EIF3L and POLR1B

Number of citations of the paper that reports this interaction (PMID 11592397)
4

Data Source:
HPRD (in vitro)

		EIF3L	POLR1B
Gene Name		eukaryotic translation initiation factor 3, subunit L	polymerase (RNA) I polypeptide B, 128kDa
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Eukaryotic Translation Initiation Factor 3 Complex Membrane Eukaryotic 43S Preinitiation Complex Eukaryotic 48S Preinitiation Complex	Nucleoplasm Nucleolus DNA-directed RNA Polymerase I Complex Cytoplasm
	Molecular Function	Translation Initiation Factor Activity Protein Binding Poly(A) RNA Binding	RNA Polymerase I Activity DNA Binding Protein Binding Ribonucleoside Binding Metal Ion Binding
	Biological Process	Formation Of Translation Preinitiation Complex Translational Initiation Regulation Of Translational Initiation	Transcription From RNA Polymerase I Promoter Transcription Initiation From RNA Polymerase I Promoter Transcription Elongation From RNA Polymerase I Promoter Termination Of RNA Polymerase I Transcription Embryo Implantation RRNA Transcription Gene Expression Nucleologenesis Regulation Of Gene Expression, Epigenetic Negative Regulation Of Gene Expression, Epigenetic
Pathways			NoRC negatively regulates rRNA expression RNA Polymerase I Chain Elongation RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription RNA Polymerase I Transcription Initiation RNA Polymerase I Transcription RNA Polymerase I Transcription Termination RNA Polymerase I Promoter Escape RNA Polymerase I Promoter Clearance Epigenetic regulation of gene expression Negative epigenetic regulation of rRNA expression
Drugs
Diseases
GWAS
Protein-Protein Interactions		9 interactors: DNM2 EIF3D EIF3E EIF3K POLR1B RGS2 RRN3 SMAD2 XRN2	14 interactors: AKT2 CCND1 EIF3L ESR1 GIT2 HDAC6 LDB1 LZTR1 MED20 NFKBIB POLR1E RPL37 RRN3 ZNF207
Entrez ID		51386	84172
HPRD ID		10932	06852
Ensembl ID		ENSG00000100129	ENSG00000125630
Uniprot IDs		B0QY90 Q9Y262	Q9H9Y6
PDB IDs
Enriched GO Terms of Interacting Partners?		Formation Of Translation Preinitiation Complex Posttranscriptional Regulation Of Gene Expression Regulation Of Gene Expression Nucleolus Organization Regulation Of Translational Initiation Regulation Of Translation Ribonucleoprotein Complex Biogenesis Ribonucleoprotein Complex Assembly Regulation Of Metabolic Process Gene Expression Transcription Initiation From RNA Polymerase I Promoter Cellular Macromolecule Biosynthetic Process Cellular Macromolecular Complex Assembly Macromolecule Biosynthetic Process Translational Initiation Transcription From RNA Polymerase I Promoter DNA-templated Transcription, Initiation DNA-templated Transcription, Termination Biosynthetic Process Nucleologenesis Negative Regulation Of Membrane Tubulation Positive Regulation Of Nodal Signaling Pathway Involved In Determination Of Lateral Mesoderm Left/right Asymmetry Formation Of Cytoplasmic Translation Initiation Complex Nucleus Organization Regulation Of Nodal Signaling Pathway Involved In Determination Of Lateral Mesoderm Left/right Asymmetry Zygotic Specification Of Dorsal/ventral Axis Translation RNA Catabolic Process Positive Regulation Of Mesoderm Development Primary MiRNA Processing Regulation Of Adrenergic Receptor Signaling Pathway Regulation Of Nodal Signaling Pathway Common-partner SMAD Protein Phosphorylation Positive Regulation Of Cardiac Muscle Contraction Regulation Of Gene Expression, Epigenetic Cytoplasmic Translational Initiation Negative Regulation Of CAMP-mediated Signaling Positive Regulation Of Activin Receptor Signaling Pathway Cytoplasm Organization Negative Regulation Of Phospholipase Activity RNA Metabolic Process Relaxation Of Vascular Smooth Muscle Cellular Component Assembly Relaxation Of Smooth Muscle Negative Regulation Of Cardiac Muscle Hypertrophy Regulation Of Cellular Component Organization Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Striated Muscle Contraction Negative Regulation Of Muscle Hypertrophy SMAD Protein Complex Assembly	Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Gene Expression RNA Biosynthetic Process Gene Expression Regulation Of Metabolic Process Biosynthetic Process DNA-templated Transcription, Initiation Transcription, DNA-templated RNA Metabolic Process Mammary Gland Epithelium Development Mammary Gland Epithelial Cell Proliferation Transcription Initiation From RNA Polymerase I Promoter Mammary Gland Development Transcription From RNA Polymerase I Promoter Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Chromosome Organization Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Mammary Gland Lobule Development Mammary Gland Alveolus Development Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Chromatin Organization Histone H3-K4 Acetylation Positive Regulation Of Hydrogen Peroxide-mediated Programmed Cell Death Transcription-dependent Tethering Of RNA Polymerase II Gene DNA At Nuclear Periphery Hsp90 Deacetylation Negative Regulation Of Gene Expression Regulation Of Protein Metabolic Process Regulation Of Oxidoreductase Activity Positive Regulation Of Type I Interferon Production Nitrogen Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Chaperone-mediated Protein Complex Assembly RNA Polymerase I Transcriptional Preinitiation Complex Assembly At The Promoter For The Nuclear Large RRNA Transcript Positive Regulation Of Hemoglobin Biosynthetic Process Polyubiquitinated Misfolded Protein Transport Epithelial Cell Proliferation Regulation Of Cell Cycle Arrest Positive Regulation Of Metabolic Process Re-entry Into Mitotic Cell Cycle Prostate Epithelial Cord Elongation Transcription Of Nuclear Large RRNA Transcript From RNA Polymerase I Promoter Cellular Response To Topologically Incorrect Protein Regulation Of Type I Interferon Production
Tagcloud ?		biologically chromatography complex complexes composed consisting coupled devoid efficient encoding eukaryotic feasible hela incubation initiation native nonessential plasmids prepare programmed rapid reconstitute reconstituted reconstitution subunits system tag translation
Tagcloud (Difference) ?		biologically chromatography complex complexes composed consisting coupled devoid efficient encoding eukaryotic feasible hela incubation initiation native nonessential plasmids prepare programmed rapid reconstitute reconstituted reconstitution subunits system tag translation
Tagcloud (Intersection) ?