KRT15 and KRT76

Number of citations of the paper that reports this interaction (PubMedID 36949045)
82

Data Source:
BioGRID (two hybrid, cross-linking study)

		KRT15	KRT76
Description		keratin 15	keratin 76
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol Cytoskeleton Intermediate Filament Keratin Filament Extracellular Exosome	Nucleus Cytosol Intermediate Filament Keratin Filament Extracellular Exosome
	Molecular Function	Structural Molecule Activity Structural Constituent Of Cytoskeleton Protein Binding Structural Constituent Of Skin Epidermis Scaffold Protein Binding	Protein Binding Structural Constituent Of Skin Epidermis
	Biological Process	Morphogenesis Of An Epithelium Epidermis Development Epithelial Cell Differentiation Intermediate Filament Organization	Cytoskeleton Organization Epidermis Development Keratinization Pigmentation Intermediate Filament Organization Sebaceous Gland Development
Pathways		Keratinization Formation of the cornified envelope Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin	Keratinization Formation of the cornified envelope
Drugs
Diseases
GWAS
Interacting Genes		144 interacting genes: ABI2 ABI3 ABLIM1 AMOT AMOTL2 ANKRD36BP1 APC ARC ARFIP2 ATP5PO BEX2 C1orf216 CALCOCO1 CARD9 CATSPERT CCDC120 CCDC185 CCDC187 CCDC87 CCHCR1 CCNB1IP1 CCNC CDK18 CEP57 COX5B CREB5 CYTH4 DEPP1 DES DEUP1 DGCR6L DRC4 DTNB EFHC1 ENKD1 EPC1 EXOC8 FAM107A FAM110A GFAP GLYCTK HAPLN2 HAUS1 HGS HMG20B HOXB6 IKBIP KANSL1 KDM1A KIAA0408 KIAA1217 KIFC3 KLC3 KLC4 KRT1 KRT18 KRT19 KRT20 KRT3 KRT5 KRT6A KRT6B KRT6C KRT71 KRT72 KRT73 KRT74 KRT76 KRT77 KRT78 KRT79 KRT8 KRT80 KRT81 KRT82 KRT83 KRT85 KRT86 LDOC1 LMO2 LMO4 LNX1 MAD2L1BP MBD3 MCM10 MORN3 MOS NEFL NIF3L1 NOC4L NUDT18 NUP54 OIP5 PCM1 PIK3R2 PKN1 PPP1R18 PRPF31 PRPH PSMA1 PSMB1 PSMC5 RAD51D RAMAC RCOR3 RHPN1 RIBC1 RIBC2 RNF6 RPP25 RSPH14 SGF29 SIRPA SMARCB1 SMARCD1 SMARCE1 SNAPIN SPG21 SSX2IP TBC1D21 TCHP TEKT4 TELO2 TIMM8A TLE5 TMSB4X TRIM42 TRIML2 TSG101 TTC23 TUBGCP4 TXLNA TXLNB TXNDC11 USHBP1 USP2 WAC ZC2HC1C ZFYVE26 ZGPAT ZNF417 ZNF576 ZNF638 ZNF688	47 interacting genes: AIRIM C1orf216 CAMK2A CCDC57 CDC37 CFAP206 DPPA3 EXOC8 FOXR2 FRS3 HGS IPO11 IQUB KIFC3 KRT13 KRT15 KRT16 KRT19 KRT25 KRT26 KRT27 KRT28 KRT31 KRT32 KRT33B KRT35 KRT36 KRT37 KRT38 KRT39 KRT40 KRT75 KRT86 LCA5L LMO4 MID2 MTUS2 NFKBID POLR1C RSPH14 TNS2 TRIM23 TRIM27 TRIM54 TSGA10 WASHC1 ZNF655
Entrez ID		3866	51350
HPRD ID		01009	17123
Ensembl ID		ENSG00000171346	ENSG00000185069
Uniprot IDs		B3KVF5 P19012	Q01546
PDB IDs
Enriched GO Terms of Interacting Partners?		Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Structural Constituent Of Skin Epidermis Keratin Filament Intermediate Filament Keratinization Cytoskeleton Organization Supramolecular Fiber Organization Organelle Organization Protein Binding Cytoskeleton Structural Constituent Of Cytoskeleton Microtubule-based Process Intermediate Filament Cytoskeleton Microtubule-based Movement Centrosome Axonemal A Tubule Inner Sheath Flagellated Sperm Motility Sperm Motility Intermediate Filament Polymerization Or Depolymerization Cilium-dependent Cell Motility Cilium Movement Involved In Cell Motility Brahma Complex NpBAF Complex Establishment Of Cell Polarity Involved In Ameboidal Cell Migration RSC-type Complex Regulation Of Sister Chromatid Segregation NBAF Complex Cell Projection Microtubule Cytoskeleton Organization Motile Cilium Nucleosome Disassembly Microtubule Cilium Movement Sperm Mitochondrial Sheath Assembly Protein-DNA Complex Disassembly	Structural Constituent Of Skin Epidermis Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Intermediate Filament Structural Molecule Activity Supramolecular Fiber Organization Morphogenesis Of An Epithelium Cytoskeleton Epithelial Cell Differentiation Tissue Morphogenesis Cytoskeleton Organization Organelle Organization Extracellular Exosome Anatomical Structure Morphogenesis Cell Differentiation Radial Spoke Hair Cycle Protein Binding Cellular Developmental Process Cytosol Hair Follicle Morphogenesis Phosphatidylinositol 3-kinase Inhibitor Activity Structural Constituent Of Cytoskeleton Regulation Of Autophagy Developmental Process Epidermis Development Negative Regulation Of Viral Transcription Exocyst Keratinization Suppression Of Viral Release By Host Arp2/3 Complex-mediated Actin Nucleation Hair Cycle Process Positive Regulation Of Autophagy Regulation Of Viral Transcription Actin Nucleation
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