WAC and KRT15

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid, two hybrid)
HPRD (two hybrid)

		WAC	KRT15
Gene Name		WW domain containing adaptor with coiled-coil	keratin 15, type I
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex Nuclear Speck	Nucleus Intermediate Filament Extracellular Vesicular Exosome
	Molecular Function	RNA Polymerase II Core Binding Chromatin Binding Protein Binding	Structural Constituent Of Cytoskeleton Protein Binding Scaffold Protein Binding
	Biological Process	Transcription, DNA-templated Cellular Response To DNA Damage Stimulus Histone Monoubiquitination Positive Regulation Of Macroautophagy Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process G1 DNA Damage Checkpoint Positive Regulation Of Transcription, DNA-templated Histone H2B Conserved C-terminal Lysine Ubiquitination	Epidermis Development
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		22 interactors: AKAP9 APP CRKL CTD DYDC1 KLC3 KRT15 LNX1 MTUS2 NDE1 NFE2L2 POLR2A RNF20 RNF40 SYTL5 TRAF1 TRAF3IP1 TRAF3IP3 UBQLN4 VCP VCPIP1 ZDHHC17	115 interactors: ABI2 ABI3 ABLIM1 AES ALS2CR11 AMOT AMOTL2 ANKRD36BP1 APC ARC ARFIP2 ATP5O BEX2 C10orf10 C1orf216 CALCOCO1 CCDC101 CCDC120 CCDC185 CCDC67 CCDC87 CCHCR1 CCNB1IP1 CCNC CEP57 COX5B CREB5 CYTH4 DGCR6L EPC1 EXOC8 FAM107A FAM110A GFAP GLYCTK HAUS1 HGS HMG20B HOXB6 IKBIP KANSL1 KIAA0408 KIAA1217 KIFC3 KLC3 KLC4 KRT18 KRT19 KRT20 KRT4 KRT5 KRT6A KRT6B KRT6C KRT71 KRT73 KRT77 KRT79 KRT8 KRT80 KRT81 KRT86 LDOC1 LMO2 LMO4 LNX1 MAD2L1BP MBD3 MCM10 MORN3 MOS NEFL NIF3L1 NOC4L NUDT18 NUP54 OIP5 PCM1 PIK3R2 PKN1 PPP1R18 PRPF31 PRPH PSMA1 PSMB1 PSMC5 RAD51D RCOR3 RHPN1 RIBC1 RIBC2 SIRPA SMARCD1 SMARCE1 SPG21 SSX2IP TCHP TEKT4 TIMM8A TMSB4X TRIM42 TSG101 TUBGCP4 TXLNA TXLNB TXNDC11 USHBP1 USP2 WAC ZC2HC1C ZFYVE26 ZGPAT ZNF417 ZNF576 ZNF638
Entrez ID		51322	3866
HPRD ID		18291	01009
Ensembl ID		ENSG00000095787	ENSG00000171346
Uniprot IDs		Q9BTA9	A8MT21 B3KVF5 P19012
PDB IDs
Enriched GO Terms of Interacting Partners?		Microtubule-based Transport Protein Ubiquitination Cytoskeleton-dependent Intracellular Transport Protein Modification By Small Protein Conjugation Histone H2B Ubiquitination Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein Catabolic Process Microtubule-based Movement Histone Monoubiquitination Cellular Component Assembly Histone Ubiquitination Cellular Macromolecule Catabolic Process Protein Monoubiquitination Intracellular Transport Proteolysis Axon Cargo Transport Positive Regulation Of Lys63-specific Deubiquitinase Activity Positive Regulation Of Protein K63-linked Deubiquitination Positive Regulation Of Cellular Protein Metabolic Process Cellular Protein Modification Process Synaptic Growth At Neuromuscular Junction Endoplasmic Reticulum Membrane Fusion Transcription, RNA-templated Positive Regulation Of Protein Metabolic Process Positive Regulation Of Cellular Metabolic Process Endoplasmic Reticulum Unfolded Protein Response Microtubule-based Process Regulation Of Cellular Protein Metabolic Process Collateral Sprouting In Absence Of Injury Cellular Response To Unfolded Protein Establishment Of Localization In Cell ER-nucleus Signaling Pathway Proteasomal Ubiquitin-independent Protein Catabolic Process Golgi Reassembly Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Oxidative Stress Cellular Response To Topologically Incorrect Protein Regulation Of Embryonic Development G2/M Transition Of Mitotic Cell Cycle Collateral Sprouting Axon Midline Choice Point Recognition Retrograde Protein Transport, ER To Cytosol Regulation Of Protein Metabolic Process Positive Regulation Of Protein Modification Process Response To Unfolded Protein Regulation Of Protein Deubiquitination Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process	Organelle Organization Cytoskeleton Organization Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Cell Cycle Cell Cycle Process Intermediate Filament Organization Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Mitotic Cell Cycle Process Cellular Component Assembly Microtubule-based Process Mitotic Cell Cycle Chromosome Organization Microtubule Cytoskeleton Organization Chromatin Organization Chromatin Modification Cellular Process Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process G1 DNA Damage Checkpoint Intraciliary Transport Involved In Cilium Morphogenesis Anatomical Structure Development RNA Biosynthetic Process Negative Regulation Of Canonical Wnt Signaling Pathway Cell Cycle Checkpoint Transcription, DNA-templated Mitotic Cell Cycle Checkpoint Gene Expression Movement Of Cell Or Subcellular Component Chromatin Remodeling Regulation Of Protein Catabolic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Negative Regulation Of Wnt Signaling Pathway RNA Metabolic Process Developmental Process Histone Acetylation Internal Peptidyl-lysine Acetylation Viral Process Peptidyl-lysine Acetylation Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Positive Regulation Of Canonical Wnt Signaling Pathway Internal Protein Amino Acid Acetylation DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Signal Transduction Involved In Mitotic G1 DNA Damage Checkpoint Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition Negative Regulation Of Cell Cycle Nucleobase-containing Compound Metabolic Process
Tagcloud ?		bd ccrd composite cooking defatted equation fitted flour gruel gsl ingredient moisture noodle noodles polynomial proximate quadratic rotatable salted sc soy swelling tapioca ve wheat wur x1 x2 x3	17beta 3a additive canonical chemotherapeutic chosen combinatorial communications cooperation cooperative doxorubicin epha2 ers flt1 fuorouracil gdnf inpp5d mcf7 microarrays noncanonical notch1 nutlin responsiveness searches silenced sox9 tlr5 transcriptome vegfr
Tagcloud (Difference) ?		bd ccrd composite cooking defatted equation fitted flour gruel gsl ingredient moisture noodle noodles polynomial proximate quadratic rotatable salted sc soy swelling tapioca ve wheat wur x1 x2 x3	17beta 3a additive canonical chemotherapeutic chosen combinatorial communications cooperation cooperative doxorubicin epha2 ers flt1 fuorouracil gdnf inpp5d mcf7 microarrays noncanonical notch1 nutlin responsiveness searches silenced sox9 tlr5 transcriptome vegfr
Tagcloud (Intersection) ?