BET1L and YKT6

Number of citations of the paper that reports this interaction (PubMedID 12388752)
54

Data Source:
HPRD (in vivo)

		BET1L	YKT6
Description		Bet1 golgi vesicular membrane trafficking protein like	YKT6 vesicular SNARE protein
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endosome Golgi Apparatus Golgi Stack Cytosol Membrane SNARE Complex	Golgi Membrane Cytoplasm Mitochondrion Endosome Endoplasmic Reticulum Golgi Apparatus Cytosol Plasma Membrane Membrane Transport Vesicle Cytoplasmic Vesicle Membrane SNARE Complex Cytoplasmic Vesicle Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Neuronal Cell Body Apical Dendrite Basal Dendrite
	Molecular Function	SNAP Receptor Activity Protein Binding	SNAP Receptor Activity Protein Binding Transferase Activity Protein-cysteine S-palmitoyltransferase Activity Cadherin Binding
	Biological Process	Protein Transport Retrograde Transport, Endosome To Golgi Membrane Fusion Regulation Of Retrograde Vesicle-mediated Transport, Golgi To ER	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Vesicle Targeting Vesicle Docking Involved In Exocytosis Protein Transport Vesicle-mediated Transport Retrograde Transport, Endosome To Golgi Membrane Fusion
Pathways		COPI-mediated anterograde transport Intra-Golgi traffic	COPII-mediated vesicle transport COPI-mediated anterograde transport Intra-Golgi traffic RHOA GTPase cycle CDC42 GTPase cycle RAC1 GTPase cycle RHOG GTPase cycle RAC3 GTPase cycle
Drugs
Diseases
GWAS		Cataracts ( 34127677) Coronary artery disease ( 33020668) Glycated hemoglobin levels ( 28898252) Gynecologic disease ( 31488892) Gynecologic disease (multivariate analysis) ( 31488892) Intracranial aneurysm ( 22286173) Lumbar spine bone mineral density ( 22504420) Mean corpuscular hemoglobin concentration ( 29403010) Mean corpuscular volume ( 29403010) Mean platelet volume ( 19820697 32888494) Platelet count ( 24026423) Platelet distribution width ( 32888494) Plateletcrit ( 27863252 32888494) Red blood cell count ( 29403010) Red cell distribution width ( 27863252 32888494) Uterine fibroids ( 31249589 31649266 31488892 30194396 21460842) Uterine fibroids (MTAG) ( 31488892)	Birth weight ( 27680694 31043758) Blood sugar levels ( 29403010) Fasting plasma glucose ( 28270201) Hemoglobin A1c levels ( 29403010) HOMA-B (corrected for HOMA-IR) ( 30369944) Liver enzyme levels (alkaline phosphatase) ( 33972514) Offspring birth weight ( 31043758) Pulse pressure ( 27841878) Serum metabolite levels ( 31636271) Serum metabolite levels (CMS) ( 31636271) Type 2 diabetes ( 30054458)
Interacting Genes		5 interacting genes: APP GORAB HNRNPD USO1 YKT6	3 interacting genes: BET1L HSPA9 USO1
Entrez ID		51272	10652
HPRD ID		16547	16205
Ensembl ID		ENSG00000177951	ENSG00000106636
Uniprot IDs		A0A0C4DH16 Q9NYM9	A0A7I2V4L6 A4D2J0 O15498
PDB IDs			6J74 6J7F 6J7X
Enriched GO Terms of Interacting Partners?		Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Golgi Apparatus Hepatocyte Dedifferentiation Cellular Response To Putrescine Golgi Vesicle Docking Vesicle Docking Membrane Docking Organelle Localization By Membrane Tethering Transport Vesicle Acetylcholine Receptor Activator Activity PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Circadian Regulation Of Translation Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Membrane Fusion Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Cellular Response To Norepinephrine Stimulus Growth Factor Receptor Binding Main Axon Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Positive Regulation Of Telomere Capping MCRD-mediated MRNA Stability Complex Basal Dendrite Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Response To Rapamycin Cell Dedifferentiation Axon Choice Point Recognition Vesicle Fusion With Golgi Apparatus Heparan Sulfate Binding	Golgi Stack Membrane Organization Golgi Vesicle Docking Membrane Fusion Regulation Of Retrograde Vesicle-mediated Transport, Golgi To ER Protein Transport Negative Regulation Of Hematopoietic Stem Cell Differentiation Cellular Localization Establishment Of Protein Localization MIB Complex Negative Regulation Of Erythrocyte Differentiation SAM Complex Calcium Import Into The Mitochondrion Establishment Of Localization In Cell Intracellular Transport HMG Box Domain Binding Response To Gonadotropin-releasing Hormone CAMP Response Element Binding Vesicle Fusion With Golgi Apparatus Negative Regulation Of Hematopoietic Progenitor Cell Differentiation TIM23 Mitochondrial Import Inner Membrane Translocase Complex Regulation Of Hematopoietic Stem Cell Differentiation Intracellular Protein Localization Mitochondrial Calcium Ion Transmembrane Transport Transcytosis Secretory Granule Localization Iron-sulfur Cluster Assembly Intracellular Protein Transport Negative Regulation Of Stem Cell Differentiation Protein Refolding BHLH Transcription Factor Binding Protein Export From Nucleus Golgi Membrane ATP-dependent Protein Folding Chaperone Inner Mitochondrial Membrane Organization SNAP Receptor Activity
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