KRT15 and KRT18

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		KRT15	KRT18
Gene Name		keratin 15, type I	keratin 18, type I
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Intermediate Filament Extracellular Vesicular Exosome	Nucleolus Cytoplasm Microtubule Organizing Center Intermediate Filament Centriolar Satellite Keratin Filament Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome Cell Periphery
	Molecular Function	Structural Constituent Of Cytoskeleton Protein Binding Scaffold Protein Binding	Structural Molecule Activity Protein Binding Poly(A) RNA Binding Scaffold Protein Binding
	Biological Process	Epidermis Development	Cell Cycle Anatomical Structure Morphogenesis Viral Process Tumor Necrosis Factor-mediated Signaling Pathway Golgi To Plasma Membrane CFTR Protein Transport Negative Regulation Of Apoptotic Process Intermediate Filament Cytoskeleton Organization Extrinsic Apoptotic Signaling Pathway Hepatocyte Apoptotic Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		115 interactors: ABI2 ABI3 ABLIM1 AES ALS2CR11 AMOT AMOTL2 ANKRD36BP1 APC ARC ARFIP2 ATP5O BEX2 C10orf10 C1orf216 CALCOCO1 CCDC101 CCDC120 CCDC185 CCDC67 CCDC87 CCHCR1 CCNB1IP1 CCNC CEP57 COX5B CREB5 CYTH4 DGCR6L EPC1 EXOC8 FAM107A FAM110A GFAP GLYCTK HAUS1 HGS HMG20B HOXB6 IKBIP KANSL1 KIAA0408 KIAA1217 KIFC3 KLC3 KLC4 KRT18 KRT19 KRT20 KRT4 KRT5 KRT6A KRT6B KRT6C KRT71 KRT73 KRT77 KRT79 KRT8 KRT80 KRT81 KRT86 LDOC1 LMO2 LMO4 LNX1 MAD2L1BP MBD3 MCM10 MORN3 MOS NEFL NIF3L1 NOC4L NUDT18 NUP54 OIP5 PCM1 PIK3R2 PKN1 PPP1R18 PRPF31 PRPH PSMA1 PSMB1 PSMC5 RAD51D RCOR3 RHPN1 RIBC1 RIBC2 SIRPA SMARCD1 SMARCE1 SPG21 SSX2IP TCHP TEKT4 TIMM8A TMSB4X TRIM42 TSG101 TUBGCP4 TXLNA TXLNB TXNDC11 USHBP1 USP2 WAC ZC2HC1C ZFYVE26 ZGPAT ZNF417 ZNF576 ZNF638	73 interactors: BBS1 BBS2 BBS4 BBS7 CAMK2A CASP3 CASP6 CASP7 CASP8 CBL CCDC146 CCDC85B CCNI CDC5L CDK1 COL17A1 DEDD DNAJB6 EGFR EP300 EXOC8 FRAT1 GIT2 GOLGA2 GRN HAUS1 HGS HRAS HSPA1A HSPA4 HSPA5 IKBKG KPNA2 KRT15 KRT5 KRT72 KRT8 LDOC1 MAPK14 NME7 ORC5 PDE4DIP PIAS4 PKD1 PKP2 PKP3 PNN POT1 PRKCA PRKCE RAF1 RHPN2 RPS6KA3 SERPINE1 SHC1 SMARCD1 SUMO1 SVIL TCHP TNFRSF1B TRADD TUBG1 TUBGCP4 TXN2 TXNDC11 UPF2 USH2A YTHDC1 YWHAB YWHAE YWHAG YWHAH YWHAZ
Entrez ID		3866	3875
HPRD ID		01009	01020
Ensembl ID		ENSG00000171346	ENSG00000111057
Uniprot IDs		A8MT21 B3KVF5 P19012	P05783
PDB IDs
Enriched GO Terms of Interacting Partners?		Organelle Organization Cytoskeleton Organization Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Cell Cycle Cell Cycle Process Intermediate Filament Organization Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Mitotic Cell Cycle Process Cellular Component Assembly Microtubule-based Process Mitotic Cell Cycle Chromosome Organization Microtubule Cytoskeleton Organization Chromatin Organization Chromatin Modification Cellular Process Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process G1 DNA Damage Checkpoint Intraciliary Transport Involved In Cilium Morphogenesis Anatomical Structure Development RNA Biosynthetic Process Negative Regulation Of Canonical Wnt Signaling Pathway Cell Cycle Checkpoint Transcription, DNA-templated Mitotic Cell Cycle Checkpoint Gene Expression Movement Of Cell Or Subcellular Component Chromatin Remodeling Regulation Of Protein Catabolic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Negative