EIF3L

Gene Name		eukaryotic translation initiation factor 3, subunit L
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Eukaryotic Translation Initiation Factor 3 Complex Membrane Eukaryotic 43S Preinitiation Complex Eukaryotic 48S Preinitiation Complex
	Molecular Function	Translation Initiation Factor Activity Protein Binding Poly(A) RNA Binding
	Biological Process	Formation Of Translation Preinitiation Complex Translational Initiation Regulation Of Translational Initiation
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		9 interactors: DNM2 EIF3D EIF3E EIF3K POLR1B RGS2 RRN3 SMAD2 XRN2
Entrez ID		51386
HPRD ID		10932
Ensembl ID		ENSG00000100129
Uniprot IDs		B0QY90 Q9Y262
PDB IDs
Enriched GO Terms of Interacting Partners?		Formation Of Translation Preinitiation Complex Posttranscriptional Regulation Of Gene Expression Regulation Of Gene Expression Nucleolus Organization Regulation Of Translational Initiation Regulation Of Translation Ribonucleoprotein Complex Biogenesis Ribonucleoprotein Complex Assembly Regulation Of Metabolic Process Gene Expression Transcription Initiation From RNA Polymerase I Promoter Cellular Macromolecule Biosynthetic Process Cellular Macromolecular Complex Assembly Macromolecule Biosynthetic Process Translational Initiation Transcription From RNA Polymerase I Promoter DNA-templated Transcription, Initiation DNA-templated Transcription, Termination Biosynthetic Process Nucleologenesis Negative Regulation Of Membrane Tubulation Positive Regulation Of Nodal Signaling Pathway Involved In Determination Of Lateral Mesoderm Left/right Asymmetry Formation Of Cytoplasmic Translation Initiation Complex Nucleus Organization Regulation Of Nodal Signaling Pathway Involved In Determination Of Lateral Mesoderm Left/right Asymmetry Zygotic Specification Of Dorsal/ventral Axis Translation RNA Catabolic Process Positive Regulation Of Mesoderm Development Primary MiRNA Processing Regulation Of Adrenergic Receptor Signaling Pathway Regulation Of Nodal Signaling Pathway Common-partner SMAD Protein Phosphorylation Positive Regulation Of Cardiac Muscle Contraction Regulation Of Gene Expression, Epigenetic Cytoplasmic Translational Initiation Negative Regulation Of CAMP-mediated Signaling Positive Regulation Of Activin Receptor Signaling Pathway Cytoplasm Organization Negative Regulation Of Phospholipase Activity RNA Metabolic Process Relaxation Of Vascular Smooth Muscle Cellular Component Assembly Relaxation Of Smooth Muscle Negative Regulation Of Cardiac Muscle Hypertrophy Regulation Of Cellular Component Organization Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Striated Muscle Contraction Negative Regulation Of Muscle Hypertrophy SMAD Protein Complex Assembly
Tagcloud ?		biologically chromatography complex complexes composed consisting coupled devoid efficient encoding eukaryotic feasible hela incubation initiation native nonessential plasmids prepare programmed rapid reconstitute reconstituted reconstitution subunits system tag translation