BLOC1S5 and BLOC1S2

Number of citations of the paper that reports this interaction (PubMedID 15102850)
0

Data Source:
HPRD (in vivo)

		BLOC1S5	BLOC1S2
Description		biogenesis of lysosomal organelles complex 1 subunit 5	biogenesis of lysosomal organelles complex 1 subunit 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Transport Vesicle BLOC-1 Complex Axon Cytoplasm Microvesicle	Gamma-tubulin Complex Nucleus Cytoplasm Mitochondrion Lysosome Lysosomal Membrane Centrosome Cytosol Cytoskeleton Membrane BLOC-1 Complex Cytoplasmic Side Of Lysosomal Membrane BORC Complex Axon Cytoplasm
	Molecular Function	Protein Binding	Protein Binding Gamma-tubulin Binding
	Biological Process	Anterograde Axonal Transport Vesicle-mediated Transport Neuron Projection Development Melanosome Transport Melanosome Organization Otolith Morphogenesis Endosome To Melanosome Transport Developmental Pigmentation Anterograde Synaptic Vesicle Transport Positive Regulation Of Pigment Cell Differentiation	Microtubule Nucleation Anterograde Axonal Transport Positive Regulation Of Cell Population Proliferation Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Endosomal Transport Neuron Projection Development Lysosome Localization Melanosome Organization Positive Regulation Of DNA-templated Transcription Anterograde Synaptic Vesicle Transport Regulation Of Endosome Size Platelet Dense Granule Organization Regulation Of Lysosome Size Organelle Transport Along Microtubule Mitochondrial Outer Membrane Permeabilization
Pathways
Drugs
Diseases
GWAS		Response to (pegylated) interferon in HBeAg-negative hepatitis B ( 30715261)	Refractive error ( 32231278)
Interacting Genes		15 interacting genes: ABI2 ABI3 APP BLOC1S1 BLOC1S2 BLOC1S4 DTNBP1 HSBP1 LRRK1 OIP5 PBX2 PKNOX1 SMARCD1 SNAPIN TSNAX	36 interacting genes: APP ARFIP2 BFSP2 BLOC1S1 BLOC1S3 BLOC1S4 BLOC1S5 BLOC1S6 C8orf33 CCDC146 CCHCR1 CCNC CTNNA3 DCTN2 ERP27 EXOC8 FAM161B FAM9B GADD45G GEM HMOX2 KRT26 MEST P4HA3 PAM16 PICK1 RDH11 SH2D4A SNAPIN SSC5D STX2 TNNT1 TRIML2 TTC3 WASHC1 WASHC3
Entrez ID		63915	282991
HPRD ID		06289	12526
Ensembl ID		ENSG00000188428	ENSG00000196072
Uniprot IDs		A0A0A0MTN6 Q8TDH9	A0A087X1N6 F1T0F0 Q6QNY1
PDB IDs
Enriched GO Terms of Interacting Partners?		Axo-dendritic Transport Anterograde Synaptic Vesicle Transport BLOC-1 Complex Axon Cytoplasm Axonal Transport Transport Along Microtubule Organelle Transport Along Microtubule Synaptic Vesicle Transport Melanosome Organization Pigment Granule Organization Cytoskeleton-dependent Intracellular Transport Microtubule-based Transport Vesicle Transport Along Microtubule Anterograde Axonal Transport Vesicle Cytoskeletal Trafficking Microtubule-based Movement Establishment Of Vesicle Localization Regulation Of Lysosome Size BORC Complex Vesicle Localization Establishment Of Organelle Localization Regulation Of Endosome Size Cytoplasmic Side Of Lysosomal Membrane Regulation Of Vesicle Size Cell Projection Organization Platelet Dense Granule Organization Organelle Localization Neuron Projection Development Microtubule-based Process Vesicle Organization Regulation Of Postsynapse Organization Regulation Of Dendritic Spine Morphogenesis Dendritic Spine Lysosome Localization Actin-based Cell Projection Secretory Granule Organization Intracellular Transport SCAR Complex Plasma Membrane Bounded Cell Projection Organization Cell Projection Morphogenesis Regulation Of Synapse Organization Cellular Localization Establishment Of Localization In Cell Regulation Of Plasma Membrane Bounded Cell Projection Organization Regulation Of Cell Projection Organization Positive Regulation Of Receptor Internalization Regulation Of Neuron Projection Development Hemopoiesis Negative Regulation Of Cell Projection Organization Regulation Of Lamellipodium Assembly	Anterograde Synaptic Vesicle Transport BLOC-1 Complex Synaptic Vesicle Transport Melanosome Organization Pigment Granule Organization Axo-dendritic Transport Anterograde Axonal Transport Vesicle Transport Along Microtubule Vesicle Cytoskeletal Trafficking Establishment Of Vesicle Localization Axon Cytoplasm Axonal Transport Vesicle Localization Organelle Localization Organelle Transport Along Microtubule Intracellular Transport Transport Along Microtubule Melanosome Transport Cellular Localization Establishment Of Melanosome Localization Pigment Granule Transport Cytoskeleton-dependent Intracellular Transport Establishment Of Localization In Cell Melanosome Localization Pigment Granule Localization Vesicle Organization Regulation Of Arp2/3 Complex-mediated Actin Nucleation Microtubule-based Transport Microvesicle Regulation Of Actin Nucleation Plasma Membrane Bounded Cell Projection Organization Endosome To Melanosome Transport Microtubule-based Movement Establishment Of Organelle Localization Protein Transport Cell Projection Organization Secretion By Cell Organelle Organization Membrane Curvature Sensor Activity Microtubule-based Process Establishment Of Protein Localization Secretion Of Lysosomal Enzymes Neuron Projection Development Exocytosis Positive Regulation Of Pigment Cell Differentiation Secretion Regulation Of Lysosome Size BORC Complex Positive Regulation Of Developmental Pigmentation Pigmentation
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