KRT15 and EPC1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		KRT15	EPC1
Gene Name		keratin 15, type I	enhancer of polycomb homolog 1 (Drosophila)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Intermediate Filament Extracellular Vesicular Exosome	Nucleus Nucleoplasm Nuclear Membrane Piccolo NuA4 Histone Acetyltransferase Complex NuA4 Histone Acetyltransferase Complex
	Molecular Function	Structural Constituent Of Cytoskeleton Protein Binding Scaffold Protein Binding	Histone Acetyltransferase Activity
	Biological Process	Epidermis Development	Negative Regulation Of Transcription From RNA Polymerase II Promoter Chromatin Organization Transcription, DNA-templated Regulation Of Growth Histone H4 Acetylation Histone H2A Acetylation Negative Regulation Of Gene Expression, Epigenetic Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter
Pathways			Chromatin modifying enzymes Chromatin organization HATs acetylate histones
Drugs
Diseases
GWAS			Sexual dysfunction (female) ( 22509378)
Protein-Protein Interactions		115 interactors: ABI2 ABI3 ABLIM1 AES ALS2CR11 AMOT AMOTL2 ANKRD36BP1 APC ARC ARFIP2 ATP5O BEX2 C10orf10 C1orf216 CALCOCO1 CCDC101 CCDC120 CCDC185 CCDC67 CCDC87 CCHCR1 CCNB1IP1 CCNC CEP57 COX5B CREB5 CYTH4 DGCR6L EPC1 EXOC8 FAM107A FAM110A GFAP GLYCTK HAUS1 HGS HMG20B HOXB6 IKBIP KANSL1 KIAA0408 KIAA1217 KIFC3 KLC3 KLC4 KRT18 KRT19 KRT20 KRT4 KRT5 KRT6A KRT6B KRT6C KRT71 KRT73 KRT77 KRT79 KRT8 KRT80 KRT81 KRT86 LDOC1 LMO2 LMO4 LNX1 MAD2L1BP MBD3 MCM10 MORN3 MOS NEFL NIF3L1 NOC4L NUDT18 NUP54 OIP5 PCM1 PIK3R2 PKN1 PPP1R18 PRPF31 PRPH PSMA1 PSMB1 PSMC5 RAD51D RCOR3 RHPN1 RIBC1 RIBC2 SIRPA SMARCD1 SMARCE1 SPG21 SSX2IP TCHP TEKT4 TIMM8A TMSB4X TRIM42 TSG101 TUBGCP4 TXLNA TXLNB TXNDC11 USHBP1 USP2 WAC ZC2HC1C ZFYVE26 ZGPAT ZNF417 ZNF576 ZNF638	5 interactors: E2F6 HOPX KRT15 RINT1 TRIM27
Entrez ID		3866	80314
HPRD ID		01009	09941
Ensembl ID		ENSG00000171346	ENSG00000120616
Uniprot IDs		A8MT21 B3KVF5 P19012	Q68DJ2 Q9H2F5
PDB IDs
Enriched GO Terms of Interacting Partners?		Organelle Organization Cytoskeleton Organization Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Cell Cycle Cell Cycle Process Intermediate Filament Organization Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Mitotic Cell Cycle Process Cellular Component Assembly Microtubule-based Process Mitotic Cell Cycle Chromosome Organization Microtubule Cytoskeleton Organization Chromatin Organization Chromatin Modification Cellular Process Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process G1 DNA Damage Checkpoint Intraciliary Transport Involved In Cilium Morphogenesis Anatomical Structure Development RNA Biosynthetic Process Negative Regulation Of Canonical Wnt Signaling Pathway Cell Cycle Checkpoint Transcription, DNA-templated Mitotic Cell Cycle Checkpoint Gene Expression Movement Of Cell Or Subcellular Component Chromatin Remodeling Regulation Of Protein Catabolic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Negative Regulation Of Wnt Signaling Pathway RNA Metabolic Process Developmental Process Histone Acetylation Internal Peptidyl-lysine Acetylation Viral Process Peptidyl-lysine Acetylation Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Positive Regulation Of Canonical Wnt Signaling Pathway Internal Protein Amino Acid Acetylation DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Signal Transduction Involved In Mitotic G1 DNA Damage Checkpoint Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition Negative Regulation Of Cell Cycle Nucleobase-containing Compound Metabolic Process	Regulation Of Signal Transduction Involved In Mitotic G2 DNA Damage Checkpoint Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Interleukin-2 Secretion Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Skeletal Muscle Tissue Regeneration Negative Regulation Of Calcium Ion Import Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Interferon-gamma Secretion Regulation Of DNA Damage Checkpoint Negative Regulation Of Viral Release From Host Cell Regulation Of ER To Golgi Vesicle-mediated Transport Regulation Of Transcription From RNA Polymerase II Promoter Interferon-gamma Production Negative Regulation Of Interleukin-2 Production Negative Regulation Of Viral Transcription Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle Regulation Of Viral Release From Host Cell Regulation Of Calcium Ion Import Trophectodermal Cell Differentiation Negative Regulation Of Cellular Metabolic Process
Tagcloud ?		17beta 3a additive canonical chemotherapeutic chosen combinatorial communications cooperation cooperative doxorubicin epha2 ers flt1 fuorouracil gdnf inpp5d mcf7 microarrays noncanonical notch1 nutlin responsiveness searches silenced sox9 tlr5 transcriptome vegfr	aberrantly aforementioned aurkb bcrp bortezomib ccnb1 cd138 cdc2 cenp centrosome downregulate entity evidences g2 immunomodulatory incurable initiating lenalidomide mdr1 myeloma organs polycomb possess proteasome psma5 sp ube3c upregulated works
Tagcloud (Difference) ?		17beta 3a additive canonical chemotherapeutic chosen combinatorial communications cooperation cooperative doxorubicin epha2 ers flt1 fuorouracil gdnf inpp5d mcf7 microarrays noncanonical notch1 nutlin responsiveness searches silenced sox9 tlr5 transcriptome vegfr	aberrantly aforementioned aurkb bcrp bortezomib ccnb1 cd138 cdc2 cenp centrosome downregulate entity evidences g2 immunomodulatory incurable initiating lenalidomide mdr1 myeloma organs polycomb possess proteasome psma5 sp ube3c upregulated works
Tagcloud (Intersection) ?