ABI3 and BLOC1S5

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ABI3	BLOC1S5
Description		ABI family member 3	biogenesis of lysosomal organelles complex 1 subunit 5
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Postsynaptic Density Membrane Lamellipodium SCAR Complex Dendritic Spine Dendritic Shaft Postsynapse Actin-based Cell Projection Glutamatergic Synapse	Transport Vesicle BLOC-1 Complex Axon Cytoplasm Microvesicle
	Molecular Function	Protein Binding Signaling Adaptor Activity Identical Protein Binding Actin Filament Binding	Protein Binding
	Biological Process	Neuron Migration Defense Response To Tumor Cell Negative Regulation Of Lamellipodium Assembly Peptidyl-tyrosine Phosphorylation Actin Cytoskeleton Organization Regulation Of Cell Migration Cell Projection Morphogenesis Regulation Of Dendritic Spine Morphogenesis Modification Of Postsynaptic Actin Cytoskeleton Regulation Of Postsynaptic Density Assembly Negative Regulation Of Ruffle Assembly Negative Regulation Of Protein Localization To Plasma Membrane Positive Regulation Of Cellular Senescence	Anterograde Axonal Transport Vesicle-mediated Transport Neuron Projection Development Melanosome Transport Melanosome Organization Otolith Morphogenesis Endosome To Melanosome Transport Developmental Pigmentation Anterograde Synaptic Vesicle Transport Positive Regulation Of Pigment Cell Differentiation
Pathways
Drugs
Diseases
GWAS		Alzheimer's disease (late onset) ( 28714976) Alzheimer's disease or family history of Alzheimer's disease ( 30617256) Asthma ( 31619474) Family history of Alzheimer's disease ( 30617256) Prostate cancer ( 23535732) Refractive error ( 32231278)	Response to (pegylated) interferon in HBeAg-negative hepatitis B ( 30715261)
Interacting Genes		77 interacting genes: ABI2 ABI3BP ACTN3 AGTR1 ARHGAP9 ARMC7 BAIAP2L2 BFSP2 BLOC1S5 CENPQ CEP170P1 CEP44 CYFIP2 DESI1 DTNB DTNBP1 EIF3H EIF3M EMILIN1 ENAH EVL FAM124B FARSA FBF1 GNG13 GOLM1 GRB2 HOMER1 HOMER2 HOMER3 IFT20 IHO1 KANK2 KIAA0408 KIFC3 KLC3 KLC4 KRT13 KRT14 KRT15 KRT24 KRT28 KRT31 KRT35 KRT36 KRT38 MAGEA12 MED29 MIS18A MRFAP1 MRFAP1L1 NCK2 NDEL1 NHSL2 NUP58 OIP5 PAK1 PAK2 PSMA1 RUFY3 RUNX1T1 SH3BP1 SMARCD1 SNAP23 SOS1 STX1A STX2 SUFU TMEM147 TRAF4 TXN2 VARS2 VASP WAS WASF1 WASF2 WASHC1	15 interacting genes: ABI2 ABI3 APP BLOC1S1 BLOC1S2 BLOC1S4 DTNBP1 HSBP1 LRRK1 OIP5 PBX2 PKNOX1 SMARCD1 SNAPIN TSNAX
Entrez ID		51225	63915
HPRD ID		05900	06289
Ensembl ID		ENSG00000108798	ENSG00000188428
Uniprot IDs		Q9P2A4	A0A0A0MTN6 Q8TDH9
PDB IDs
Enriched GO Terms of Interacting Partners?		Supramolecular Fiber Organization Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Regulation Of Actin Filament Organization Intermediate Filament Organization Structural Constituent Of Skin Epidermis Keratin Filament Regulation Of Actin Cytoskeleton Organization Cytoskeleton Regulation Of Actin Filament-based Process Regulation Of Supramolecular Fiber Organization Structural Molecule Activity SH3 Domain Binding Anatomical Structure Morphogenesis Morphogenesis Of An Epithelium Intermediate Filament Cytoskeleton Organization Regulation Of Cytoskeleton Organization Lamellipodium Regulation Of Actin Polymerization Or Depolymerization Regulation Of Actin Filament Length Actin Filament Organization Tissue Morphogenesis Positive Regulation Of Supramolecular Fiber Organization G Protein-coupled Glutamate Receptor Binding SCAR Complex Positive Regulation Of Cytoskeleton Organization Organelle Organization Actin Polymerization Or Depolymerization Cytosol Regulation Of Actin Filament Polymerization Epithelial Cell Differentiation Anchoring Junction Regulation Of Cellular Component Size Protein Binding Positive Regulation Of Protein Polymerization Positive Regulation Of Actin Filament Polymerization Cellular Component Assembly Positive Regulation Of Cellular Component Biogenesis Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation Regulation Of Arp2/3 Complex-mediated Actin Nucleation Profilin Binding Developmental Process Regulation Of Organelle Organization Regulation Of Actin Nucleation Postsynaptic Density Vesicle Membrane Cell Projection Organization Positive Regulation Of Actin Nucleation Regulation Of Store-operated Calcium Entry	Axo-dendritic Transport Anterograde Synaptic Vesicle Transport BLOC-1 Complex Axon Cytoplasm Axonal Transport Transport Along Microtubule Organelle Transport Along Microtubule Synaptic Vesicle Transport Melanosome Organization Pigment Granule Organization Cytoskeleton-dependent Intracellular Transport Microtubule-based Transport Vesicle Transport Along Microtubule Anterograde Axonal Transport Vesicle Cytoskeletal Trafficking Microtubule-based Movement Establishment Of Vesicle Localization Regulation Of Lysosome Size BORC Complex Vesicle Localization Establishment Of Organelle Localization Regulation Of Endosome Size Cytoplasmic Side Of Lysosomal Membrane Regulation Of Vesicle Size Cell Projection Organization Platelet Dense Granule Organization Organelle Localization Neuron Projection Development Microtubule-based Process Vesicle Organization Regulation Of Postsynapse Organization Regulation Of Dendritic Spine Morphogenesis Dendritic Spine Lysosome Localization Actin-based Cell Projection Secretory Granule Organization Intracellular Transport SCAR Complex Plasma Membrane Bounded Cell Projection Organization Cell Projection Morphogenesis Regulation Of Synapse Organization Cellular Localization Establishment Of Localization In Cell Regulation Of Plasma Membrane Bounded Cell Projection Organization Regulation Of Cell Projection Organization Positive Regulation Of Receptor Internalization Regulation Of Neuron Projection Development Hemopoiesis Negative Regulation Of Cell Projection Organization Regulation Of Lamellipodium Assembly
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?