KRT15 and ZNF417

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		KRT15	ZNF417
Description		keratin 15	zinc finger protein 417
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol Cytoskeleton Intermediate Filament Keratin Filament Extracellular Exosome	Nucleus
	Molecular Function	Structural Molecule Activity Structural Constituent Of Cytoskeleton Protein Binding Structural Constituent Of Skin Epidermis Scaffold Protein Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Morphogenesis Of An Epithelium Epidermis Development Epithelial Cell Differentiation Intermediate Filament Organization	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Negative Regulation Of DNA-templated Transcription
Pathways		Keratinization Formation of the cornified envelope Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin	Generic Transcription Pathway
Drugs
Diseases
GWAS			Depression in smokers ( 30219690)
Interacting Genes		144 interacting genes: ABI2 ABI3 ABLIM1 AMOT AMOTL2 ANKRD36BP1 APC ARC ARFIP2 ATP5PO BEX2 C1orf216 CALCOCO1 CARD9 CATSPERT CCDC120 CCDC185 CCDC187 CCDC87 CCHCR1 CCNB1IP1 CCNC CDK18 CEP57 COX5B CREB5 CYTH4 DEPP1 DES DEUP1 DGCR6L DRC4 DTNB EFHC1 ENKD1 EPC1 EXOC8 FAM107A FAM110A GFAP GLYCTK HAPLN2 HAUS1 HGS HMG20B HOXB6 IKBIP KANSL1 KDM1A KIAA0408 KIAA1217 KIFC3 KLC3 KLC4 KRT1 KRT18 KRT19 KRT20 KRT3 KRT5 KRT6A KRT6B KRT6C KRT71 KRT72 KRT73 KRT74 KRT76 KRT77 KRT78 KRT79 KRT8 KRT80 KRT81 KRT82 KRT83 KRT85 KRT86 LDOC1 LMO2 LMO4 LNX1 MAD2L1BP MBD3 MCM10 MORN3 MOS NEFL NIF3L1 NOC4L NUDT18 NUP54 OIP5 PCM1 PIK3R2 PKN1 PPP1R18 PRPF31 PRPH PSMA1 PSMB1 PSMC5 RAD51D RAMAC RCOR3 RHPN1 RIBC1 RIBC2 RNF6 RPP25 RSPH14 SGF29 SIRPA SMARCB1 SMARCD1 SMARCE1 SNAPIN SPG21 SSX2IP TBC1D21 TCHP TEKT4 TELO2 TIMM8A TLE5 TMSB4X TRIM42 TRIML2 TSG101 TTC23 TUBGCP4 TXLNA TXLNB TXNDC11 USHBP1 USP2 WAC ZC2HC1C ZFYVE26 ZGPAT ZNF417 ZNF576 ZNF638 ZNF688	170 interacting genes: - ADAMTSL4 AXIN2 BEGAIN BEND5 BEX3 BICD2 C4orf17 CARD9 CBY2 CCDC125 CCDC136 CCDC57 CCDC85B CCNDBP1 CDR2 CDR2L CEP44 CEP70 CEP72 CEP85L CHRDL2 COG6 CSRNP1 CYSRT1 DEF8 DVL3 EFS EZHIP FAM221A FHL2 FHL3 FHL5 FRS3 FSD2 FXR1 GOLGA2 GOLGA6L9 GPRASP3 HMBOX1 HOMEZ HOOK2 HOXA1 HSF2BP IGFBP6 IHO1 IKZF1 INKA1 JADE2 JRK KAT5 KATNBL1 KCTD7 KIF9 KIFC3 KLC3 KRT15 KRT31 KRT35 KRT38 KRT39 KRT40 KRTAP1-1 KRTAP1-3 KRTAP10-1 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-3 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP5-9 KXD1 LHX3 LIMS1 LMO1 LURAP1 LZTS1 LZTS2 MAGEA8 MAST2 MCC MCCD1 MDFI MEIS3 MEOX2 MID2 MIIP MRFAP1L1 MTUS2 MYF5 MYLIP NAB2 NBPF19 NDEL1 NDUFB7 NINL NKAPL NKX3-1 NOTCH2NLA OIP5 PHC2 PICK1 PIH1D2 PLSCR1 PNMA2 PRICKLE4 PRPF31 RCN3 REL RHOQ RNF187 RORB RPGRIP1 RUNDC3A SH2B2 SMARCD1 SMYD5 SPRED1 SPRED2 SPRY1 SPRY2 SSX2IP STX11 SUV39H1 TADA2A TCF4 TEKT4 TFIP11 TLE5 TMCC2 TNS2 TRAF1 TRAF2 TRIB3 TRIM23 TRIM27 TRIM36 TRIM37 TRIM41 TRIM54 TSC1 TSGA10 TXNDC11 U2AF1 USHBP1 VPS16 VPS52 VWC2 ZBTB1 ZBTB10 ZBTB43 ZBTB8A ZBTB9 ZNF165 ZNF19 ZNF20 ZNF547 ZNF572 ZNF587 ZNF69 ZNF71 ZNF768 ZNF774 ZNF837 ZNF85 ZRANB1
Entrez ID		3866	147687
HPRD ID		01009	18341
Ensembl ID		ENSG00000171346	ENSG00000173480
Uniprot IDs		B3KVF5 P19012	M0R230 Q8TAU3
PDB IDs
Enriched GO Terms of Interacting Partners?		Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Structural Constituent Of Skin Epidermis Keratin Filament Intermediate Filament Keratinization Cytoskeleton Organization Supramolecular Fiber Organization Organelle Organization Protein Binding Cytoskeleton Structural Constituent Of Cytoskeleton Microtubule-based Process Intermediate Filament Cytoskeleton Microtubule-based Movement Centrosome Axonemal A Tubule Inner Sheath Flagellated Sperm Motility Sperm Motility Intermediate Filament Polymerization Or Depolymerization Cilium-dependent Cell Motility Cilium Movement Involved In Cell Motility Brahma Complex NpBAF Complex Establishment Of Cell Polarity Involved In Ameboidal Cell Migration RSC-type Complex Regulation Of Sister Chromatid Segregation NBAF Complex Cell Projection Microtubule Cytoskeleton Organization Motile Cilium Nucleosome Disassembly Microtubule Cilium Movement Sperm Mitochondrial Sheath Assembly Protein-DNA Complex Disassembly	Keratin Filament Intermediate Filament Protein Binding Identical Protein Binding Zinc Ion Binding Negative Regulation Of Lens Fiber Cell Differentiation Regulation Of Lens Fiber Cell Differentiation Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Structural Constituent Of Skin Epidermis Cytoskeleton Protein Serine/threonine Kinase Inhibitor Activity Regulation Of Transcription By RNA Polymerase II Regulation Of RNA Metabolic Process Microtubule Binding Cytoskeleton Organization Microtubule-based Process Regulation Of Nucleobase-containing Compound Metabolic Process Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Intermediate Filament Organization Microtubule DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Organelle Organization Hair Cycle Establishment Of Mitotic Spindle Orientation Microtubule Cytoskeleton Organization Negative Regulation Of Neurotrophin TRK Receptor Signaling Pathway Stem Cell Factor Receptor Binding
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