KRT15 and ARC

Number of citations of the paper that reports this interaction (PubMedID 16189514)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		KRT15	ARC
Description		keratin 15	activity regulated cytoskeleton associated protein
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol Cytoskeleton Intermediate Filament Keratin Filament Extracellular Exosome	Acrosomal Vesicle Cytoplasm Endosome Cytosol Cytoskeleton Plasma Membrane Cell Cortex Postsynaptic Density Actin Cytoskeleton Membrane Dendrite Clathrin-coated Vesicle Membrane Cytoplasmic Vesicle Early Endosome Membrane Cell Projection Neuronal Cell Body Dendritic Spine Membrane Raft Synapse Postsynaptic Membrane Neuronal Ribonucleoprotein Granule Glutamatergic Synapse Virus-like Capsid Extracellular Vesicle
	Molecular Function	Structural Molecule Activity Structural Constituent Of Cytoskeleton Protein Binding Structural Constituent Of Skin Epidermis Scaffold Protein Binding	RNA Binding MRNA Binding Structural Molecule Activity Protein Binding
	Biological Process	Morphogenesis Of An Epithelium Epidermis Development Epithelial Cell Differentiation Intermediate Filament Organization	Endocytosis Cytoskeleton Organization Endoderm Development Long-term Memory Anterior/posterior Pattern Specification Cell Migration Regulation Of Cell Morphogenesis Regulation Of Neuronal Synaptic Plasticity Modulation Of Chemical Synaptic Transmission MRNA Transport Protein Homooligomerization Long-term Synaptic Potentiation Dendritic Spine Morphogenesis Regulation Of Dendritic Spine Morphogenesis Regulation Of Postsynaptic Neurotransmitter Receptor Internalization Vesicle-mediated Intercellular Transport Regulation Of Long-term Synaptic Potentiation Regulation Of Long-term Synaptic Depression
Pathways		Keratinization Formation of the cornified envelope Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin	NGF-stimulated transcription NGF-stimulated transcription
Drugs
Diseases
GWAS			Age-related cognitive decline (attention/processing speed) (slope of z-scores) ( 30954325) Automobile speeding propensity ( 30643258)
Interacting Genes		144 interacting genes: ABI2 ABI3 ABLIM1 AMOT AMOTL2 ANKRD36BP1 APC ARC ARFIP2 ATP5PO BEX2 C1orf216 CALCOCO1 CARD9 CATSPERT CCDC120 CCDC185 CCDC187 CCDC87 CCHCR1 CCNB1IP1 CCNC CDK18 CEP57 COX5B CREB5 CYTH4 DEPP1 DES DEUP1 DGCR6L DRC4 DTNB EFHC1 ENKD1 EPC1 EXOC8 FAM107A FAM110A GFAP GLYCTK HAPLN2 HAUS1 HGS HMG20B HOXB6 IKBIP KANSL1 KDM1A KIAA0408 KIAA1217 KIFC3 KLC3 KLC4 KRT1 KRT18 KRT19 KRT20 KRT3 KRT5 KRT6A KRT6B KRT6C KRT71 KRT72 KRT73 KRT74 KRT76 KRT77 KRT78 KRT79 KRT8 KRT80 KRT81 KRT82 KRT83 KRT85 KRT86 LDOC1 LMO2 LMO4 LNX1 MAD2L1BP MBD3 MCM10 MORN3 MOS NEFL NIF3L1 NOC4L NUDT18 NUP54 OIP5 PCM1 PIK3R2 PKN1 PPP1R18 PRPF31 PRPH PSMA1 PSMB1 PSMC5 RAD51D RAMAC RCOR3 RHPN1 RIBC1 RIBC2 RNF6 RPP25 RSPH14 SGF29 SIRPA SMARCB1 SMARCD1 SMARCE1 SNAPIN SPG21 SSX2IP TBC1D21 TCHP TEKT4 TELO2 TIMM8A TLE5 TMSB4X TRIM42 TRIML2 TSG101 TTC23 TUBGCP4 TXLNA TXLNB TXNDC11 USHBP1 USP2 WAC ZC2HC1C ZFYVE26 ZGPAT ZNF417 ZNF576 ZNF638 ZNF688	7 interacting genes: CSRP2 KRT15 S100P SH2D4A SPTBN4 TBX18 UBE3A
Entrez ID		3866	23237
HPRD ID		01009	12469
Ensembl ID		ENSG00000171346	ENSG00000198576
Uniprot IDs		B3KVF5 P19012	Q7LC44
PDB IDs			6TN7 6TNQ 6TQ0 6YTU 7R1Z 7R23 8QF4 8QF5
Enriched GO Terms of Interacting Partners?		Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Structural Constituent Of Skin Epidermis Keratin Filament Intermediate Filament Keratinization Cytoskeleton Organization Supramolecular Fiber Organization Organelle Organization Protein Binding Cytoskeleton Structural Constituent Of Cytoskeleton Microtubule-based Process Intermediate Filament Cytoskeleton Microtubule-based Movement Centrosome Axonemal A Tubule Inner Sheath Flagellated Sperm Motility Sperm Motility Intermediate Filament Polymerization Or Depolymerization Cilium-dependent Cell Motility Cilium Movement Involved In Cell Motility Brahma Complex NpBAF Complex Establishment Of Cell Polarity Involved In Ameboidal Cell Migration RSC-type Complex Regulation Of Sister Chromatid Segregation NBAF Complex Cell Projection Microtubule Cytoskeleton Organization Motile Cilium Nucleosome Disassembly Microtubule Cilium Movement Sperm Mitochondrial Sheath Assembly Protein-DNA Complex Disassembly	Sperm Entry Positive Regulation Of Golgi Lumen Acidification Sinoatrial Node Cell Fate Commitment Phosphatase Binding Muscle Tissue Development Tissue Development Structural Constituent Of Cytoskeleton Positive Regulation Of Protein Localization To Lysosome Positive Regulation Of Cellular PH Reduction Regulation Of Golgi Lumen Acidification Ureter Development RNA Polymerase II Transcription Repressor Complex Sinoatrial Node Cell Development Neural Plate Pattern Specification Sinoatrial Node Development Cardiac Muscle Cell Fate Commitment Regulation Of SA Node Cell Action Potential Neural Plate Anterior/posterior Regionalization Cytoskeletal Protein-membrane Anchor Activity Clustering Of Voltage-gated Sodium Channels Axon Hillock Cell Body Fiber Paranode Region Of Axon Spectrin
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