BLOC1S5 and OIP5

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		BLOC1S5	OIP5
Description		biogenesis of lysosomal organelles complex 1 subunit 5	Opa interacting protein 5
Image		No pdb structure
GO Annotations	Cellular Component	Transport Vesicle BLOC-1 Complex Axon Cytoplasm Microvesicle	Chromosome, Centromeric Region Chromatin Nucleus Nucleoplasm Chromosome Chromocenter Cajal Body Nuclear Speck CENP-A Recruiting Complex
	Molecular Function	Protein Binding	Protein Binding Identical Protein Binding Metal Ion Binding
	Biological Process	Anterograde Axonal Transport Vesicle-mediated Transport Neuron Projection Development Melanosome Transport Melanosome Organization Otolith Morphogenesis Endosome To Melanosome Transport Developmental Pigmentation Anterograde Synaptic Vesicle Transport Positive Regulation Of Pigment Cell Differentiation	Chromosome Segregation Cell Communication CENP-A Containing Chromatin Assembly Cell Division Pericentric Heterochromatin Organization
Pathways			Deposition of new CENPA-containing nucleosomes at the centromere
Drugs
Diseases
GWAS		Response to (pegylated) interferon in HBeAg-negative hepatitis B ( 30715261)	Allergic disease (asthma, hay fever or eczema) ( 29785011) Ulcerative colitis ( 28067908)
Interacting Genes		15 interacting genes: ABI2 ABI3 APP BLOC1S1 BLOC1S2 BLOC1S4 DTNBP1 HSBP1 LRRK1 OIP5 PBX2 PKNOX1 SMARCD1 SNAPIN TSNAX	142 interacting genes: A1CF ABI2 ABI3 ABL2 AGXT BCAS2 BEX2 BFSP2 BLOC1S5 BRAF C1orf94 C21orf91 C7orf57 CASP10 CBY2 CCDC22 CCDC24 CCHCR1 CDR2L CEP57 CERK CHCHD2 CIMIP1 COX5B CRACR2A CTNNA3 DMRT3 DTNBP1 DTX2 DUSP21 EFHC1 EIF4ENIF1 ESS2 FAM161B FAM222B FOXJ1 FSD2 GADD45GIP1 GCC1 GEM GLIS2 GPANK1 GPS2 HAPLN2 HGS HJURP HOXB5 HOXB9 HOXC8 HSF4 IL16 KANK2 KDM1A KIF9 KLHL38 KLHL42 KNSTRN KRT14 KRT15 KRT27 KRT3 KRT35 KRT37 KRT40 KRT6B KRT75 KRT81 KRT83 KRT86 KRTAP13-2 KRTAP19-5 KRTAP19-6 LENG1 MECOM MED4 MEIS2 MGAT5B MIIP MIS18A MIS18BP1 MISP MORN3 MYEF2 MYRIP NDUFAB1 NECAB2 NUP54 NUP62 P4HA3 PATZ1 PEX19 PHETA1 PITX2 PLAGL2 POLR2J POU6F2 PRR35 PSMB1 RAB26 RABGEF1 RAF1 RARG RIBC1 RUNX1T1 RUSC1 S100Z SAMD7 SAXO1 SAXO4 SHISA6 SKIL SMARCE1 SNRNP25 SNRPB SOHLH1 SORBS3 SPATA24 SPMIP4 SYCE1L TEKT3 TEX12 TFAP2D TFIP11 TIMM8A TLX3 TMPO TPM3 TPRX1 TRIB3 TRIM73 TRIP6 TROAP TSSK3 USHBP1 USP2 USP54 WASHC1 YTHDF1 ZIC1 ZMAT1 ZNF417 ZNF655
Entrez ID		63915	11339
HPRD ID		06289	09352
Ensembl ID		ENSG00000188428	ENSG00000104147
Uniprot IDs		A0A0A0MTN6 Q8TDH9	O43482
PDB IDs			7SFY
Enriched GO Terms of Interacting Partners?		Axo-dendritic Transport Anterograde Synaptic Vesicle Transport BLOC-1 Complex Axon Cytoplasm Axonal Transport Transport Along Microtubule Organelle Transport Along Microtubule Synaptic Vesicle Transport Melanosome Organization Pigment Granule Organization Cytoskeleton-dependent Intracellular Transport Microtubule-based Transport Vesicle Transport Along Microtubule Anterograde Axonal Transport Vesicle Cytoskeletal Trafficking Microtubule-based Movement Establishment Of Vesicle Localization Regulation Of Lysosome Size BORC Complex Vesicle Localization Establishment Of Organelle Localization Regulation Of Endosome Size Cytoplasmic Side Of Lysosomal Membrane Regulation Of Vesicle Size Cell Projection Organization Platelet Dense Granule Organization Organelle Localization Neuron Projection Development Microtubule-based Process Vesicle Organization Regulation Of Postsynapse Organization Regulation Of Dendritic Spine Morphogenesis Dendritic Spine Lysosome Localization Actin-based Cell Projection Secretory Granule Organization Intracellular Transport SCAR Complex Plasma Membrane Bounded Cell Projection Organization Cell Projection Morphogenesis Regulation Of Synapse Organization Cellular Localization Establishment Of Localization In Cell Regulation Of Plasma Membrane Bounded Cell Projection Organization Regulation Of Cell Projection Organization Positive Regulation Of Receptor Internalization Regulation Of Neuron Projection Development Hemopoiesis Negative Regulation Of Cell Projection Organization Regulation Of Lamellipodium Assembly	Structural Constituent Of Skin Epidermis Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Intermediate Filament Organization Intermediate Filament Keratin Filament Protein Binding Supramolecular Fiber Organization Cytoskeleton Axonemal A Tubule Inner Sheath Cytoskeleton Organization Structural Molecule Activity Organelle Organization Sperm Flagellum Keratinization Motile Cilium CENP-A Containing Chromatin Assembly Pericentric Heterochromatin Organization CENP-A Recruiting Complex
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