Regulation Of Wnt Signaling Pathway RNA Metabolic Process Developmental Process Histone Acetylation Internal Peptidyl-lysine Acetylation Viral Process Peptidyl-lysine Acetylation Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Positive Regulation Of Canonical Wnt Signaling Pathway Internal Protein Amino Acid Acetylation DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Signal Transduction Involved In Mitotic G1 DNA Damage Checkpoint Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition Negative Regulation Of Cell Cycle Nucleobase-containing Compound Metabolic Process	Apoptotic Process Programmed Cell Death Cell Death Death Apoptotic Signaling Pathway Intrinsic Apoptotic Signaling Pathway Regulation Of Cell Death Regulation Of Protein Metabolic Process Cellular Response To Organic Substance Neurotrophin TRK Receptor Signaling Pathway Regulation Of Apoptotic Process Neurotrophin Signaling Pathway Regulation Of Cellular Protein Metabolic Process Response To Organic Substance Cellular Response To Growth Factor Stimulus Response To Growth Factor Cell Surface Receptor Signaling Pathway Epidermal Growth Factor Receptor Signaling Pathway Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway ERBB Signaling Pathway Cellular Component Assembly Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Cell Communication Positive Regulation Of Cellular Protein Metabolic Process Membrane Organization Signal Transduction Positive Regulation Of Signal Transduction Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Signaling Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Organelle Organization Innate Immune Response Fibroblast Growth Factor Receptor Signaling Pathway Regulation Of Signal Transduction Positive Regulation Of Protein Metabolic Process Positive Regulation Of Transport Anatomical Structure Development Mitotic Cell Cycle Regulation Of Cellular Component Organization Regulation Of Signaling Mitotic Cell Cycle Phase Transition Cellular Response To Fibroblast Growth Factor Stimulus Cell Cycle Phase Transition Enzyme Linked Receptor Protein Signaling Pathway Response To Fibroblast Growth Factor Developmental Process Defense Response Regulation Of Proteolysis Cellular Protein Localization Cellular Response To Stimulus
Tagcloud ?		17beta 3a additive canonical chemotherapeutic chosen combinatorial communications cooperation cooperative doxorubicin epha2 ers flt1 fuorouracil gdnf inpp5d mcf7 microarrays noncanonical notch1 nutlin responsiveness searches silenced sox9 tlr5 transcriptome vegfr	actg2 adenomatous archived b4ganlt2 bank casp3 cdx1 cdx2 classifier cnn1 col1a1 custom ezr fsp1 genomelab hcellmarkerplex house hybridisation incorporates lgr5 ms4a12 muc2 mucin nox1 ntn1 polyp signatures slc9a2 vwf
Tagcloud (Difference) ?		17beta 3a additive canonical chemotherapeutic chosen combinatorial communications cooperation cooperative doxorubicin epha2 ers flt1 fuorouracil gdnf inpp5d mcf7 microarrays noncanonical notch1 nutlin responsiveness searches silenced sox9 tlr5 transcriptome vegfr	actg2 adenomatous archived b4ganlt2 bank casp3 cdx1 cdx2 classifier cnn1 col1a1 custom ezr fsp1 genomelab hcellmarkerplex house hybridisation incorporates lgr5 ms4a12 muc2 mucin nox1 ntn1 polyp signatures slc9a2 vwf
Tagcloud (Intersection) ?