMAC RBM3 RBMX RBMY1A1 RBMY1F RBMY1J SNRPA TLE5
Entrez ID		63948	80742
HPRD ID		16828	17915
Ensembl ID		ENSG00000143006	ENSG00000204576
Uniprot IDs		I6L9A0 Q96MA1	B3KQA4 P79522 Q96QB9
PDB IDs
Enriched GO Terms of Interacting Partners?		RNA Binding MRNA Processing RNA Processing MRNA Metabolic Process RNA Splicing Nucleic Acid Binding MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Metabolic Process Nucleic Acid Metabolic Process Spliceosomal Complex Regulation Of MRNA Metabolic Process Nucleus MRNA Binding Nucleobase-containing Compound Metabolic Process Regulation Of RNA Splicing Nucleoplasm Cytoplasmic Stress Granule Regulation Of MRNA Splicing, Via Spliceosome Protein Binding Regulation Of MRNA Processing U1 SnRNP Macromolecule Metabolic Process U4/U6 X U5 Tri-snRNP Complex Catalytic Step 2 Spliceosome Negative Regulation Of Macromolecule Metabolic Process U2-type Prespliceosome Regulation Of Alternative MRNA Splicing, Via Spliceosome Regulation Of Macromolecule Metabolic Process U5 SnRNP Spliceosomal Complex Assembly Negative Regulation Of Metabolic Process U2-type Precatalytic Spliceosome Negative Regulation Of RNA Metabolic Process Protein-RNA Complex Assembly Transcription Corepressor Activity Negative Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Membraneless Organelle Assembly Nucleolar Exosome (RNase Complex) Negative Regulation Of MRNA Metabolic Process U2-type Catalytic Step 2 Spliceosome Intermediate Filament Negative Regulation Of Biosynthetic Process Regulation Of Gene Expression Ribonucleoprotein Complex Negative Regulation Of Nucleobase-containing Compound Metabolic Process Cytoplasm Regulation Of Metabolic Process Cytoplasmic Exosome (RNase Complex)	Regulation Of MRNA Splicing, Via Spliceosome MRNA Processing MRNA Metabolic Process Positive Regulation Of MRNA Splicing, Via Spliceosome Regulation Of MRNA Processing RNA Processing Nucleic Acid Binding Positive Regulation Of RNA Splicing Regulation Of RNA Splicing Regulation Of MRNA Metabolic Process RNA Binding RNA Metabolic Process Spliceosomal Complex Nucleic Acid Metabolic Process MRNA Binding Positive Regulation Of MRNA Metabolic Process Regulation Of Alternative MRNA Splicing, Via Spliceosome RNA Splicing Nucleus Nucleobase-containing Compound Metabolic Process Nucleoplasm Regulation Of RNA Metabolic Process Identical Protein Binding Regulation Of Gene Expression MRNA 3'-UTR AU-rich Region Binding Regulation Of Macromolecule Biosynthetic Process Regulation Of Nucleobase-containing Compound Metabolic Process Macromolecule Metabolic Process Positive Regulation Of Gene Expression Intermediate Filament ATP-dependent Polyribonucleotide 5'-hydroxyl-kinase Activity Polynucleotide 5'-hydroxyl-kinase Activity ATP-dependent Polynucleotide 5'-hydroxyl-kinase Activity MRNA Capping Enzyme Complex MRNA Cap Methyltransferase RNMT:RAMAC Complex RNA 5'-cap (guanine-N7)-methylation Regulation Of Macromolecule Metabolic Process Global Gene Silencing By MRNA Cleavage U5 SnRNA 3'-end Processing U1 SnRNA 3'-end Processing Supraspliceosomal Complex Keratinization
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