KRT15 and EXOC8

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		KRT15	EXOC8
Gene Name		keratin 15, type I	exocyst complex component 8
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Intermediate Filament Extracellular Vesicular Exosome	Exocyst Cytoplasm Late Endosome Cytosol Plasma Membrane Membrane Growth Cone
	Molecular Function	Structural Constituent Of Cytoskeleton Protein Binding Scaffold Protein Binding	Protein Binding Ral GTPase Binding
	Biological Process	Epidermis Development	Exocyst Assembly Organelle Organization Endosome Organization Protein Transport Extracellular Matrix Disassembly Cellular Protein Metabolic Process Exocyst Localization Membrane Organization
Pathways			Peptide hormone metabolism Cargo trafficking to the periciliary membrane Organelle biogenesis and maintenance Translocation of GLUT4 to the plasma membrane VxPx cargo-targeting to cilium Assembly of the primary cilium Insulin processing
Drugs
Diseases
GWAS
Protein-Protein Interactions		115 interactors: ABI2 ABI3 ABLIM1 AES ALS2CR11 AMOT AMOTL2 ANKRD36BP1 APC ARC ARFIP2 ATP5O BEX2 C10orf10 C1orf216 CALCOCO1 CCDC101 CCDC120 CCDC185 CCDC67 CCDC87 CCHCR1 CCNB1IP1 CCNC CEP57 COX5B CREB5 CYTH4 DGCR6L EPC1 EXOC8 FAM107A FAM110A GFAP GLYCTK HAUS1 HGS HMG20B HOXB6 IKBIP KANSL1 KIAA0408 KIAA1217 KIFC3 KLC3 KLC4 KRT18 KRT19 KRT20 KRT4 KRT5 KRT6A KRT6B KRT6C KRT71 KRT73 KRT77 KRT79 KRT8 KRT80 KRT81 KRT86 LDOC1 LMO2 LMO4 LNX1 MAD2L1BP MBD3 MCM10 MORN3 MOS NEFL NIF3L1 NOC4L NUDT18 NUP54 OIP5 PCM1 PIK3R2 PKN1 PPP1R18 PRPF31 PRPH PSMA1 PSMB1 PSMC5 RAD51D RCOR3 RHPN1 RIBC1 RIBC2 SIRPA SMARCD1 SMARCE1 SPG21 SSX2IP TCHP TEKT4 TIMM8A TMSB4X TRIM42 TSG101 TUBGCP4 TXLNA TXLNB TXNDC11 USHBP1 USP2 WAC ZC2HC1C ZFYVE26 ZGPAT ZNF417 ZNF576 ZNF638	20 interactors: BLOC1S6 CCDC85B CEP57L1 EFHC2 EXOC2 HGS IKZF3 KRT15 KRT18 KRT19 KRT20 KRT31 LNX1 MBIP PCM1 RAB3IL1 RALA TADA2A ULK1 USHBP1
Entrez ID		3866	149371
HPRD ID		01009	09943
Ensembl ID		ENSG00000171346	ENSG00000116903
Uniprot IDs		A8MT21 B3KVF5 P19012	Q8IYI6
PDB IDs
Enriched GO Terms of Interacting Partners?		Organelle Organization Cytoskeleton Organization Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Cell Cycle Cell Cycle Process Intermediate Filament Organization Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Mitotic Cell Cycle Process Cellular Component Assembly Microtubule-based Process Mitotic Cell Cycle Chromosome Organization Microtubule Cytoskeleton Organization Chromatin Organization Chromatin Modification Cellular Process Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process G1 DNA Damage Checkpoint Intraciliary Transport Involved In Cilium Morphogenesis Anatomical Structure Development RNA Biosynthetic Process Negative Regulation Of Canonical Wnt Signaling Pathway Cell Cycle Checkpoint Transcription, DNA-templated Mitotic Cell Cycle Checkpoint Gene Expression Movement Of Cell Or Subcellular Component Chromatin Remodeling Regulation Of Protein Catabolic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Negative Regulation Of Wnt Signaling Pathway RNA Metabolic Process Developmental Process Histone Acetylation Internal Peptidyl-lysine Acetylation Viral Process Peptidyl-lysine Acetylation Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Positive Regulation Of Canonical Wnt Signaling Pathway Internal Protein Amino Acid Acetylation DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Signal Transduction Involved In Mitotic G1 DNA Damage Checkpoint Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition Negative Regulation Of Cell Cycle Nucleobase-containing Compound Metabolic Process	Organelle Organization Protein Localization Post-Golgi Vesicle-mediated Transport Cytoskeleton Organization Golgi To Plasma Membrane Transport Membrane Organization Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Microtubule Anchoring Histone H3 Acetylation Inactivation Of MAPK Activity Involved In Osmosensory Signaling Pathway Golgi To Plasma Membrane CFTR Protein Transport Golgi Vesicle Transport Cellular Localization Cytoplasmic Transport Radial Glia Guided Migration Of Cerebellar Granule Cell Exocytosis Establishment Of Localization In Cell Membrane Raft Localization Protein Transport Histone Acetylation Vesicle-mediated Transport Establishment Of Protein Localization Internal Peptidyl-lysine Acetylation Regulation Of Tubulin Deacetylation Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation Intracellular Transport Maintenance Of Protein Location In Cell Intraciliary Transport Involved In Cilium Morphogenesis Secretion Of Lysosomal Enzymes Microtubule-based Transport Protein Acetylation Maintenance Of Protein Location Regulation Of Cell Differentiation Cytoskeleton-dependent Intracellular Transport Maintenance Of Location In Cell Organelle Assembly Negative Regulation Of Collateral Sprouting
Tagcloud ?		17beta 3a additive canonical chemotherapeutic chosen combinatorial communications cooperation cooperative doxorubicin epha2 ers flt1 fuorouracil gdnf inpp5d mcf7 microarrays noncanonical notch1 nutlin responsiveness searches silenced sox9 tlr5 transcriptome vegfr
Tagcloud (Difference) ?		17beta 3a additive canonical chemotherapeutic chosen combinatorial communications cooperation cooperative doxorubicin epha2 ers flt1 fuorouracil gdnf inpp5d mcf7 microarrays noncanonical notch1 nutlin responsiveness searches silenced sox9 tlr5 transcriptome vegfr
Tagcloud (Intersection) ?