BET1L and HNRNPD

Number of citations of the paper that reports this interaction (PubMedID 15231747)
47

Data Source:
BioGRID (two hybrid)

		BET1L	HNRNPD
Description		Bet1 golgi vesicular membrane trafficking protein like	heterogeneous nuclear ribonucleoprotein D
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endosome Golgi Apparatus Golgi Stack Cytosol Membrane SNARE Complex	Chromatin Nucleus Nucleoplasm Cytoplasm Cytosol Postsynaptic Density Synapse Glutamatergic Synapse MCRD-mediated MRNA Stability Complex Ribonucleoprotein Complex
	Molecular Function	SNAP Receptor Activity Protein Binding	Nucleic Acid Binding DNA Binding Minor Groove Of Adenine-thymine-rich DNA Binding Chromatin Binding RNA Binding MRNA Binding Protein Binding MRNA 3'-UTR AU-rich Region Binding Telomeric DNA Binding Histone Deacetylase Binding
	Biological Process	Protein Transport Retrograde Transport, Endosome To Golgi Membrane Fusion Regulation Of Retrograde Vesicle-mediated Transport, Golgi To ER	Liver Development Regulation Of DNA-templated Transcription RNA Processing RNA Catabolic Process Regulation Of Gene Expression Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Cerebellum Development Positive Regulation Of Telomere Maintenance Via Telomerase Response To Estradiol Regulation Of Circadian Rhythm Regulation Of MRNA Stability Positive Regulation Of Translation Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II Rhythmic Process Response To Calcium Ion Response To Electrical Stimulus 3'-UTR-mediated MRNA Destabilization CRD-mediated MRNA Stabilization Cellular Response To Amino Acid Stimulus Cellular Response To Estradiol Stimulus Cellular Response To Nitric Oxide Circadian Regulation Of Translation Negative Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Response To Rapamycin Positive Regulation Of Telomere Capping Response To Sodium Phosphate Cellular Response To Putrescine Hepatocyte Dedifferentiation Positive Regulation Of Cytoplasmic Translation
Pathways		COPI-mediated anterograde transport Intra-Golgi traffic	mRNA Splicing - Major Pathway Processing of Capped Intron-Containing Pre-mRNA
Drugs			Artenimol
Diseases
GWAS		Cataracts ( 34127677) Coronary artery disease ( 33020668) Glycated hemoglobin levels ( 28898252) Gynecologic disease ( 31488892) Gynecologic disease (multivariate analysis) ( 31488892) Intracranial aneurysm ( 22286173) Lumbar spine bone mineral density ( 22504420) Mean corpuscular hemoglobin concentration ( 29403010) Mean corpuscular volume ( 29403010) Mean platelet volume ( 19820697 32888494) Platelet count ( 24026423) Platelet distribution width ( 32888494) Plateletcrit ( 27863252 32888494) Red blood cell count ( 29403010) Red cell distribution width ( 27863252 32888494) Uterine fibroids ( 31249589 31649266 31488892 30194396 21460842) Uterine fibroids (MTAG) ( 31488892)	Chronotype ( 30696823) Coronary artery disease ( 32469254 33020668) Liver enzyme levels (alkaline phosphatase) ( 33972514) Morning person ( 30696823) Refractive error ( 32231278)
Interacting Genes		5 interacting genes: APP GORAB HNRNPD USO1 YKT6	98 interacting genes: ABCC10 ACTB ADGRE5 ARF4 B3GAT3 BET1L BRCA1 C1QBP CAPN1 CD81 CEBPA CINP COG7 COL18A1 CSDE1 CTSB CUTA DGCR2 DHX30 DMAC1 EEF2 ERG ESR1 EXOSC4 FBXL15 FILNC1 FLNA FNDC3B FOS FOXP1 GSK3B GTF3C3 GTSE1 GUK1 HBZ HDAC1 HIRA HMGA1 HNRNPH3 HSPA4 HSPB1 HSPB2 IGF2BP2 IL6 IL7R IMMP2L IMMT ING4 LDHA LINC01232 LSM5 MAP2K1 MAPK6 MEOX2 MPP1 MTA2 MYC NEDD4L NTMT1 OGT P4HB PABPC1 PCBP1 PCBP2 PCSK7 PDLIM7 PEX10 PPOX PRDX3 PRKACA PTBP2 PYCR1 RALY RPSA SAFB SDF2 SEPTIN9 SF3B4 SFN SHISA5 SLC27A5 SLC3A2 SNAPC4 SREK1 SUMO4 SYNCRIP TNF TNPO1 TOP2A TRN-GTT2-7 TSEN34 UBE2I UCP3 UQCRC1 VEGFA VHL YBX1 ZMYM4
Entrez ID		51272	3184
HPRD ID		16547	03206
Ensembl ID		ENSG00000177951	ENSG00000138668
Uniprot IDs		A0A0C4DH16 Q9NYM9	Q14103
PDB IDs			1HD0 1HD1 1IQT 1WTB 1X0F 2Z5N 5IM0
Enriched GO Terms of Interacting Partners?		Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Golgi Apparatus Hepatocyte Dedifferentiation Cellular Response To Putrescine Golgi Vesicle Docking Vesicle Docking Membrane Docking Organelle Localization By Membrane Tethering Transport Vesicle Acetylcholine Receptor Activator Activity PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Circadian Regulation Of Translation Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Membrane Fusion Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Cellular Response To Norepinephrine Stimulus Growth Factor Receptor Binding Main Axon Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Positive Regulation Of Telomere Capping MCRD-mediated MRNA Stability Complex Basal Dendrite Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Response To Rapamycin Cell Dedifferentiation Axon Choice Point Recognition Vesicle Fusion With Golgi Apparatus Heparan Sulfate Binding	RNA Binding CRD-mediated MRNA Stabilization Macromolecule Metabolic Process Positive Regulation Of Translation Ribonucleoprotein Complex Positive Regulation Of Cytoplasmic Translation Negative Regulation Of RNA Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Gene Expression MRNA Metabolic Process Negative Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Regulation Of Programmed Cell Death RNA Metabolic Process Nucleic Acid Binding Regulation Of Apoptotic Process Regulation Of RNA Metabolic Process Response To Stress Negative Regulation Of Apoptotic Process Cellular Response To Stress Regulation Of Cytoplasmic Translation MCRD-mediated MRNA Stability Complex Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Programmed Cell Death Negative Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II CRD-mediated MRNA Stability Complex Positive Regulation Of Gene Expression Transcription Coregulator Binding Regulation Of Gene Expression Regulation Of Translation Nucleic Acid Metabolic Process Regulation Of MiRNA Transcription Focal Adhesion Negative Regulation Of Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II RNA Splicing Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay MRNA Processing Regulation Of Macromolecule Biosynthetic Process Spliceosomal Complex Nucleoplasm Negative Regulation Of Catabolic Process Regulation Of DNA-templated Transcription Regulation Of MiRNA Metabolic Process
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