BLOC1S5 and HSBP1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		BLOC1S5	HSBP1
Description		biogenesis of lysosomal organelles complex 1 subunit 5	heat shock factor binding protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Transport Vesicle BLOC-1 Complex Axon Cytoplasm Microvesicle	Nucleus Nucleoplasm Cytosol Axon Cytoplasm
	Molecular Function	Protein Binding	Transcription Corepressor Activity Protein Binding Identical Protein Binding
	Biological Process	Anterograde Axonal Transport Vesicle-mediated Transport Neuron Projection Development Melanosome Transport Melanosome Organization Otolith Morphogenesis Endosome To Melanosome Transport Developmental Pigmentation Anterograde Synaptic Vesicle Transport Positive Regulation Of Pigment Cell Differentiation	Negative Regulation Of Transcription By RNA Polymerase II Muscle Contraction Axonal Transport Of Mitochondrion Endodermal Cell Differentiation Cellular Heat Acclimation
Pathways			HSF1 activation Attenuation phase HSF1-dependent transactivation
Drugs
Diseases
GWAS		Response to (pegylated) interferon in HBeAg-negative hepatitis B ( 30715261)	Lead levels ( 26025379) Metabolite levels ( 23823483) Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1) ( 26503814) Response to platinum-based neoadjuvant chemotherapy in cervical cancer ( 28120872)
Interacting Genes		15 interacting genes: ABI2 ABI3 APP BLOC1S1 BLOC1S2 BLOC1S4 DTNBP1 HSBP1 LRRK1 OIP5 PBX2 PKNOX1 SMARCD1 SNAPIN TSNAX	20 interacting genes: BLOC1S5 CYSRT1 GORASP2 HSF1 HSPA1A KIAA1217 KIFC3 KRTAP1-1 KRTAP10-3 KRTAP10-7 KRTAP10-9 LNX1 MPP7 NOTCH2NLA SDCBP SDCBP2 UBC WASHC1 WASHC3 ZBTB25
Entrez ID		63915	3281
HPRD ID		06289	05185
Ensembl ID		ENSG00000188428	ENSG00000230989
Uniprot IDs		A0A0A0MTN6 Q8TDH9	O75506
PDB IDs			3CI9
Enriched GO Terms of Interacting Partners?		Axo-dendritic Transport Anterograde Synaptic Vesicle Transport BLOC-1 Complex Axon Cytoplasm Axonal Transport Transport Along Microtubule Organelle Transport Along Microtubule Synaptic Vesicle Transport Melanosome Organization Pigment Granule Organization Cytoskeleton-dependent Intracellular Transport Microtubule-based Transport Vesicle Transport Along Microtubule Anterograde Axonal Transport Vesicle Cytoskeletal Trafficking Microtubule-based Movement Establishment Of Vesicle Localization Regulation Of Lysosome Size BORC Complex Vesicle Localization Establishment Of Organelle Localization Regulation Of Endosome Size Cytoplasmic Side Of Lysosomal Membrane Regulation Of Vesicle Size Cell Projection Organization Platelet Dense Granule Organization Organelle Localization Neuron Projection Development Microtubule-based Process Vesicle Organization Regulation Of Postsynapse Organization Regulation Of Dendritic Spine Morphogenesis Dendritic Spine Lysosome Localization Actin-based Cell Projection Secretory Granule Organization Intracellular Transport SCAR Complex Plasma Membrane Bounded Cell Projection Organization Cell Projection Morphogenesis Regulation Of Synapse Organization Cellular Localization Establishment Of Localization In Cell Regulation Of Plasma Membrane Bounded Cell Projection Organization Regulation Of Cell Projection Organization Positive Regulation Of Receptor Internalization Regulation Of Neuron Projection Development Hemopoiesis Negative Regulation Of Cell Projection Organization Regulation Of Lamellipodium Assembly	Keratin Filament Intermediate Filament Negative Regulation Of Inclusion Body Assembly Response To Unfolded Protein WASH Complex Cellular Response To Unfolded Protein Regulation Of Inclusion Body Assembly
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