MRPL37 and HOOK1

		MRPL37	HOOK1
Description		mitochondrial ribosomal protein L37	hook microtubule tethering protein 1
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Ribosome Mitochondrial Large Ribosomal Subunit Ribosome Ribonucleoprotein Complex	Cytoplasm Centrosome Cytoskeleton Microtubule Microtubule Cytoskeleton HOPS Complex FHF Complex
	Molecular Function	RNA Binding Structural Constituent Of Ribosome	Actin Binding Protein Binding Microtubule Binding Identical Protein Binding Protein Homodimerization Activity Dynein Light Intermediate Chain Binding
	Biological Process	Translation Mitochondrial Translation	Golgi Organization Endosome Organization Lysosome Organization Spermatogenesis Spermatid Development Endosome To Lysosome Transport Protein Transport Cell Differentiation Cytoskeleton-dependent Intracellular Transport Cytoplasmic Microtubule Organization Early Endosome To Late Endosome Transport Manchette Assembly Protein Localization To Perinuclear Region Of Cytoplasm
Pathways		Mitochondrial translation initiation Mitochondrial translation elongation Mitochondrial translation elongation Mitochondrial translation termination Mitochondrial ribosome-associated quality control
Drugs
Diseases
GWAS		Carotid plaque burden ( 28282560) Gut microbiota relative abundance (unclassified genus belonging to the order Clostridiales) ( 33208821) Mitochondrial DNA levels ( 25240745)	Alcoholic chronic pancreatitis ( 28754779) Metabolite levels ( 23823483) Night sleep phenotypes ( 27126917)
Interacting Genes		4 interacting genes: SMN1 SREK1 TK1 UBC	46 interacting genes: AKTIP ANK3 ANKRD23 AP1M1 AP4M1 CCDC9 CDC5L CDK4 CUL1 CWF19L2 DENND1B ESS2 EXOSC7 FAM161A FHIP1B HNRNPLL HOOK2 HOOK3 KAT5 LENG1 LMO2 MEOX2 PIAS2 PRPF6 RBM22 RNF10 RPS7 SNW1 TBC1D7 TFIP11 UNKL USP2 UTP14A UTP14C VPS16 VPS18 VPS39 VPS41 ZBTB47 ZNF250 ZNF35 ZNF572 ZNF655 ZNF764 ZNF785 ZNF80
Entrez ID		51253	51361
HPRD ID		14757	07428
Ensembl ID		ENSG00000116221	ENSG00000134709
Uniprot IDs		Q9BZE1 S4R369	Q9UJC3
PDB IDs		3J7Y 3J9M 5OOL 5OOM 6I9R 6NU2 6NU3 6VLZ 6VMI 6ZM5 6ZM6 6ZS9 6ZSA 6ZSB 6ZSC 6ZSD 6ZSE 6ZSG 7A5F 7A5G 7A5H 7A5I 7A5J 7A5K 7L08 7L20 7O9K 7O9M 7ODR 7ODS 7ODT 7OF0 7OF2 7OF3 7OF4 7OF5 7OF6 7OF7 7OG4 7OI6 7OI7 7OI8 7OI9 7OIA 7OIB 7OIC 7OID 7OIE 7PD3 7PO4 7QH6 7QH7 7QI4 7QI5 7QI6 8ANY 8K2A 8K2B 8OIR 8OIT 8PK0 8QSJ 8QU1 8QU5 8RRI 8XT0 8XT1 8XT2 8XT3
Enriched GO Terms of Interacting Partners?		DNA Synthesis Involved In Mitotic DNA Replication Thymidine Metabolic Process Thymidine Biosynthetic Process Thymidine Kinase Activity Manchette Assembly FHF Complex Protein Localization To Perinuclear Region Of Cytoplasm Deoxyribonucleoside Monophosphate Biosynthetic Process SMN Complex Gemini Of Cajal Bodies RNA Splicing Pyrimidine Nucleoside Metabolic Process Protein Tag Activity HOPS Complex SMN-Sm Protein Complex MRNA Processing RNA Binding DNA-templated Transcription Termination Early Endosome To Late Endosome Transport Dynein Light Intermediate Chain Binding	HOPS Complex Endosome To Lysosome Transport Vacuolar Transport Lysosomal Transport FHF Complex Protein Localization To Perinuclear Region Of Cytoplasm Lysosome Organization Vacuole Organization Regulation Of SNARE Complex Assembly Endosomal Vesicle Fusion Catalytic Step 2 Spliceosome Vesicle Organization Early Endosome To Late Endosome Transport MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Clathrin-coated Vesicle AP-3 Adaptor Complex Endosome Organization RNA Processing Regulation Of Transcription By RNA Polymerase II Lysosomal HOPS Complex Protein Transport Endosomal Transport Spliceosomal Complex MRNA Processing Establishment Of Protein Localization MRNA Metabolic Process Zinc Ion Binding RNA Splicing U2-type Catalytic Step 2 Spliceosome Vesicle-mediated Transport Nucleus Intracellular Transport Regulation Of Macromolecule Metabolic Process RNA Metabolic Process CORVET Complex Regulation Of Gene Expression Vesicle Fusion Regulation Of Metabolic Process Nuclear Speck Organelle Membrane Fusion Regulation Of DNA-templated Transcription Positive Regulation Of RNA Splicing Regulation Of Macromolecule Biosynthetic Process Regulation Of RNA Biosynthetic Process Cellular Localization Regulation Of Primary Metabolic Process Nucleic Acid Metabolic Process Protein Targeting To Vacuole Clathrin Adaptor Complex
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